Publication

Association Between Preoperative Vitamin D Status and Short-Term Physical Performance after Total Hip Arthroplasty: A Prospective Study

Visser, E., de Roos, N. M., Oosting, E., Endenburg, S. C. & Dronkers, J. J., Oct-2018, In : Annals of nutrition and metabolism. 73, 3, p. 252-260 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Visser, E., de Roos, N. M., Oosting, E., Endenburg, S. C., & Dronkers, J. J. (2018). Association Between Preoperative Vitamin D Status and Short-Term Physical Performance after Total Hip Arthroplasty: A Prospective Study. Annals of nutrition and metabolism, 73(3), 252-260. https://doi.org/10.1159/000492938

Author

Visser, Edith ; de Roos, Nicole M. ; Oosting, Ellen ; Endenburg, Silvia C. ; Dronkers, Jaap J. / Association Between Preoperative Vitamin D Status and Short-Term Physical Performance after Total Hip Arthroplasty : A Prospective Study. In: Annals of nutrition and metabolism. 2018 ; Vol. 73, No. 3. pp. 252-260.

Harvard

Visser, E, de Roos, NM, Oosting, E, Endenburg, SC & Dronkers, JJ 2018, 'Association Between Preoperative Vitamin D Status and Short-Term Physical Performance after Total Hip Arthroplasty: A Prospective Study', Annals of nutrition and metabolism, vol. 73, no. 3, pp. 252-260. https://doi.org/10.1159/000492938

Standard

Association Between Preoperative Vitamin D Status and Short-Term Physical Performance after Total Hip Arthroplasty : A Prospective Study. / Visser, Edith; de Roos, Nicole M.; Oosting, Ellen; Endenburg, Silvia C.; Dronkers, Jaap J.

In: Annals of nutrition and metabolism, Vol. 73, No. 3, 10.2018, p. 252-260.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Visser E, de Roos NM, Oosting E, Endenburg SC, Dronkers JJ. Association Between Preoperative Vitamin D Status and Short-Term Physical Performance after Total Hip Arthroplasty: A Prospective Study. Annals of nutrition and metabolism. 2018 Oct;73(3):252-260. https://doi.org/10.1159/000492938


BibTeX

@article{31827b2665cd4459983286aa65096bfd,
title = "Association Between Preoperative Vitamin D Status and Short-Term Physical Performance after Total Hip Arthroplasty: A Prospective Study",
abstract = "BACKGROUND: Insufficient serum vitamin D concentrations (50-75 nmol/L) are prevalent in 40-65{\%} of patients who require total hip arthroplasty (THA). This could impair physical recovery after surgery. This study investigated the association between preoperative vitamin D status and physical performance after THA. Additionally, postoperative changes in vitamin D concentrations were measured.METHODS: We included 87 patients scheduled for elective THA and aged ≥65 years. Three groups were recruited: patients classified as vitamin D deficient (< 50 nmol/L, n = 23), insufficient (50-75 nmol/L, n = 32), or sufficient (> 75 nmol/L, n = 32). Serum 25-hydroxyvitamin D3 (25[OH]D3) concentration and physical performance were measured perioperatively. Linear mixed models were used to examine differences between groups.RESULTS: Change in physical performance over time was not affected by preoperative vitamin D status. In contrast, for physical activity, both vitamin D (p = 0.021) and time (p < 0.001) effect was seen: from 80.2 ± 25.8 to 58.1 ± 17.8 min/day in the deficient group, 143.7 ± 19.8 to 92.9 ± 11.5 min/day in the insufficient group, and 108.1 ± 20.9 to 62.3 ± 12.9 min/day in the sufficient group. The Chair Stand Test, Timed Up and Go test, and 10-Meter Walking Test also improved significantly over time, but independent of vitamin D status. An increase in 25(OH)D3 concentration 6 weeks postoperatively was correlated with improved hip function (Pearson's r = -0.471, p = 0.018). Overall, serum 25(OH)D3 declined with 32{\%} one day after surgery (p < 0.001), to nearly return to baseline values 6 weeks later in all groups.CONCLUSION: Vitamin D status did not appear to affect physical recovery after THA. The drop in vitamin D after surgery deserves further investigation, but could possibly be explained by hemodilution.",
keywords = "MUSCLE STRENGTH, SKELETAL-MUSCLE, OLDER-ADULTS, D DEFICIENCY, OSTEOARTHRITIS, MOBILITY, POWER, KNEE, SUPPLEMENTATION, METAANALYSIS",
author = "Edith Visser and {de Roos}, {Nicole M.} and Ellen Oosting and Endenburg, {Silvia C.} and Dronkers, {Jaap J.}",
note = "{\circledC} 2018 The Author(s) Published by S. Karger AG, Basel.",
year = "2018",
month = "10",
doi = "10.1159/000492938",
language = "English",
volume = "73",
pages = "252--260",
journal = "Annals of nutrition and metabolism",
issn = "0250-6807",
publisher = "KARGER",
number = "3",

}

RIS

TY - JOUR

T1 - Association Between Preoperative Vitamin D Status and Short-Term Physical Performance after Total Hip Arthroplasty

T2 - A Prospective Study

AU - Visser, Edith

AU - de Roos, Nicole M.

AU - Oosting, Ellen

AU - Endenburg, Silvia C.

AU - Dronkers, Jaap J.

N1 - © 2018 The Author(s) Published by S. Karger AG, Basel.

PY - 2018/10

Y1 - 2018/10

N2 - BACKGROUND: Insufficient serum vitamin D concentrations (50-75 nmol/L) are prevalent in 40-65% of patients who require total hip arthroplasty (THA). This could impair physical recovery after surgery. This study investigated the association between preoperative vitamin D status and physical performance after THA. Additionally, postoperative changes in vitamin D concentrations were measured.METHODS: We included 87 patients scheduled for elective THA and aged ≥65 years. Three groups were recruited: patients classified as vitamin D deficient (< 50 nmol/L, n = 23), insufficient (50-75 nmol/L, n = 32), or sufficient (> 75 nmol/L, n = 32). Serum 25-hydroxyvitamin D3 (25[OH]D3) concentration and physical performance were measured perioperatively. Linear mixed models were used to examine differences between groups.RESULTS: Change in physical performance over time was not affected by preoperative vitamin D status. In contrast, for physical activity, both vitamin D (p = 0.021) and time (p < 0.001) effect was seen: from 80.2 ± 25.8 to 58.1 ± 17.8 min/day in the deficient group, 143.7 ± 19.8 to 92.9 ± 11.5 min/day in the insufficient group, and 108.1 ± 20.9 to 62.3 ± 12.9 min/day in the sufficient group. The Chair Stand Test, Timed Up and Go test, and 10-Meter Walking Test also improved significantly over time, but independent of vitamin D status. An increase in 25(OH)D3 concentration 6 weeks postoperatively was correlated with improved hip function (Pearson's r = -0.471, p = 0.018). Overall, serum 25(OH)D3 declined with 32% one day after surgery (p < 0.001), to nearly return to baseline values 6 weeks later in all groups.CONCLUSION: Vitamin D status did not appear to affect physical recovery after THA. The drop in vitamin D after surgery deserves further investigation, but could possibly be explained by hemodilution.

AB - BACKGROUND: Insufficient serum vitamin D concentrations (50-75 nmol/L) are prevalent in 40-65% of patients who require total hip arthroplasty (THA). This could impair physical recovery after surgery. This study investigated the association between preoperative vitamin D status and physical performance after THA. Additionally, postoperative changes in vitamin D concentrations were measured.METHODS: We included 87 patients scheduled for elective THA and aged ≥65 years. Three groups were recruited: patients classified as vitamin D deficient (< 50 nmol/L, n = 23), insufficient (50-75 nmol/L, n = 32), or sufficient (> 75 nmol/L, n = 32). Serum 25-hydroxyvitamin D3 (25[OH]D3) concentration and physical performance were measured perioperatively. Linear mixed models were used to examine differences between groups.RESULTS: Change in physical performance over time was not affected by preoperative vitamin D status. In contrast, for physical activity, both vitamin D (p = 0.021) and time (p < 0.001) effect was seen: from 80.2 ± 25.8 to 58.1 ± 17.8 min/day in the deficient group, 143.7 ± 19.8 to 92.9 ± 11.5 min/day in the insufficient group, and 108.1 ± 20.9 to 62.3 ± 12.9 min/day in the sufficient group. The Chair Stand Test, Timed Up and Go test, and 10-Meter Walking Test also improved significantly over time, but independent of vitamin D status. An increase in 25(OH)D3 concentration 6 weeks postoperatively was correlated with improved hip function (Pearson's r = -0.471, p = 0.018). Overall, serum 25(OH)D3 declined with 32% one day after surgery (p < 0.001), to nearly return to baseline values 6 weeks later in all groups.CONCLUSION: Vitamin D status did not appear to affect physical recovery after THA. The drop in vitamin D after surgery deserves further investigation, but could possibly be explained by hemodilution.

KW - MUSCLE STRENGTH

KW - SKELETAL-MUSCLE

KW - OLDER-ADULTS

KW - D DEFICIENCY

KW - OSTEOARTHRITIS

KW - MOBILITY

KW - POWER

KW - KNEE

KW - SUPPLEMENTATION

KW - METAANALYSIS

U2 - 10.1159/000492938

DO - 10.1159/000492938

M3 - Article

VL - 73

SP - 252

EP - 260

JO - Annals of nutrition and metabolism

JF - Annals of nutrition and metabolism

SN - 0250-6807

IS - 3

ER -

ID: 72237607