Publication

Advances of treatment in atypical cartilaginous tumours

Dierselhuis, E. F., 2019, [Groningen]: Rijksuniversiteit Groningen. 203 p.

Research output: ThesisThesis fully internal (DIV)Academic

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  • Title and contents

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  • Chapter 1

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  • Chapter 2

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  • Chapter 3

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  • Chapter 4

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  • Chapter 5

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  • Chapter 6

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  • Chapter 7

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  • Chapter 8

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  • Chapter 9

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  • Appendices

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  • Complete thesis

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  • Propositions

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  • Edwin Frank Dierselhuis
Atypical cartilaginous tumours (ACT) are tumours arising in bone and mainly only locally aggressive. Over the last decades, treatment of these tumours has become less and less aggressive, in order to prevent unnecessary complications or functional deficits after surgery. This thesis has reviewed the current literature on surgical treatment of these tumours and the results in our own hands. Moreover, we have studied new technical developments
in this field: Computer assisted surgery (CAS) makes real-time navigation during surgery possible, hereby maximizing local precision while minimizing X-ray radiation during the procedure. In addition, we analyzed the application of radiofrequency ablation (RFA) in treatment of ACT in the long bones. The results of this thesis show that scraping out of the tumour is as effective as removal of whole sections of bone. Advantages of this technique is that it has lower complication rates and preserves function better. Results of our own center are comparable to other centers worldwide, in the largest study on these patients to date. CAS has an advantageous role for treatment of ACT, but might be even more of value in more challenging tumours and locations. The use of RFA has resulted in the possibility of treatment in daycare, with even lower complication rates compared to surgery and minimal functional setback after treatment.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
Supervisors/Advisors
Award date10-Jul-2019
Place of Publication[Groningen]
Publisher
Print ISBNs978-90-9031884-4
Publication statusPublished - 2019

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