Publication

Asymptomatic bacteriuria and urinary tract infections in women: focus on diabetes mellitus and pregnancy

Schneeberger, C., 2014, [S.l.]: [S.n.]. 211 p.

Research output: ThesisThesis fully internal (DIV)Academic

Copy link to clipboard

Documents

  • Title and contents

    Final publisher's version, 307 KB, PDF document

  • Chapter 1

    Final publisher's version, 119 KB, PDF document

  • Chapter 2

    Final publisher's version, 446 KB, PDF document

  • Chapter 3

    Final publisher's version, 278 KB, PDF document

  • Chapter 4

    Final publisher's version, 423 KB, PDF document

  • Chapter 5

    Final publisher's version, 391 KB, PDF document

  • Chapter 6

    Final publisher's version, 1011 KB, PDF document

    Embargo ends: 01/01/9999

  • Chapter 6 Publisher's version

    Final publisher's version, 255 KB, PDF document

  • Chapter 7

    Final publisher's version, 646 KB, PDF document

  • Chapter 8

    Final publisher's version, 566 KB, PDF document

    Embargo ends: 01/01/9999

  • Chapter 8 Publisher's version

    Final publisher's version, 348 KB, PDF document

  • Chapter 9

    Final publisher's version, 968 KB, PDF document

  • Chapter 10

    Final publisher's version, 966 KB, PDF document

  • Chapter 11

    Final publisher's version, 333 KB, PDF document

  • Chapter 12

    Final publisher's version, 628 KB, PDF document

  • Addendum

    Final publisher's version, 826 KB, PDF document

  • Complete dissertation

    Final publisher's version, 1 MB, PDF document

  • Propositions

    Final publisher's version, 225 KB, PDF document

  • Caroline Schneeberger
There is a shortage of evidence for clinical guidelines on diagnosis and management of both asymptomatic bacteriuria (the presence of bacteria in urine without symptoms of an infection) and urinary tract infections in women with diabetes and pregnant women. Asymptomatic bacteriuria and urinary tract infections in these two risk groups may have far-reaching consequences such as pyelonephritis and preterm birth. The results of the studies in this thesis can be used to fill some of the knowledge gaps.

Treatment of urinary tract infections in women with diabetes: Schneeberger found that women with diabetes more often experienced a recurrent urinary tract infection despite the fact that they more often received a longer initial antibiotic treatment than women without diabetes.

Diagnosis of bacteriuria in pregnant women: contamination of urine samples with for example skin flora may distort the diagnosis of bacteriuria. In pregnant women, the contamination rate of midstream samples is comparable with the contamination rates of clean-catch samples, which are more unpractical and time-consuming. Therefore, we recommend a midstream sample to assess bacteriuria in pregnant women.

Recurrent urinary tract infections in pregnant women: a systematic literature review showed that there are no sufficient studies to identify the optimal intervention to prevent recurrent urinary tract infections in pregnant women.

Screening for asymptomatic bacteriuria: A low (<5%) number of pregnant women with and without diabetes with asymptomatic bacteriuria were identified. Neither asymptomatic bacteriuria nor urinary tract infections were associated with preterm birth or low birth weight babies in this population. Our data discourage a routine screen and treat policy for asymptomatic bacteriuria in pregnant women with DM.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
Supervisors/Advisors
  • Stolk, Ronald, Supervisor
  • Erwich, Johannes, Supervisor
  • Geerlings, Suzanne E., Co-supervisor, External person
  • Hoepelman, A. I. M., Assessment committee, External person
  • Scherjon, Sicco, Assessment committee
  • Vandenbroucke-Grauls, C. M. J. E., Assessment committee, External person
Award date3-Dec-2014
Place of Publication[S.l.]
Publisher
Print ISBNs978-90-367-7363-8
Electronic ISBNs978-90-367-7362-1
Publication statusPublished - 2014

    Keywords

  • Vrouwen, Diabetes mellitus, Urinewegen, Bacterie͏̈le $infecties, Zwangerschap Proefschriften (vorm), Zwangerschap

View graph of relations

Download statistics

No data available

ID: 14342642