Publication

A multicentre study of air pollution exposure and childhood asthma prevalence: the ESCAPE project

Moelter, A., Simpson, A., Berdel, D., Brunekreef, B., Custovic, A., Cyrys, J., de Jongste, J., de Vocht, F., Fuertes, E., Gehring, U., Gruzieva, O., Heinrich, J., Hoek, G., Hoffmann, B., Kluemper, C., Korek, M., Kuhlbusch, T. A. J., Lindley, S., Postma, D., Tischer, C., Wijga, A., Pershagen, G. & Agius, R., Mar-2015, In : European Respiratory Journal. 45, 3, p. 610-624 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Moelter, A., Simpson, A., Berdel, D., Brunekreef, B., Custovic, A., Cyrys, J., ... Agius, R. (2015). A multicentre study of air pollution exposure and childhood asthma prevalence: the ESCAPE project. European Respiratory Journal, 45(3), 610-624. https://doi.org/10.1183/09031936.00083614

Author

Moelter, Anna ; Simpson, Angela ; Berdel, Dietrich ; Brunekreef, Bert ; Custovic, Adnan ; Cyrys, Josef ; de Jongste, Johan ; de Vocht, Frank ; Fuertes, Elaine ; Gehring, Ulrike ; Gruzieva, Olena ; Heinrich, Joachim ; Hoek, Gerard ; Hoffmann, Barbara ; Kluemper, Claudia ; Korek, Michal ; Kuhlbusch, Thomas A. J. ; Lindley, Sarah ; Postma, Dirkje ; Tischer, Christina ; Wijga, Alet ; Pershagen, Goran ; Agius, Raymond. / A multicentre study of air pollution exposure and childhood asthma prevalence : the ESCAPE project. In: European Respiratory Journal. 2015 ; Vol. 45, No. 3. pp. 610-624.

Harvard

Moelter, A, Simpson, A, Berdel, D, Brunekreef, B, Custovic, A, Cyrys, J, de Jongste, J, de Vocht, F, Fuertes, E, Gehring, U, Gruzieva, O, Heinrich, J, Hoek, G, Hoffmann, B, Kluemper, C, Korek, M, Kuhlbusch, TAJ, Lindley, S, Postma, D, Tischer, C, Wijga, A, Pershagen, G & Agius, R 2015, 'A multicentre study of air pollution exposure and childhood asthma prevalence: the ESCAPE project' European Respiratory Journal, vol. 45, no. 3, pp. 610-624. https://doi.org/10.1183/09031936.00083614

Standard

A multicentre study of air pollution exposure and childhood asthma prevalence : the ESCAPE project. / Moelter, Anna; Simpson, Angela; Berdel, Dietrich; Brunekreef, Bert; Custovic, Adnan; Cyrys, Josef; de Jongste, Johan; de Vocht, Frank; Fuertes, Elaine; Gehring, Ulrike; Gruzieva, Olena; Heinrich, Joachim; Hoek, Gerard; Hoffmann, Barbara; Kluemper, Claudia; Korek, Michal; Kuhlbusch, Thomas A. J.; Lindley, Sarah; Postma, Dirkje; Tischer, Christina; Wijga, Alet; Pershagen, Goran; Agius, Raymond.

In: European Respiratory Journal, Vol. 45, No. 3, 03.2015, p. 610-624.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Moelter A, Simpson A, Berdel D, Brunekreef B, Custovic A, Cyrys J et al. A multicentre study of air pollution exposure and childhood asthma prevalence: the ESCAPE project. European Respiratory Journal. 2015 Mar;45(3):610-624. https://doi.org/10.1183/09031936.00083614


BibTeX

@article{b4371c1025044faa932e61c2b75865c8,
title = "A multicentre study of air pollution exposure and childhood asthma prevalence: the ESCAPE project",
abstract = "The aim of this study was to determine the effect of six traffic-related air pollution metrics (nitrogen dioxide, nitrogen oxides, particulate matter with an aerodynamic diameterLand-use regression models were developed for each study area and used to estimate outdoor air pollution exposure at the home address of each child. Information on asthma and current wheeze prevalence at the ages of 4-5 and 8-10 years was collected using validated questionnaires. Multiple logistic regression was used to analyse the association between pollutant exposure and asthma within each cohort. Random-effects meta-analyses were used to combine effect estimates from individual cohorts.The meta-analyses showed no significant association between asthma prevalence and air pollution exposure (e.g. adjusted OR (95{\%}CI) for asthma at age 8-10 years and exposure at the birth address (n=10377): 1.10 (0.81-1.49) per 10 mu g.m(-3) nitrogen dioxide; 0.88 (0.63-1.24) per 10 mu g.m(-3) PM10; 1.23 (0.78-1.95) per 5 mu g.m(-3) PM2.5). This result was consistently found in initial crude models, adjusted models and further sensitivity analyses.This study found no significant association between air pollution exposure and childhood asthma prevalence in five European birth cohorts.",
keywords = "USE REGRESSION-MODELS, CHILDRENS RESPIRATORY SYMPTOMS, LONG-TERM EXPOSURE, BIRTH COHORT, NITROGEN-DIOXIDE, PARTICULATE MATTER, PM2.5 ABSORBENCY, LUNG-FUNCTION, NO2, AREAS",
author = "Anna Moelter and Angela Simpson and Dietrich Berdel and Bert Brunekreef and Adnan Custovic and Josef Cyrys and {de Jongste}, Johan and {de Vocht}, Frank and Elaine Fuertes and Ulrike Gehring and Olena Gruzieva and Joachim Heinrich and Gerard Hoek and Barbara Hoffmann and Claudia Kluemper and Michal Korek and Kuhlbusch, {Thomas A. J.} and Sarah Lindley and Dirkje Postma and Christina Tischer and Alet Wijga and Goran Pershagen and Raymond Agius",
year = "2015",
month = "3",
doi = "10.1183/09031936.00083614",
language = "English",
volume = "45",
pages = "610--624",
journal = "European Respiratory Journal",
issn = "0903-1936",
publisher = "EUROPEAN RESPIRATORY SOC JOURNALS LTD",
number = "3",

}

RIS

TY - JOUR

T1 - A multicentre study of air pollution exposure and childhood asthma prevalence

T2 - the ESCAPE project

AU - Moelter, Anna

AU - Simpson, Angela

AU - Berdel, Dietrich

AU - Brunekreef, Bert

AU - Custovic, Adnan

AU - Cyrys, Josef

AU - de Jongste, Johan

AU - de Vocht, Frank

AU - Fuertes, Elaine

AU - Gehring, Ulrike

AU - Gruzieva, Olena

AU - Heinrich, Joachim

AU - Hoek, Gerard

AU - Hoffmann, Barbara

AU - Kluemper, Claudia

AU - Korek, Michal

AU - Kuhlbusch, Thomas A. J.

AU - Lindley, Sarah

AU - Postma, Dirkje

AU - Tischer, Christina

AU - Wijga, Alet

AU - Pershagen, Goran

AU - Agius, Raymond

PY - 2015/3

Y1 - 2015/3

N2 - The aim of this study was to determine the effect of six traffic-related air pollution metrics (nitrogen dioxide, nitrogen oxides, particulate matter with an aerodynamic diameterLand-use regression models were developed for each study area and used to estimate outdoor air pollution exposure at the home address of each child. Information on asthma and current wheeze prevalence at the ages of 4-5 and 8-10 years was collected using validated questionnaires. Multiple logistic regression was used to analyse the association between pollutant exposure and asthma within each cohort. Random-effects meta-analyses were used to combine effect estimates from individual cohorts.The meta-analyses showed no significant association between asthma prevalence and air pollution exposure (e.g. adjusted OR (95%CI) for asthma at age 8-10 years and exposure at the birth address (n=10377): 1.10 (0.81-1.49) per 10 mu g.m(-3) nitrogen dioxide; 0.88 (0.63-1.24) per 10 mu g.m(-3) PM10; 1.23 (0.78-1.95) per 5 mu g.m(-3) PM2.5). This result was consistently found in initial crude models, adjusted models and further sensitivity analyses.This study found no significant association between air pollution exposure and childhood asthma prevalence in five European birth cohorts.

AB - The aim of this study was to determine the effect of six traffic-related air pollution metrics (nitrogen dioxide, nitrogen oxides, particulate matter with an aerodynamic diameterLand-use regression models were developed for each study area and used to estimate outdoor air pollution exposure at the home address of each child. Information on asthma and current wheeze prevalence at the ages of 4-5 and 8-10 years was collected using validated questionnaires. Multiple logistic regression was used to analyse the association between pollutant exposure and asthma within each cohort. Random-effects meta-analyses were used to combine effect estimates from individual cohorts.The meta-analyses showed no significant association between asthma prevalence and air pollution exposure (e.g. adjusted OR (95%CI) for asthma at age 8-10 years and exposure at the birth address (n=10377): 1.10 (0.81-1.49) per 10 mu g.m(-3) nitrogen dioxide; 0.88 (0.63-1.24) per 10 mu g.m(-3) PM10; 1.23 (0.78-1.95) per 5 mu g.m(-3) PM2.5). This result was consistently found in initial crude models, adjusted models and further sensitivity analyses.This study found no significant association between air pollution exposure and childhood asthma prevalence in five European birth cohorts.

KW - USE REGRESSION-MODELS

KW - CHILDRENS RESPIRATORY SYMPTOMS

KW - LONG-TERM EXPOSURE

KW - BIRTH COHORT

KW - NITROGEN-DIOXIDE

KW - PARTICULATE MATTER

KW - PM2.5 ABSORBENCY

KW - LUNG-FUNCTION

KW - NO2

KW - AREAS

U2 - 10.1183/09031936.00083614

DO - 10.1183/09031936.00083614

M3 - Article

VL - 45

SP - 610

EP - 624

JO - European Respiratory Journal

JF - European Respiratory Journal

SN - 0903-1936

IS - 3

ER -

ID: 20097975