Publication

Analysis of physiologic alterations in intensive care unit patients and their relationship with mortality

Rivera-Fernandez, R., Nap, R., Vazquez-Mata, G. & Miranda, D. R., Jun-2007, In : Journal of Critical Care. 22, 2, p. 120-128 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Rivera-Fernandez, R., Nap, R., Vazquez-Mata, G., & Miranda, D. R. (2007). Analysis of physiologic alterations in intensive care unit patients and their relationship with mortality. Journal of Critical Care, 22(2), 120-128. https://doi.org/10.1016/j.jcrc.2006.09.005

Author

Rivera-Fernandez, Ricardo ; Nap, Raoul ; Vazquez-Mata, Guillermo ; Miranda, Dinis Reis. / Analysis of physiologic alterations in intensive care unit patients and their relationship with mortality. In: Journal of Critical Care. 2007 ; Vol. 22, No. 2. pp. 120-128.

Harvard

Rivera-Fernandez, R, Nap, R, Vazquez-Mata, G & Miranda, DR 2007, 'Analysis of physiologic alterations in intensive care unit patients and their relationship with mortality', Journal of Critical Care, vol. 22, no. 2, pp. 120-128. https://doi.org/10.1016/j.jcrc.2006.09.005

Standard

Analysis of physiologic alterations in intensive care unit patients and their relationship with mortality. / Rivera-Fernandez, Ricardo; Nap, Raoul; Vazquez-Mata, Guillermo; Miranda, Dinis Reis.

In: Journal of Critical Care, Vol. 22, No. 2, 06.2007, p. 120-128.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Rivera-Fernandez R, Nap R, Vazquez-Mata G, Miranda DR. Analysis of physiologic alterations in intensive care unit patients and their relationship with mortality. Journal of Critical Care. 2007 Jun;22(2):120-128. https://doi.org/10.1016/j.jcrc.2006.09.005


BibTeX

@article{726e657e5d634a089f6f5bf0791ee3bf,
title = "Analysis of physiologic alterations in intensive care unit patients and their relationship with mortality",
abstract = "Purpose: To analyze patient physiologic alterations (events) and multiple organ failure during intensive care unit (ICU) stay and examine their relationship with ICU mortality.Material and Methods: A total of 17 598 consecutive patients were studied for 10 months (1997-1998) in 55 European ICUs (EURICUS-II). Hourly data were collected on critical and noncritical systolic blood pressure, heart rate, oxygen saturation, and urinary events throughout ICU stay. Sepsis-related Organ Failure Assessment (SOFA) score was collected daily (6409 patients).Results: SAPS-II was 31.2 +/- 18.4 and ICU mortality 13.9{\%}. There were 3.4 +/- 9.2 noncritical (duration, 3.9 +/- 11.4 hours) and 2 +/- 7.5 critical (3.8 +/- 13.1 hours) systolic blood pressure events per patient. Heart rate, oxygen saturation, and urinary events had similar values. Nonsurvivors had significantly more and longer physiologic alterations vs survivors. Mortality was significantly related to mean daily duration of events and mean and maximum daily SOFA. Discrimination capacity to predict ICU mortality was measured using various models: with SAPS 11, area under the receiver operating characteristic curve was 0.80; with APACHE III-classified diagnosis added, 0.84; with mean duration of events/ICU day, 0.91; and with mean and maximum SOFA scores, 0.95.Conclusion: Routinely gathered ICU data on physiologic variables and multiple organ failure can offer considerable complementary information not provided by usual mortality prediction systems; and their weight in daily care policy decisions may need to be revisited. (C) 2007 Elsevier Inc. All rights reserved.",
keywords = "physiologic alterations, ICU patients, mortality, OUTCOME PREDICTION MODELS, III PROGNOSTIC SYSTEM, ADVERSE EVENTS, SCORE, FAILURE, ALARMS, IMPACT, ICU",
author = "Ricardo Rivera-Fernandez and Raoul Nap and Guillermo Vazquez-Mata and Miranda, {Dinis Reis}",
year = "2007",
month = "6",
doi = "10.1016/j.jcrc.2006.09.005",
language = "English",
volume = "22",
pages = "120--128",
journal = "Journal of Critical Care",
issn = "0883-9441",
publisher = "W B SAUNDERS CO-ELSEVIER INC",
number = "2",

}

RIS

TY - JOUR

T1 - Analysis of physiologic alterations in intensive care unit patients and their relationship with mortality

AU - Rivera-Fernandez, Ricardo

AU - Nap, Raoul

AU - Vazquez-Mata, Guillermo

AU - Miranda, Dinis Reis

PY - 2007/6

Y1 - 2007/6

N2 - Purpose: To analyze patient physiologic alterations (events) and multiple organ failure during intensive care unit (ICU) stay and examine their relationship with ICU mortality.Material and Methods: A total of 17 598 consecutive patients were studied for 10 months (1997-1998) in 55 European ICUs (EURICUS-II). Hourly data were collected on critical and noncritical systolic blood pressure, heart rate, oxygen saturation, and urinary events throughout ICU stay. Sepsis-related Organ Failure Assessment (SOFA) score was collected daily (6409 patients).Results: SAPS-II was 31.2 +/- 18.4 and ICU mortality 13.9%. There were 3.4 +/- 9.2 noncritical (duration, 3.9 +/- 11.4 hours) and 2 +/- 7.5 critical (3.8 +/- 13.1 hours) systolic blood pressure events per patient. Heart rate, oxygen saturation, and urinary events had similar values. Nonsurvivors had significantly more and longer physiologic alterations vs survivors. Mortality was significantly related to mean daily duration of events and mean and maximum daily SOFA. Discrimination capacity to predict ICU mortality was measured using various models: with SAPS 11, area under the receiver operating characteristic curve was 0.80; with APACHE III-classified diagnosis added, 0.84; with mean duration of events/ICU day, 0.91; and with mean and maximum SOFA scores, 0.95.Conclusion: Routinely gathered ICU data on physiologic variables and multiple organ failure can offer considerable complementary information not provided by usual mortality prediction systems; and their weight in daily care policy decisions may need to be revisited. (C) 2007 Elsevier Inc. All rights reserved.

AB - Purpose: To analyze patient physiologic alterations (events) and multiple organ failure during intensive care unit (ICU) stay and examine their relationship with ICU mortality.Material and Methods: A total of 17 598 consecutive patients were studied for 10 months (1997-1998) in 55 European ICUs (EURICUS-II). Hourly data were collected on critical and noncritical systolic blood pressure, heart rate, oxygen saturation, and urinary events throughout ICU stay. Sepsis-related Organ Failure Assessment (SOFA) score was collected daily (6409 patients).Results: SAPS-II was 31.2 +/- 18.4 and ICU mortality 13.9%. There were 3.4 +/- 9.2 noncritical (duration, 3.9 +/- 11.4 hours) and 2 +/- 7.5 critical (3.8 +/- 13.1 hours) systolic blood pressure events per patient. Heart rate, oxygen saturation, and urinary events had similar values. Nonsurvivors had significantly more and longer physiologic alterations vs survivors. Mortality was significantly related to mean daily duration of events and mean and maximum daily SOFA. Discrimination capacity to predict ICU mortality was measured using various models: with SAPS 11, area under the receiver operating characteristic curve was 0.80; with APACHE III-classified diagnosis added, 0.84; with mean duration of events/ICU day, 0.91; and with mean and maximum SOFA scores, 0.95.Conclusion: Routinely gathered ICU data on physiologic variables and multiple organ failure can offer considerable complementary information not provided by usual mortality prediction systems; and their weight in daily care policy decisions may need to be revisited. (C) 2007 Elsevier Inc. All rights reserved.

KW - physiologic alterations

KW - ICU patients

KW - mortality

KW - OUTCOME PREDICTION MODELS

KW - III PROGNOSTIC SYSTEM

KW - ADVERSE EVENTS

KW - SCORE

KW - FAILURE

KW - ALARMS

KW - IMPACT

KW - ICU

U2 - 10.1016/j.jcrc.2006.09.005

DO - 10.1016/j.jcrc.2006.09.005

M3 - Article

VL - 22

SP - 120

EP - 128

JO - Journal of Critical Care

JF - Journal of Critical Care

SN - 0883-9441

IS - 2

ER -

ID: 4671336