Publication

A comparison of very old patients admitted to intensive care unit after acute versus elective surgery or intervention

VIP1 Study Grp, Jung, C., Wernly, B., Muessig, J. M., Kelm, M., Boumendil, A., Morandi, A., Andersen, F. H., Artigas, A., Bertolini, G., Cecconi, M., Christensen, S., Faraldi, L., Fjolner, J., Lichtenauer, M., Bruno, R. R., Marsh, B., Moreno, R., Oeyen, S., Ohman, C. A., Pinto, B. B., Soliman, I. W., Szczeklik, W., Valentin, A., Watson, X., Zafeiridis, T., De Lange, D. W., Guidet, B. & Flaatten, H., Aug-2019, In : Journal of Critical Care. 52, p. 141-148 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

VIP1 Study Grp, Jung, C., Wernly, B., Muessig, J. M., Kelm, M., Boumendil, A., ... Flaatten, H. (2019). A comparison of very old patients admitted to intensive care unit after acute versus elective surgery or intervention. Journal of Critical Care, 52, 141-148. https://doi.org/10.1016/j.jcrc.2019.04.020

Author

VIP1 Study Grp ; Jung, Christian ; Wernly, Bernhard ; Muessig, Johanna M. ; Kelm, Malte ; Boumendil, Ariane ; Morandi, Alessandro ; Andersen, Finn H. ; Artigas, Antonio ; Bertolini, Guido ; Cecconi, Maurizio ; Christensen, Steffen ; Faraldi, Loredana ; Fjolner, Jesper ; Lichtenauer, Michael ; Bruno, Raphael Romano ; Marsh, Brian ; Moreno, Rui ; Oeyen, Sandra ; Ohman, Christina Agvald ; Pinto, Bernadro Bollen ; Soliman, Ivo W. ; Szczeklik, Wojciech ; Valentin, Andreas ; Watson, Ximena ; Zafeiridis, Tilemachos ; De Lange, Dylan W. ; Guidet, Bertrand ; Flaatten, Hans. / A comparison of very old patients admitted to intensive care unit after acute versus elective surgery or intervention. In: Journal of Critical Care. 2019 ; Vol. 52. pp. 141-148.

Harvard

VIP1 Study Grp, Jung, C, Wernly, B, Muessig, JM, Kelm, M, Boumendil, A, Morandi, A, Andersen, FH, Artigas, A, Bertolini, G, Cecconi, M, Christensen, S, Faraldi, L, Fjolner, J, Lichtenauer, M, Bruno, RR, Marsh, B, Moreno, R, Oeyen, S, Ohman, CA, Pinto, BB, Soliman, IW, Szczeklik, W, Valentin, A, Watson, X, Zafeiridis, T, De Lange, DW, Guidet, B & Flaatten, H 2019, 'A comparison of very old patients admitted to intensive care unit after acute versus elective surgery or intervention', Journal of Critical Care, vol. 52, pp. 141-148. https://doi.org/10.1016/j.jcrc.2019.04.020

Standard

A comparison of very old patients admitted to intensive care unit after acute versus elective surgery or intervention. / VIP1 Study Grp; Jung, Christian; Wernly, Bernhard; Muessig, Johanna M.; Kelm, Malte; Boumendil, Ariane; Morandi, Alessandro; Andersen, Finn H.; Artigas, Antonio; Bertolini, Guido; Cecconi, Maurizio; Christensen, Steffen; Faraldi, Loredana; Fjolner, Jesper; Lichtenauer, Michael; Bruno, Raphael Romano; Marsh, Brian; Moreno, Rui; Oeyen, Sandra; Ohman, Christina Agvald; Pinto, Bernadro Bollen; Soliman, Ivo W.; Szczeklik, Wojciech; Valentin, Andreas; Watson, Ximena; Zafeiridis, Tilemachos; De Lange, Dylan W.; Guidet, Bertrand; Flaatten, Hans.

In: Journal of Critical Care, Vol. 52, 08.2019, p. 141-148.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

VIP1 Study Grp, Jung C, Wernly B, Muessig JM, Kelm M, Boumendil A et al. A comparison of very old patients admitted to intensive care unit after acute versus elective surgery or intervention. Journal of Critical Care. 2019 Aug;52:141-148. https://doi.org/10.1016/j.jcrc.2019.04.020


BibTeX

@article{4896903c852c49f3a6f28f8eeafb9749,
title = "A comparison of very old patients admitted to intensive care unit after acute versus elective surgery or intervention",
abstract = "Background: We aimed to evaluate differences in outcome between patients admitted to intensive care unit (ICU) after elective versus acute surgery in a multinational cohort of very old patients (80 years; VIP). Predictors of mortality, with special emphasis on frailty, were assessed.Methods: In total, 5063 VIPs were induded in this analysis, 922 were admitted after elective surgery or intervention, 4141 acutely, with 402 after acute surgery. Differences were calculated using Mann-Whitney-U test and Wilcoxon test. Univariate and multivariable logistic regression were used to assess associations with mortality.Results: Compared patients admitted after acute surgery, patients admitted after elective surgery suffered less often from frailty as defined as CFS (28{\%} vs 46{\%}; p <0.001), evidenced lower SOFA scores (4 +/- 5 vs 7 +/- 7; p <0.001). Presence of frailty (CFS >4) was associated with significantly increased mortality both in elective surgery patients (7{\%} vs 12{\%}; p = 0.01), in acute surgery (7{\%} vs 12{\%}; p = 0.02).Conclusions: VIPs admitted to ICU after elective surgery evidenced favorable outcome over patients after acute surgery even after correction for relevant confounders. Frailty might be used to guide clinicians in risk stratification in both patients admitted after elective and acute surgery. (C) 2019 Elsevier Inc. All rights reserved.",
keywords = "Critically ill, Frailty, Elective, Outcome, Older, Old, QUALITY-OF-LIFE, ELDERLY-PATIENTS, CRITICAL ILLNESS, FRAILTY, MORTALITY, SCORE, PREDICTION, OUTCOMES, ICU",
author = "{VIP1 Study Grp} and Christian Jung and Bernhard Wernly and Muessig, {Johanna M.} and Malte Kelm and Ariane Boumendil and Alessandro Morandi and Andersen, {Finn H.} and Antonio Artigas and Guido Bertolini and Maurizio Cecconi and Steffen Christensen and Loredana Faraldi and Jesper Fjolner and Michael Lichtenauer and Bruno, {Raphael Romano} and Brian Marsh and Rui Moreno and Sandra Oeyen and Ohman, {Christina Agvald} and Pinto, {Bernadro Bollen} and Soliman, {Ivo W.} and Wojciech Szczeklik and Andreas Valentin and Ximena Watson and Tilemachos Zafeiridis and {De Lange}, {Dylan W.} and Bertrand Guidet and Hans Flaatten and Rene Schmutz and Franz Wimmer and Philipp Eller and Michael Joannidis and {De Buysscher}, Pieter and {De Neve}, Nikolaas and Walter Swinnen and Paul Abraham and Leila Hergafi and Schefold, {Joerg C.} and Ewelina Biskup and Petr Piza and Ioannis Taliadoros and Nilanjan Dey and Christoffer Solling and Rasmussen, {Bodil Steen} and Xavier Forceville and Guillaume Besch and Herve Mentec and Philippe Michel and Cristina Petrisor and Willem Dieperink",
year = "2019",
month = "8",
doi = "10.1016/j.jcrc.2019.04.020",
language = "English",
volume = "52",
pages = "141--148",
journal = "Journal of Critical Care",
issn = "0883-9441",
publisher = "W B SAUNDERS CO-ELSEVIER INC",

}

RIS

TY - JOUR

T1 - A comparison of very old patients admitted to intensive care unit after acute versus elective surgery or intervention

AU - VIP1 Study Grp

AU - Jung, Christian

AU - Wernly, Bernhard

AU - Muessig, Johanna M.

AU - Kelm, Malte

AU - Boumendil, Ariane

AU - Morandi, Alessandro

AU - Andersen, Finn H.

AU - Artigas, Antonio

AU - Bertolini, Guido

AU - Cecconi, Maurizio

AU - Christensen, Steffen

AU - Faraldi, Loredana

AU - Fjolner, Jesper

AU - Lichtenauer, Michael

AU - Bruno, Raphael Romano

AU - Marsh, Brian

AU - Moreno, Rui

AU - Oeyen, Sandra

AU - Ohman, Christina Agvald

AU - Pinto, Bernadro Bollen

AU - Soliman, Ivo W.

AU - Szczeklik, Wojciech

AU - Valentin, Andreas

AU - Watson, Ximena

AU - Zafeiridis, Tilemachos

AU - De Lange, Dylan W.

AU - Guidet, Bertrand

AU - Flaatten, Hans

AU - Schmutz, Rene

AU - Wimmer, Franz

AU - Eller, Philipp

AU - Joannidis, Michael

AU - De Buysscher, Pieter

AU - De Neve, Nikolaas

AU - Swinnen, Walter

AU - Abraham, Paul

AU - Hergafi, Leila

AU - Schefold, Joerg C.

AU - Biskup, Ewelina

AU - Piza, Petr

AU - Taliadoros, Ioannis

AU - Dey, Nilanjan

AU - Solling, Christoffer

AU - Rasmussen, Bodil Steen

AU - Forceville, Xavier

AU - Besch, Guillaume

AU - Mentec, Herve

AU - Michel, Philippe

AU - Petrisor, Cristina

AU - Dieperink, Willem

PY - 2019/8

Y1 - 2019/8

N2 - Background: We aimed to evaluate differences in outcome between patients admitted to intensive care unit (ICU) after elective versus acute surgery in a multinational cohort of very old patients (80 years; VIP). Predictors of mortality, with special emphasis on frailty, were assessed.Methods: In total, 5063 VIPs were induded in this analysis, 922 were admitted after elective surgery or intervention, 4141 acutely, with 402 after acute surgery. Differences were calculated using Mann-Whitney-U test and Wilcoxon test. Univariate and multivariable logistic regression were used to assess associations with mortality.Results: Compared patients admitted after acute surgery, patients admitted after elective surgery suffered less often from frailty as defined as CFS (28% vs 46%; p <0.001), evidenced lower SOFA scores (4 +/- 5 vs 7 +/- 7; p <0.001). Presence of frailty (CFS >4) was associated with significantly increased mortality both in elective surgery patients (7% vs 12%; p = 0.01), in acute surgery (7% vs 12%; p = 0.02).Conclusions: VIPs admitted to ICU after elective surgery evidenced favorable outcome over patients after acute surgery even after correction for relevant confounders. Frailty might be used to guide clinicians in risk stratification in both patients admitted after elective and acute surgery. (C) 2019 Elsevier Inc. All rights reserved.

AB - Background: We aimed to evaluate differences in outcome between patients admitted to intensive care unit (ICU) after elective versus acute surgery in a multinational cohort of very old patients (80 years; VIP). Predictors of mortality, with special emphasis on frailty, were assessed.Methods: In total, 5063 VIPs were induded in this analysis, 922 were admitted after elective surgery or intervention, 4141 acutely, with 402 after acute surgery. Differences were calculated using Mann-Whitney-U test and Wilcoxon test. Univariate and multivariable logistic regression were used to assess associations with mortality.Results: Compared patients admitted after acute surgery, patients admitted after elective surgery suffered less often from frailty as defined as CFS (28% vs 46%; p <0.001), evidenced lower SOFA scores (4 +/- 5 vs 7 +/- 7; p <0.001). Presence of frailty (CFS >4) was associated with significantly increased mortality both in elective surgery patients (7% vs 12%; p = 0.01), in acute surgery (7% vs 12%; p = 0.02).Conclusions: VIPs admitted to ICU after elective surgery evidenced favorable outcome over patients after acute surgery even after correction for relevant confounders. Frailty might be used to guide clinicians in risk stratification in both patients admitted after elective and acute surgery. (C) 2019 Elsevier Inc. All rights reserved.

KW - Critically ill

KW - Frailty

KW - Elective

KW - Outcome

KW - Older

KW - Old

KW - QUALITY-OF-LIFE

KW - ELDERLY-PATIENTS

KW - CRITICAL ILLNESS

KW - FRAILTY

KW - MORTALITY

KW - SCORE

KW - PREDICTION

KW - OUTCOMES

KW - ICU

U2 - 10.1016/j.jcrc.2019.04.020

DO - 10.1016/j.jcrc.2019.04.020

M3 - Article

VL - 52

SP - 141

EP - 148

JO - Journal of Critical Care

JF - Journal of Critical Care

SN - 0883-9441

ER -

ID: 88337228