Publication

Absence of a specific subgingival microflora in adults with Down's syndrome

Reuland-Bosma, W., van der Reijden, WA. & van Winkelhoff, AJ., Nov-2001, In : Journal of Clinical Periodontology. 28, 11, p. 1004-1009 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Reuland-Bosma, W., van der Reijden, WA., & van Winkelhoff, AJ. (2001). Absence of a specific subgingival microflora in adults with Down's syndrome. Journal of Clinical Periodontology, 28(11), 1004-1009.

Author

Reuland-Bosma, W ; van der Reijden, WA ; van Winkelhoff, AJ. / Absence of a specific subgingival microflora in adults with Down's syndrome. In: Journal of Clinical Periodontology. 2001 ; Vol. 28, No. 11. pp. 1004-1009.

Harvard

Reuland-Bosma, W, van der Reijden, WA & van Winkelhoff, AJ 2001, 'Absence of a specific subgingival microflora in adults with Down's syndrome', Journal of Clinical Periodontology, vol. 28, no. 11, pp. 1004-1009.

Standard

Absence of a specific subgingival microflora in adults with Down's syndrome. / Reuland-Bosma, W; van der Reijden, WA; van Winkelhoff, AJ.

In: Journal of Clinical Periodontology, Vol. 28, No. 11, 11.2001, p. 1004-1009.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Reuland-Bosma W, van der Reijden WA, van Winkelhoff AJ. Absence of a specific subgingival microflora in adults with Down's syndrome. Journal of Clinical Periodontology. 2001 Nov;28(11):1004-1009.


BibTeX

@article{3d63f22e3aca4e8cbc249ddf81f28605,
title = "Absence of a specific subgingival microflora in adults with Down's syndrome",
abstract = "Background: Periodontal disease in Down's syndrome (DS) is generally characterized by a high degree of bone loss. Bone loss of 5 mm or more is observed in 70% of these subjects. Among DS subjects, considerable differences in disease progression occur. So far, no studies have been conducted in which specific properties of the subgingival microflora have been related to the condition observed.Aims: To investigate (1) the subgingival microflora in DS subjects and other mentally retarded (control) individuals which were matched to the utmost and (2) to investigate the subgingival microflora of a {"}low-risk{"} and a {"}high-risk{"} group formed in DS subjects.Material and Methods: 17 DS subjects and 17 control subjects were matched with respect to age, plaque level and bleeding on probing. In addition, the DS group was divided in a {"}low-risk{"} group (0-2 teeth lost due to periodontal disease n = 6) and a {"}high-risk{"} group (6-13 teeth lost due to periodontal disease n = 11). Prevalence and proportions of the putative periodontal pathogens Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Bacteroides forsythus, Peptostreptococcus micros, Fusobacterium nucleation and Campylobacter rectus in the subgingival plaque were determined using anaerobic culture techniques. No differences in the prevalence of distinct suspected periodontopathic bacteria and bacterial subgingival composition between the DS group and the control group could be established. Also no differences in the prevalence of the seven investigated microbial species between the {"}low-risk{"} and the {"}high-risk{"} group were observed.Conclusions: Because of the lack of differences in microflora between the DS group and the control group, a specific effect of the microbiological composition in the periodontal status of subjects with DS can be excluded in this population. Host factors constitute the more likely explanation of the differences observed in DS.",
keywords = "Down's syndrome, periodontal disease, periodontal pathogens, ACTINOBACILLUS-ACTINOMYCETEMCOMITANS, PERIODONTAL-DISEASE, CHILDREN, GINGIVALIS, ADOLESCENTS, PREVALENCE, POPULATION, GINGIVITIS, BACTERIA, PLAQUE",
author = "W Reuland-Bosma and {van der Reijden}, WA and {van Winkelhoff}, AJ",
year = "2001",
month = nov,
language = "English",
volume = "28",
pages = "1004--1009",
journal = "Journal of Clinical Periodontology",
issn = "0303-6979",
publisher = "Wiley",
number = "11",

}

RIS

TY - JOUR

T1 - Absence of a specific subgingival microflora in adults with Down's syndrome

AU - Reuland-Bosma, W

AU - van der Reijden, WA

AU - van Winkelhoff, AJ

PY - 2001/11

Y1 - 2001/11

N2 - Background: Periodontal disease in Down's syndrome (DS) is generally characterized by a high degree of bone loss. Bone loss of 5 mm or more is observed in 70% of these subjects. Among DS subjects, considerable differences in disease progression occur. So far, no studies have been conducted in which specific properties of the subgingival microflora have been related to the condition observed.Aims: To investigate (1) the subgingival microflora in DS subjects and other mentally retarded (control) individuals which were matched to the utmost and (2) to investigate the subgingival microflora of a "low-risk" and a "high-risk" group formed in DS subjects.Material and Methods: 17 DS subjects and 17 control subjects were matched with respect to age, plaque level and bleeding on probing. In addition, the DS group was divided in a "low-risk" group (0-2 teeth lost due to periodontal disease n = 6) and a "high-risk" group (6-13 teeth lost due to periodontal disease n = 11). Prevalence and proportions of the putative periodontal pathogens Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Bacteroides forsythus, Peptostreptococcus micros, Fusobacterium nucleation and Campylobacter rectus in the subgingival plaque were determined using anaerobic culture techniques. No differences in the prevalence of distinct suspected periodontopathic bacteria and bacterial subgingival composition between the DS group and the control group could be established. Also no differences in the prevalence of the seven investigated microbial species between the "low-risk" and the "high-risk" group were observed.Conclusions: Because of the lack of differences in microflora between the DS group and the control group, a specific effect of the microbiological composition in the periodontal status of subjects with DS can be excluded in this population. Host factors constitute the more likely explanation of the differences observed in DS.

AB - Background: Periodontal disease in Down's syndrome (DS) is generally characterized by a high degree of bone loss. Bone loss of 5 mm or more is observed in 70% of these subjects. Among DS subjects, considerable differences in disease progression occur. So far, no studies have been conducted in which specific properties of the subgingival microflora have been related to the condition observed.Aims: To investigate (1) the subgingival microflora in DS subjects and other mentally retarded (control) individuals which were matched to the utmost and (2) to investigate the subgingival microflora of a "low-risk" and a "high-risk" group formed in DS subjects.Material and Methods: 17 DS subjects and 17 control subjects were matched with respect to age, plaque level and bleeding on probing. In addition, the DS group was divided in a "low-risk" group (0-2 teeth lost due to periodontal disease n = 6) and a "high-risk" group (6-13 teeth lost due to periodontal disease n = 11). Prevalence and proportions of the putative periodontal pathogens Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Bacteroides forsythus, Peptostreptococcus micros, Fusobacterium nucleation and Campylobacter rectus in the subgingival plaque were determined using anaerobic culture techniques. No differences in the prevalence of distinct suspected periodontopathic bacteria and bacterial subgingival composition between the DS group and the control group could be established. Also no differences in the prevalence of the seven investigated microbial species between the "low-risk" and the "high-risk" group were observed.Conclusions: Because of the lack of differences in microflora between the DS group and the control group, a specific effect of the microbiological composition in the periodontal status of subjects with DS can be excluded in this population. Host factors constitute the more likely explanation of the differences observed in DS.

KW - Down's syndrome

KW - periodontal disease

KW - periodontal pathogens

KW - ACTINOBACILLUS-ACTINOMYCETEMCOMITANS

KW - PERIODONTAL-DISEASE

KW - CHILDREN

KW - GINGIVALIS

KW - ADOLESCENTS

KW - PREVALENCE

KW - POPULATION

KW - GINGIVITIS

KW - BACTERIA

KW - PLAQUE

M3 - Article

VL - 28

SP - 1004

EP - 1009

JO - Journal of Clinical Periodontology

JF - Journal of Clinical Periodontology

SN - 0303-6979

IS - 11

ER -

ID: 13928513