Allergy-specific immunotherapy compositions for use in the treatment of house-dust mite allergyEuverink, G. J. W., Hesse, L., Nawijn, M. C. & van der Graaf, A. C., 8-Dec-2016, Patent No. WO2016193126, Priority date 29-May-2015
Research output: Patent › Professional
The present invention relates to a composition comprising purified natural Der p1 and purified natural Der p2 allergens for use in the treatment of house-dust mite allergy in mammals, like humans. The invention further pertains pharmaceutical compositions for allergy-specific immune therapy. Specifically, the invention discloses reduced responsiveness to subsequent house dust mite allergen exposure after treatment with a pharmaceutical composition comprising purified natural Der p1 and purified natural Der p2 characterized by reduction in Th2 cell activity and reduction in CCL20 release.
|Publication status||Published - 8-Dec-2016|