Publication

Assessing recovery after cold challenge and thumb involvement can help to rule out systemic sclerosis in patients presenting with Raynaud?s phenomenon

van Roon, A. M., Stel, A. J., Bootsma, H., Smit, A. J. & Mulder, D. J., 23-Oct-2019, In : Scandinavian Journal of Rheumatology. p. 1-4 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

van Roon, A. M., Stel, A. J., Bootsma, H., Smit, A. J., & Mulder, D. J. (2019). Assessing recovery after cold challenge and thumb involvement can help to rule out systemic sclerosis in patients presenting with Raynaud?s phenomenon. Scandinavian Journal of Rheumatology, 1-4. https://doi.org/10.1080/03009742.2019.1643911

Author

van Roon, A M ; Stel, A J ; Bootsma, H ; Smit, A J ; Mulder, D J. / Assessing recovery after cold challenge and thumb involvement can help to rule out systemic sclerosis in patients presenting with Raynaud?s phenomenon. In: Scandinavian Journal of Rheumatology. 2019 ; pp. 1-4.

Harvard

van Roon, AM, Stel, AJ, Bootsma, H, Smit, AJ & Mulder, DJ 2019, 'Assessing recovery after cold challenge and thumb involvement can help to rule out systemic sclerosis in patients presenting with Raynaud?s phenomenon', Scandinavian Journal of Rheumatology, pp. 1-4. https://doi.org/10.1080/03009742.2019.1643911

Standard

Assessing recovery after cold challenge and thumb involvement can help to rule out systemic sclerosis in patients presenting with Raynaud?s phenomenon. / van Roon, A M; Stel, A J; Bootsma, H; Smit, A J; Mulder, D J.

In: Scandinavian Journal of Rheumatology, 23.10.2019, p. 1-4.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

van Roon AM, Stel AJ, Bootsma H, Smit AJ, Mulder DJ. Assessing recovery after cold challenge and thumb involvement can help to rule out systemic sclerosis in patients presenting with Raynaud?s phenomenon. Scandinavian Journal of Rheumatology. 2019 Oct 23;1-4. https://doi.org/10.1080/03009742.2019.1643911


BibTeX

@article{fef7eaedb1234d93957595a78625e628,
title = "Assessing recovery after cold challenge and thumb involvement can help to rule out systemic sclerosis in patients presenting with Raynaud?s phenomenon",
abstract = "Objective: Our aim was to study whether recovery from a Raynaud?s attack and involvement of the thumb are differentiators for systemic sclerosis (SSc) in patients with Raynaud?s phenomenon (RP). Method: A stepwise cooling and recovery procedure was performed, provoking an RP attack, in patients with primary Raynaud?s phenomenon (PRP, n =?68) and SSc (n?=?18). During the procedure, the perfusion of all five fingers during cooling and recovery was assessed by photoelectric plethysmography. Results: In SSc patients, perfusion after 10?min in one or more fingers was more frequently not restored than in PRP patients (p?=?0.001), with a negative predictive value of 98{\%}. The thumb was more frequently involved in SSc patients (p?=?0.036), with a negative predictive value of 95{\%}. Positive predictive values were low. Conclusions: In patients with RP, when there is restoration of perfusion in all fingers after 10?min or when the thumb is spared, the presence of an underlying SSc is very unlikely. Although these results need to be validated in a clinical setting in a larger prospective study, these signs can help physicians to select additional testing for SSc in RP patients.",
keywords = "CRITERIA",
author = "{van Roon}, {A M} and Stel, {A J} and H Bootsma and Smit, {A J} and Mulder, {D J}",
year = "2019",
month = "10",
day = "23",
doi = "10.1080/03009742.2019.1643911",
language = "English",
pages = "1--4",
journal = "Scandinavian Journal of Rheumatology",
issn = "0300-9742",
publisher = "Informa Healthcare",

}

RIS

TY - JOUR

T1 - Assessing recovery after cold challenge and thumb involvement can help to rule out systemic sclerosis in patients presenting with Raynaud?s phenomenon

AU - van Roon, A M

AU - Stel, A J

AU - Bootsma, H

AU - Smit, A J

AU - Mulder, D J

PY - 2019/10/23

Y1 - 2019/10/23

N2 - Objective: Our aim was to study whether recovery from a Raynaud?s attack and involvement of the thumb are differentiators for systemic sclerosis (SSc) in patients with Raynaud?s phenomenon (RP). Method: A stepwise cooling and recovery procedure was performed, provoking an RP attack, in patients with primary Raynaud?s phenomenon (PRP, n =?68) and SSc (n?=?18). During the procedure, the perfusion of all five fingers during cooling and recovery was assessed by photoelectric plethysmography. Results: In SSc patients, perfusion after 10?min in one or more fingers was more frequently not restored than in PRP patients (p?=?0.001), with a negative predictive value of 98%. The thumb was more frequently involved in SSc patients (p?=?0.036), with a negative predictive value of 95%. Positive predictive values were low. Conclusions: In patients with RP, when there is restoration of perfusion in all fingers after 10?min or when the thumb is spared, the presence of an underlying SSc is very unlikely. Although these results need to be validated in a clinical setting in a larger prospective study, these signs can help physicians to select additional testing for SSc in RP patients.

AB - Objective: Our aim was to study whether recovery from a Raynaud?s attack and involvement of the thumb are differentiators for systemic sclerosis (SSc) in patients with Raynaud?s phenomenon (RP). Method: A stepwise cooling and recovery procedure was performed, provoking an RP attack, in patients with primary Raynaud?s phenomenon (PRP, n =?68) and SSc (n?=?18). During the procedure, the perfusion of all five fingers during cooling and recovery was assessed by photoelectric plethysmography. Results: In SSc patients, perfusion after 10?min in one or more fingers was more frequently not restored than in PRP patients (p?=?0.001), with a negative predictive value of 98%. The thumb was more frequently involved in SSc patients (p?=?0.036), with a negative predictive value of 95%. Positive predictive values were low. Conclusions: In patients with RP, when there is restoration of perfusion in all fingers after 10?min or when the thumb is spared, the presence of an underlying SSc is very unlikely. Although these results need to be validated in a clinical setting in a larger prospective study, these signs can help physicians to select additional testing for SSc in RP patients.

KW - CRITERIA

U2 - 10.1080/03009742.2019.1643911

DO - 10.1080/03009742.2019.1643911

M3 - Article

SP - 1

EP - 4

JO - Scandinavian Journal of Rheumatology

JF - Scandinavian Journal of Rheumatology

SN - 0300-9742

ER -

ID: 101573993