Publication

Advances of epigenetic editing

Gjaltema, R. A. F. & Rots, M. G., Aug-2020, In : Current Opinion in Chemical Biology. 57, p. 75-81 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

APA

Gjaltema, R. A. F., & Rots, M. G. (2020). Advances of epigenetic editing. Current Opinion in Chemical Biology, 57, 75-81. https://doi.org/10.1016/j.cbpa.2020.04.020

Author

Gjaltema, Rutger A F ; Rots, Marianne G. / Advances of epigenetic editing. In: Current Opinion in Chemical Biology. 2020 ; Vol. 57. pp. 75-81.

Harvard

Gjaltema, RAF & Rots, MG 2020, 'Advances of epigenetic editing', Current Opinion in Chemical Biology, vol. 57, pp. 75-81. https://doi.org/10.1016/j.cbpa.2020.04.020

Standard

Advances of epigenetic editing. / Gjaltema, Rutger A F; Rots, Marianne G.

In: Current Opinion in Chemical Biology, Vol. 57, 08.2020, p. 75-81.

Research output: Contribution to journalReview articleAcademicpeer-review

Vancouver

Gjaltema RAF, Rots MG. Advances of epigenetic editing. Current Opinion in Chemical Biology. 2020 Aug;57:75-81. https://doi.org/10.1016/j.cbpa.2020.04.020


BibTeX

@article{c77b79cd26e148d8b2b7309893d3c66b,
title = "Advances of epigenetic editing",
abstract = "Epigenetic editing refers to the locus-specific targeting of epigenetic enzymes to rewrite the local epigenetic landscape of an endogenous genomic site, often with the aim of transcriptional reprogramming. Implementing clustered regularly interspaced short palindromic repeat-dCas9 greatly accelerated the advancement of epigenetic editing, yielding preclinical therapeutic successes using a variety of epigenetic enzymes. ,CRISPR/dCas9 Here, were review the current applications of these epigenetic editing tools in mammalians and shed light on biochemical improvements that facilitate versatile applications.",
author = "Gjaltema, {Rutger A F} and Rots, {Marianne G}",
note = "Copyright {\circledC} 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.",
year = "2020",
month = "8",
doi = "10.1016/j.cbpa.2020.04.020",
language = "English",
volume = "57",
pages = "75--81",
journal = "Current Opinion in Chemical Biology",
issn = "1367-5931",
publisher = "ELSEVIER SCI LTD",

}

RIS

TY - JOUR

T1 - Advances of epigenetic editing

AU - Gjaltema, Rutger A F

AU - Rots, Marianne G

N1 - Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.

PY - 2020/8

Y1 - 2020/8

N2 - Epigenetic editing refers to the locus-specific targeting of epigenetic enzymes to rewrite the local epigenetic landscape of an endogenous genomic site, often with the aim of transcriptional reprogramming. Implementing clustered regularly interspaced short palindromic repeat-dCas9 greatly accelerated the advancement of epigenetic editing, yielding preclinical therapeutic successes using a variety of epigenetic enzymes. ,CRISPR/dCas9 Here, were review the current applications of these epigenetic editing tools in mammalians and shed light on biochemical improvements that facilitate versatile applications.

AB - Epigenetic editing refers to the locus-specific targeting of epigenetic enzymes to rewrite the local epigenetic landscape of an endogenous genomic site, often with the aim of transcriptional reprogramming. Implementing clustered regularly interspaced short palindromic repeat-dCas9 greatly accelerated the advancement of epigenetic editing, yielding preclinical therapeutic successes using a variety of epigenetic enzymes. ,CRISPR/dCas9 Here, were review the current applications of these epigenetic editing tools in mammalians and shed light on biochemical improvements that facilitate versatile applications.

U2 - 10.1016/j.cbpa.2020.04.020

DO - 10.1016/j.cbpa.2020.04.020

M3 - Review article

C2 - 32619853

VL - 57

SP - 75

EP - 81

JO - Current Opinion in Chemical Biology

JF - Current Opinion in Chemical Biology

SN - 1367-5931

ER -

ID: 128811640