Publication

A multinational observational study identifying primary care patients at risk of overestimation of asthma control

Kritikos, V., Price, D., Papi, A., Infantino, A., Ställberg, B., Ryan, D., Lavorini, F., Chrystyn, H., Haughney, J., Lisspers, K., Gruffydd-Jones, K., Román Rodríguez, M., Høegh Henrichsen, S., van der Molen, T., Carter, V. & Bosnic-Anticevich, S., 5-Dec-2019, In : npj Primary Care Respiratory Medicine. 29, 1, 9 p., 43.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Kritikos, V., Price, D., Papi, A., Infantino, A., Ställberg, B., Ryan, D., ... Bosnic-Anticevich, S. (2019). A multinational observational study identifying primary care patients at risk of overestimation of asthma control. npj Primary Care Respiratory Medicine, 29(1), [43]. https://doi.org/10.1038/s41533-019-0156-4

Author

Kritikos, Vicky ; Price, David ; Papi, Alberto ; Infantino, Antonio ; Ställberg, Bjorn ; Ryan, Dermot ; Lavorini, Federico ; Chrystyn, Henry ; Haughney, John ; Lisspers, Karin ; Gruffydd-Jones, Kevin ; Román Rodríguez, Miguel ; Høegh Henrichsen, Svein ; van der Molen, Thys ; Carter, Victoria ; Bosnic-Anticevich, Sinthia. / A multinational observational study identifying primary care patients at risk of overestimation of asthma control. In: npj Primary Care Respiratory Medicine. 2019 ; Vol. 29, No. 1.

Harvard

Kritikos, V, Price, D, Papi, A, Infantino, A, Ställberg, B, Ryan, D, Lavorini, F, Chrystyn, H, Haughney, J, Lisspers, K, Gruffydd-Jones, K, Román Rodríguez, M, Høegh Henrichsen, S, van der Molen, T, Carter, V & Bosnic-Anticevich, S 2019, 'A multinational observational study identifying primary care patients at risk of overestimation of asthma control', npj Primary Care Respiratory Medicine, vol. 29, no. 1, 43. https://doi.org/10.1038/s41533-019-0156-4

Standard

A multinational observational study identifying primary care patients at risk of overestimation of asthma control. / Kritikos, Vicky; Price, David; Papi, Alberto; Infantino, Antonio; Ställberg, Bjorn; Ryan, Dermot; Lavorini, Federico; Chrystyn, Henry; Haughney, John; Lisspers, Karin; Gruffydd-Jones, Kevin; Román Rodríguez, Miguel; Høegh Henrichsen, Svein; van der Molen, Thys; Carter, Victoria; Bosnic-Anticevich, Sinthia.

In: npj Primary Care Respiratory Medicine, Vol. 29, No. 1, 43, 05.12.2019.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Kritikos V, Price D, Papi A, Infantino A, Ställberg B, Ryan D et al. A multinational observational study identifying primary care patients at risk of overestimation of asthma control. npj Primary Care Respiratory Medicine. 2019 Dec 5;29(1). 43. https://doi.org/10.1038/s41533-019-0156-4


BibTeX

@article{2ffa79b40a96437eb7bbe424e6cd080d,
title = "A multinational observational study identifying primary care patients at risk of overestimation of asthma control",
abstract = "Factors related to the discrepancy between patient-perceived and actual disease control remain unclear. Identifying patients at risk of overestimation of asthma control remains elusive. This study aimed to (i) investigate the relationship between patient-reported and actual level of asthma control (ii), compare the characteristics between patients who believe their asthma is well controlled that accurately report 'well-controlled' asthma with those that do not, and (iii) identify factors associated with inaccurately reported 'well-controlled' asthma. A historical, multinational, cross-sectional study using data from the iHARP (initiative Helping Asthma in Real-life Patients) review service for adults with asthma prescribed fixed-dose combination therapy. Data from 4274 patients were analysed. A major discrepancy between patient-reported and Global Initiative for Asthma defined asthma control was detected; 71.1{\%} of patients who reported 'well-controlled' asthma were inaccurate in their perception despite receiving regular maintenance therapy. Significant differences were noted in age, gender, body mass index, education level, medication use, side effects, attitudes to preventer inhaler use, inhaler technique review and respiratory specialist review between patients who accurately reported 'wellcontrolled' asthma and those who did not. Independent risk factors associated with inaccurately reported 'well-controlled' asthma were: having taken a maximum of 5-12 puffs or more of reliever inhaler on at least one day within the previous 4 weeks; being female; having seen a respiratory specialist more than a year ago (rather than in the previous year); and having required oral corticosteroids for worsening asthma in the previous year. The study highlighted the significant hidden burden associated with under-recognition of poor asthma control, on the part of the patient and the need for targeted interventions designed to address the continuing discrepancy between perceived and actual disease control.",
keywords = "INHALER ERRORS, MANAGEMENT, ASSOCIATION, PERCEPTIONS, INSIGHT, EUROPE, MORTALITY, COUNTRIES, BELIEFS, EVENTS",
author = "Vicky Kritikos and David Price and Alberto Papi and Antonio Infantino and Bjorn St{\"a}llberg and Dermot Ryan and Federico Lavorini and Henry Chrystyn and John Haughney and Karin Lisspers and Kevin Gruffydd-Jones and {Rom{\'a}n Rodr{\'i}guez}, Miguel and {H{\o}egh Henrichsen}, Svein and {van der Molen}, Thys and Victoria Carter and Sinthia Bosnic-Anticevich",
year = "2019",
month = "12",
day = "5",
doi = "10.1038/s41533-019-0156-4",
language = "English",
volume = "29",
journal = "npj Primary Care Respiratory Medicine",
issn = "2055-1010",
publisher = "SPRINGERNATURE",
number = "1",

}

RIS

TY - JOUR

T1 - A multinational observational study identifying primary care patients at risk of overestimation of asthma control

AU - Kritikos, Vicky

AU - Price, David

AU - Papi, Alberto

AU - Infantino, Antonio

AU - Ställberg, Bjorn

AU - Ryan, Dermot

AU - Lavorini, Federico

AU - Chrystyn, Henry

AU - Haughney, John

AU - Lisspers, Karin

AU - Gruffydd-Jones, Kevin

AU - Román Rodríguez, Miguel

AU - Høegh Henrichsen, Svein

AU - van der Molen, Thys

AU - Carter, Victoria

AU - Bosnic-Anticevich, Sinthia

PY - 2019/12/5

Y1 - 2019/12/5

N2 - Factors related to the discrepancy between patient-perceived and actual disease control remain unclear. Identifying patients at risk of overestimation of asthma control remains elusive. This study aimed to (i) investigate the relationship between patient-reported and actual level of asthma control (ii), compare the characteristics between patients who believe their asthma is well controlled that accurately report 'well-controlled' asthma with those that do not, and (iii) identify factors associated with inaccurately reported 'well-controlled' asthma. A historical, multinational, cross-sectional study using data from the iHARP (initiative Helping Asthma in Real-life Patients) review service for adults with asthma prescribed fixed-dose combination therapy. Data from 4274 patients were analysed. A major discrepancy between patient-reported and Global Initiative for Asthma defined asthma control was detected; 71.1% of patients who reported 'well-controlled' asthma were inaccurate in their perception despite receiving regular maintenance therapy. Significant differences were noted in age, gender, body mass index, education level, medication use, side effects, attitudes to preventer inhaler use, inhaler technique review and respiratory specialist review between patients who accurately reported 'wellcontrolled' asthma and those who did not. Independent risk factors associated with inaccurately reported 'well-controlled' asthma were: having taken a maximum of 5-12 puffs or more of reliever inhaler on at least one day within the previous 4 weeks; being female; having seen a respiratory specialist more than a year ago (rather than in the previous year); and having required oral corticosteroids for worsening asthma in the previous year. The study highlighted the significant hidden burden associated with under-recognition of poor asthma control, on the part of the patient and the need for targeted interventions designed to address the continuing discrepancy between perceived and actual disease control.

AB - Factors related to the discrepancy between patient-perceived and actual disease control remain unclear. Identifying patients at risk of overestimation of asthma control remains elusive. This study aimed to (i) investigate the relationship between patient-reported and actual level of asthma control (ii), compare the characteristics between patients who believe their asthma is well controlled that accurately report 'well-controlled' asthma with those that do not, and (iii) identify factors associated with inaccurately reported 'well-controlled' asthma. A historical, multinational, cross-sectional study using data from the iHARP (initiative Helping Asthma in Real-life Patients) review service for adults with asthma prescribed fixed-dose combination therapy. Data from 4274 patients were analysed. A major discrepancy between patient-reported and Global Initiative for Asthma defined asthma control was detected; 71.1% of patients who reported 'well-controlled' asthma were inaccurate in their perception despite receiving regular maintenance therapy. Significant differences were noted in age, gender, body mass index, education level, medication use, side effects, attitudes to preventer inhaler use, inhaler technique review and respiratory specialist review between patients who accurately reported 'wellcontrolled' asthma and those who did not. Independent risk factors associated with inaccurately reported 'well-controlled' asthma were: having taken a maximum of 5-12 puffs or more of reliever inhaler on at least one day within the previous 4 weeks; being female; having seen a respiratory specialist more than a year ago (rather than in the previous year); and having required oral corticosteroids for worsening asthma in the previous year. The study highlighted the significant hidden burden associated with under-recognition of poor asthma control, on the part of the patient and the need for targeted interventions designed to address the continuing discrepancy between perceived and actual disease control.

KW - INHALER ERRORS

KW - MANAGEMENT

KW - ASSOCIATION

KW - PERCEPTIONS

KW - INSIGHT

KW - EUROPE

KW - MORTALITY

KW - COUNTRIES

KW - BELIEFS

KW - EVENTS

U2 - 10.1038/s41533-019-0156-4

DO - 10.1038/s41533-019-0156-4

M3 - Article

C2 - 31804501

VL - 29

JO - npj Primary Care Respiratory Medicine

JF - npj Primary Care Respiratory Medicine

SN - 2055-1010

IS - 1

M1 - 43

ER -

ID: 108343582