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Allergy-specific immunotherapy compositions for use in the treatment of house-dust mite allergy

Euverink, G. J. W., Hesse, L., Nawijn, M. C. & van der Graaf, A. C., 8-Dec-2016, Patent No. WO2016193126, Priority date 29-May-2015

Research output: PatentProfessional

The present invention relates to a composition comprising purified natural Der p1 and purified natural Der p2 allergens for use in the treatment of house-dust mite allergy in mammals, like humans. The invention further pertains pharmaceutical compositions for allergy-specific immune therapy. Specifically, the invention discloses reduced responsiveness to subsequent house dust mite allergen exposure after treatment with a pharmaceutical composition comprising purified natural Der p1 and purified natural Der p2 characterized by reduction in Th2 cell activity and reduction in CCL20 release.
Original languageEnglish
Patent numberWO2016193126
Priority date29/05/2015
Publication statusPublished - 8-Dec-2016

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