Publication

Adenotonsillectomy or watchful waiting in patients with mild to moderate symptoms of throat infections or adenotonsillar hypertrophy - A Randomized comparison of costs and effects

Buskens, E., van Staaij, B., van den Akker, J., Hoes, A. W. & Schilder, A. G. M., Nov-2007, In : ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY. 133, 11, p. 1083-1088 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Buskens, E., van Staaij, B., van den Akker, J., Hoes, A. W., & Schilder, A. G. M. (2007). Adenotonsillectomy or watchful waiting in patients with mild to moderate symptoms of throat infections or adenotonsillar hypertrophy - A Randomized comparison of costs and effects. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 133(11), 1083-1088.

Author

Buskens, Erik ; van Staaij, Birgit ; van den Akker, Jet ; Hoes, Arno W. ; Schilder, Anne G. M. / Adenotonsillectomy or watchful waiting in patients with mild to moderate symptoms of throat infections or adenotonsillar hypertrophy - A Randomized comparison of costs and effects. In: ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY. 2007 ; Vol. 133, No. 11. pp. 1083-1088.

Harvard

Buskens, E, van Staaij, B, van den Akker, J, Hoes, AW & Schilder, AGM 2007, 'Adenotonsillectomy or watchful waiting in patients with mild to moderate symptoms of throat infections or adenotonsillar hypertrophy - A Randomized comparison of costs and effects', ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, vol. 133, no. 11, pp. 1083-1088.

Standard

Adenotonsillectomy or watchful waiting in patients with mild to moderate symptoms of throat infections or adenotonsillar hypertrophy - A Randomized comparison of costs and effects. / Buskens, Erik; van Staaij, Birgit; van den Akker, Jet; Hoes, Arno W.; Schilder, Anne G. M.

In: ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, Vol. 133, No. 11, 11.2007, p. 1083-1088.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Buskens E, van Staaij B, van den Akker J, Hoes AW, Schilder AGM. Adenotonsillectomy or watchful waiting in patients with mild to moderate symptoms of throat infections or adenotonsillar hypertrophy - A Randomized comparison of costs and effects. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY. 2007 Nov;133(11):1083-1088.


BibTeX

@article{fde0568a2fc34fe0845d2235c25a02c8,
title = "Adenotonsillectomy or watchful waiting in patients with mild to moderate symptoms of throat infections or adenotonsillar hypertrophy - A Randomized comparison of costs and effects",
abstract = "Objective: To evaluate the cost-effectiveness of adenotonsillectomy compared with watchful waiting in Dutch children.Design: Economic evaluation along with an open, randomized, controlled trial.Setting: Multicenter, including 21 general and 3 university hospitals in the Netherlands.Participants: Three hundred children aged 2 to 8 years were selected for adenotonsillectomy according to routine medical practice. Excluded were children who had frequent throat infections and those with suspected obstructive sleep apnea.Main Outcome Measures: Incremental cost-effectiveness in terms of costs per episode of fever, throat infection, and upper respiratory tract infection avoided.Results: Annual costs incurred in the adenotonsillectomy group were is an element of 803 (the average exchange rate for the US dollar in 2002 was $1.00 = is an element of 1.1, except toward the end of 2002 when $0.95 =is an element of 100) and is an element of 551. in the watchful waiting group (46{\%} increase). During a median follow-up of 22 months, surgery compared with watchful waiting reduced the number of episodes of fever and throat infections by 0.21 per person-year (95{\%} confidence interval, -0.12 to 0.54 and 0.06 to 0.36, respectively) and upper respiratory tract infections by 0.53 (95{\%} confidence interval, 0.08 to 0.97) episodes. The incremental costs per episode avoided were is an element of 1136, is an element of 1187, and is an element of 465; respectively.Conclusions: In children undergoing adenotonsillectomy because of mild to moderate symptoms of throat infections or adenotonsillar hypertrophy, surgery resulted in a significant increase in costs without realizing relevant clinical benefit. Subgroups of children in whom surgery would be cost-effective may be identified in further research.",
keywords = "OBSTRUCTIVE SLEEP-APNEA, CHILDREN, (ADENO)TONSILLECTOMY, TONSILLECTOMY",
author = "Erik Buskens and {van Staaij}, Birgit and {van den Akker}, Jet and Hoes, {Arno W.} and Schilder, {Anne G. M.}",
year = "2007",
month = "11",
language = "English",
volume = "133",
pages = "1083--1088",
journal = "ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY",
issn = "0886-4470",
publisher = "AMER MEDICAL ASSOC",
number = "11",

}

RIS

TY - JOUR

T1 - Adenotonsillectomy or watchful waiting in patients with mild to moderate symptoms of throat infections or adenotonsillar hypertrophy - A Randomized comparison of costs and effects

AU - Buskens, Erik

AU - van Staaij, Birgit

AU - van den Akker, Jet

AU - Hoes, Arno W.

AU - Schilder, Anne G. M.

PY - 2007/11

Y1 - 2007/11

N2 - Objective: To evaluate the cost-effectiveness of adenotonsillectomy compared with watchful waiting in Dutch children.Design: Economic evaluation along with an open, randomized, controlled trial.Setting: Multicenter, including 21 general and 3 university hospitals in the Netherlands.Participants: Three hundred children aged 2 to 8 years were selected for adenotonsillectomy according to routine medical practice. Excluded were children who had frequent throat infections and those with suspected obstructive sleep apnea.Main Outcome Measures: Incremental cost-effectiveness in terms of costs per episode of fever, throat infection, and upper respiratory tract infection avoided.Results: Annual costs incurred in the adenotonsillectomy group were is an element of 803 (the average exchange rate for the US dollar in 2002 was $1.00 = is an element of 1.1, except toward the end of 2002 when $0.95 =is an element of 100) and is an element of 551. in the watchful waiting group (46% increase). During a median follow-up of 22 months, surgery compared with watchful waiting reduced the number of episodes of fever and throat infections by 0.21 per person-year (95% confidence interval, -0.12 to 0.54 and 0.06 to 0.36, respectively) and upper respiratory tract infections by 0.53 (95% confidence interval, 0.08 to 0.97) episodes. The incremental costs per episode avoided were is an element of 1136, is an element of 1187, and is an element of 465; respectively.Conclusions: In children undergoing adenotonsillectomy because of mild to moderate symptoms of throat infections or adenotonsillar hypertrophy, surgery resulted in a significant increase in costs without realizing relevant clinical benefit. Subgroups of children in whom surgery would be cost-effective may be identified in further research.

AB - Objective: To evaluate the cost-effectiveness of adenotonsillectomy compared with watchful waiting in Dutch children.Design: Economic evaluation along with an open, randomized, controlled trial.Setting: Multicenter, including 21 general and 3 university hospitals in the Netherlands.Participants: Three hundred children aged 2 to 8 years were selected for adenotonsillectomy according to routine medical practice. Excluded were children who had frequent throat infections and those with suspected obstructive sleep apnea.Main Outcome Measures: Incremental cost-effectiveness in terms of costs per episode of fever, throat infection, and upper respiratory tract infection avoided.Results: Annual costs incurred in the adenotonsillectomy group were is an element of 803 (the average exchange rate for the US dollar in 2002 was $1.00 = is an element of 1.1, except toward the end of 2002 when $0.95 =is an element of 100) and is an element of 551. in the watchful waiting group (46% increase). During a median follow-up of 22 months, surgery compared with watchful waiting reduced the number of episodes of fever and throat infections by 0.21 per person-year (95% confidence interval, -0.12 to 0.54 and 0.06 to 0.36, respectively) and upper respiratory tract infections by 0.53 (95% confidence interval, 0.08 to 0.97) episodes. The incremental costs per episode avoided were is an element of 1136, is an element of 1187, and is an element of 465; respectively.Conclusions: In children undergoing adenotonsillectomy because of mild to moderate symptoms of throat infections or adenotonsillar hypertrophy, surgery resulted in a significant increase in costs without realizing relevant clinical benefit. Subgroups of children in whom surgery would be cost-effective may be identified in further research.

KW - OBSTRUCTIVE SLEEP-APNEA

KW - CHILDREN

KW - (ADENO)TONSILLECTOMY

KW - TONSILLECTOMY

M3 - Article

VL - 133

SP - 1083

EP - 1088

JO - ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY

JF - ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY

SN - 0886-4470

IS - 11

ER -

ID: 4643021