Publication

Anemia has a negative impact on self-rated health in kidney transplant recipients with well-functioning grafts: findings from an 8-year follow-up study

Majernikova, M., Rosenberger, J., Prihodova, L., Marcelli, D., Roland, R., Groothoff, J. W. & van Dijk, J. P., Jan-2016, In : Quality of Life Research. 25, 1, p. 183-192 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Majernikova, M., Rosenberger, J., Prihodova, L., Marcelli, D., Roland, R., Groothoff, J. W., & van Dijk, J. P. (2016). Anemia has a negative impact on self-rated health in kidney transplant recipients with well-functioning grafts: findings from an 8-year follow-up study. Quality of Life Research, 25(1), 183-192. https://doi.org/10.1007/s11136-015-1067-7

Author

Majernikova, Maria ; Rosenberger, Jaroslav ; Prihodova, Lucia ; Marcelli, Daniele ; Roland, Robert ; Groothoff, Johan W. ; van Dijk, Jitse P. / Anemia has a negative impact on self-rated health in kidney transplant recipients with well-functioning grafts : findings from an 8-year follow-up study. In: Quality of Life Research. 2016 ; Vol. 25, No. 1. pp. 183-192.

Harvard

Majernikova, M, Rosenberger, J, Prihodova, L, Marcelli, D, Roland, R, Groothoff, JW & van Dijk, JP 2016, 'Anemia has a negative impact on self-rated health in kidney transplant recipients with well-functioning grafts: findings from an 8-year follow-up study', Quality of Life Research, vol. 25, no. 1, pp. 183-192. https://doi.org/10.1007/s11136-015-1067-7

Standard

Anemia has a negative impact on self-rated health in kidney transplant recipients with well-functioning grafts : findings from an 8-year follow-up study. / Majernikova, Maria; Rosenberger, Jaroslav; Prihodova, Lucia; Marcelli, Daniele; Roland, Robert; Groothoff, Johan W.; van Dijk, Jitse P.

In: Quality of Life Research, Vol. 25, No. 1, 01.2016, p. 183-192.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Majernikova M, Rosenberger J, Prihodova L, Marcelli D, Roland R, Groothoff JW et al. Anemia has a negative impact on self-rated health in kidney transplant recipients with well-functioning grafts: findings from an 8-year follow-up study. Quality of Life Research. 2016 Jan;25(1):183-192. https://doi.org/10.1007/s11136-015-1067-7


BibTeX

@article{75398d84f4564f1f947e67ea180897b4,
title = "Anemia has a negative impact on self-rated health in kidney transplant recipients with well-functioning grafts: findings from an 8-year follow-up study",
abstract = "Anemia is a predictor of mortality and of self-rated health (SRH). However, studies on the relationship between SRH and changes in hemoglobin (Hb) value over time stratified by chronic kidney disease (CKD) stages are lacking. The aim is to explore whether a change in Hb-value over time associates with SRH at up to 8-year follow-up, stratified for CKD stages.A prospective study with a baseline measurement between the 3rd and 12th month after KT was performed on 337 consecutive patients. Demographic and clinical data were retrieved from medical records. CKD stages were estimated using the CKD-EPI formula and divided into two groups: CKD1-2 and CKD3-5. Generalized estimating equations (GEE) were performed to identify associations of SRH at follow-up in both CKD groups.Male gender, new-onset diabetes mellitus after KT (NODAT), a decrease in estimated glomerular filtration rate (eGFR) and Hb-value over time contributed significantly to the GEE model on SRH at follow-up in CKD1-2. For SRH at follow-up in CKD3-5, older age, male gender and chronic renal allograft dysfunction (CRAD) contributed significantly to the GEE model.At up to 8-year follow-up, male gender, NODAT, a decrease in eGFR and Hb-value over time are associated with poorer SRH in CKD1-2. In such patients, we suggest monitoring slight deteriorations in eGFR and Hb-values. In CKD3-5, higher age, male gender and higher presence of CRAD are associated with poorer SRH at up to 8-year follow-up. In these patients, adequate treatment would slow down CRAD progression.",
keywords = "Anemia, Chronic kidney disease, Longitudinal design, Self-rated health, Kidney transplantation, QUALITY-OF-LIFE, RENAL-TRANSPLANTATION, REPORTED HEALTH, MORTALITY, PREVALENCE, SF-36, DETERIORATION, MANAGEMENT, DIALYSIS, QUESTION",
author = "Maria Majernikova and Jaroslav Rosenberger and Lucia Prihodova and Daniele Marcelli and Robert Roland and Groothoff, {Johan W.} and {van Dijk}, {Jitse P.}",
year = "2016",
month = "1",
doi = "10.1007/s11136-015-1067-7",
language = "English",
volume = "25",
pages = "183--192",
journal = "Quality of Life Research",
issn = "1573-2649",
publisher = "SPRINGER",
number = "1",

}

RIS

TY - JOUR

T1 - Anemia has a negative impact on self-rated health in kidney transplant recipients with well-functioning grafts

T2 - findings from an 8-year follow-up study

AU - Majernikova, Maria

AU - Rosenberger, Jaroslav

AU - Prihodova, Lucia

AU - Marcelli, Daniele

AU - Roland, Robert

AU - Groothoff, Johan W.

AU - van Dijk, Jitse P.

PY - 2016/1

Y1 - 2016/1

N2 - Anemia is a predictor of mortality and of self-rated health (SRH). However, studies on the relationship between SRH and changes in hemoglobin (Hb) value over time stratified by chronic kidney disease (CKD) stages are lacking. The aim is to explore whether a change in Hb-value over time associates with SRH at up to 8-year follow-up, stratified for CKD stages.A prospective study with a baseline measurement between the 3rd and 12th month after KT was performed on 337 consecutive patients. Demographic and clinical data were retrieved from medical records. CKD stages were estimated using the CKD-EPI formula and divided into two groups: CKD1-2 and CKD3-5. Generalized estimating equations (GEE) were performed to identify associations of SRH at follow-up in both CKD groups.Male gender, new-onset diabetes mellitus after KT (NODAT), a decrease in estimated glomerular filtration rate (eGFR) and Hb-value over time contributed significantly to the GEE model on SRH at follow-up in CKD1-2. For SRH at follow-up in CKD3-5, older age, male gender and chronic renal allograft dysfunction (CRAD) contributed significantly to the GEE model.At up to 8-year follow-up, male gender, NODAT, a decrease in eGFR and Hb-value over time are associated with poorer SRH in CKD1-2. In such patients, we suggest monitoring slight deteriorations in eGFR and Hb-values. In CKD3-5, higher age, male gender and higher presence of CRAD are associated with poorer SRH at up to 8-year follow-up. In these patients, adequate treatment would slow down CRAD progression.

AB - Anemia is a predictor of mortality and of self-rated health (SRH). However, studies on the relationship between SRH and changes in hemoglobin (Hb) value over time stratified by chronic kidney disease (CKD) stages are lacking. The aim is to explore whether a change in Hb-value over time associates with SRH at up to 8-year follow-up, stratified for CKD stages.A prospective study with a baseline measurement between the 3rd and 12th month after KT was performed on 337 consecutive patients. Demographic and clinical data were retrieved from medical records. CKD stages were estimated using the CKD-EPI formula and divided into two groups: CKD1-2 and CKD3-5. Generalized estimating equations (GEE) were performed to identify associations of SRH at follow-up in both CKD groups.Male gender, new-onset diabetes mellitus after KT (NODAT), a decrease in estimated glomerular filtration rate (eGFR) and Hb-value over time contributed significantly to the GEE model on SRH at follow-up in CKD1-2. For SRH at follow-up in CKD3-5, older age, male gender and chronic renal allograft dysfunction (CRAD) contributed significantly to the GEE model.At up to 8-year follow-up, male gender, NODAT, a decrease in eGFR and Hb-value over time are associated with poorer SRH in CKD1-2. In such patients, we suggest monitoring slight deteriorations in eGFR and Hb-values. In CKD3-5, higher age, male gender and higher presence of CRAD are associated with poorer SRH at up to 8-year follow-up. In these patients, adequate treatment would slow down CRAD progression.

KW - Anemia

KW - Chronic kidney disease

KW - Longitudinal design

KW - Self-rated health

KW - Kidney transplantation

KW - QUALITY-OF-LIFE

KW - RENAL-TRANSPLANTATION

KW - REPORTED HEALTH

KW - MORTALITY

KW - PREVALENCE

KW - SF-36

KW - DETERIORATION

KW - MANAGEMENT

KW - DIALYSIS

KW - QUESTION

U2 - 10.1007/s11136-015-1067-7

DO - 10.1007/s11136-015-1067-7

M3 - Article

VL - 25

SP - 183

EP - 192

JO - Quality of Life Research

JF - Quality of Life Research

SN - 1573-2649

IS - 1

ER -

ID: 37947546