Publication

A cluster-randomized controlled trial to study the effectiveness of a protocol-based lifestyle program to prevent type 2 diabetes in people with impaired fasting glucose

Hesselink, A. E., Bilo, H. J. G., Jonkers, R., Martens, M., de Weerdt, I. & Rutten, G. E. H., 2-Dec-2013, In : BMC Family Practice. 14, 7 p., 184.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Hesselink, A. E., Bilo, H. J. G., Jonkers, R., Martens, M., de Weerdt, I., & Rutten, G. E. H. (2013). A cluster-randomized controlled trial to study the effectiveness of a protocol-based lifestyle program to prevent type 2 diabetes in people with impaired fasting glucose. BMC Family Practice, 14, [184]. https://doi.org/10.1186/1471-2296-14-184

Author

Hesselink, Arlette E. ; Bilo, Henk J. G. ; Jonkers, Ruud ; Martens, Marloes ; de Weerdt, Inge ; Rutten, Guy E. H. / A cluster-randomized controlled trial to study the effectiveness of a protocol-based lifestyle program to prevent type 2 diabetes in people with impaired fasting glucose. In: BMC Family Practice. 2013 ; Vol. 14.

Harvard

Hesselink, AE, Bilo, HJG, Jonkers, R, Martens, M, de Weerdt, I & Rutten, GEH 2013, 'A cluster-randomized controlled trial to study the effectiveness of a protocol-based lifestyle program to prevent type 2 diabetes in people with impaired fasting glucose', BMC Family Practice, vol. 14, 184. https://doi.org/10.1186/1471-2296-14-184

Standard

A cluster-randomized controlled trial to study the effectiveness of a protocol-based lifestyle program to prevent type 2 diabetes in people with impaired fasting glucose. / Hesselink, Arlette E.; Bilo, Henk J. G.; Jonkers, Ruud; Martens, Marloes; de Weerdt, Inge; Rutten, Guy E. H.

In: BMC Family Practice, Vol. 14, 184, 02.12.2013.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Hesselink AE, Bilo HJG, Jonkers R, Martens M, de Weerdt I, Rutten GEH. A cluster-randomized controlled trial to study the effectiveness of a protocol-based lifestyle program to prevent type 2 diabetes in people with impaired fasting glucose. BMC Family Practice. 2013 Dec 2;14. 184. https://doi.org/10.1186/1471-2296-14-184


BibTeX

@article{45c030151e8d4e03bb2a9e9e3c96f104,
title = "A cluster-randomized controlled trial to study the effectiveness of a protocol-based lifestyle program to prevent type 2 diabetes in people with impaired fasting glucose",
abstract = "Background: Effective diabetes prevention strategies that can be implemented in daily practice, without huge amounts of money and a lot of personnel are needed. The Dutch Diabetes Federation developed a protocol for coaching people with impaired fasting glucose (IFG; according to WHO criteria: 6.1 to 6.9 mmol/l) to a sustainable healthy lifestyle change: 'the road map towards diabetes prevention' (abbreviated: Road Map: RM). This protocol is applied within a primary health care setting by a general practitioner and a practice nurse. The feasibility and (cost-) effectiveness of care provided according to the RM protocol will be evaluated.Methods/Design: A cluster randomised clinical trial is performed, with randomisation at the level of the general practices. Both opportunistic screening and active case finding took place among clients with high risk factors for diabetes. After IFG is diagnosed, motivated people in the intervention practices receive 3-4 consultations by the practice nurse within one year. During these consultations they are coached to increase the level of physical activity and healthy dietary habits. If necessary, participants are referred to a dietician, physiotherapist, lifestyle programs and/or local sports activities. The control group receives care as usual. The primary outcome measure in this study is change in Body Mass Index (BMI). Secondary outcome measures are waist circumference, physical activity, total and saturated fat intake, systolic blood pressure, blood glucose, total cholesterol, HDL cholesterol, triglycerides and behaviour determinants like risk perception, perceived knowledge and motivation. Based on a sample size calculation 120 people in each group are needed. Measurements are performed at baseline, and after one (post-intervention) and two years follow up. Anthropometrics and biochemical parameters are assessed in the practices and physical activity, food intake and their determinants by a validated questionnaire. The cost-effectiveness is estimated by using the Chronic Disease Model (CDM). Feasibility will be tested by interviews among health care professionals.Discussion: The results of the study will provide valuable information for both health care professionals and policy makers. If this study shows the RM to be both effective and cost-effective the protocol can be implemented on a large scale.",
keywords = "Diabetes, Prevention, Healthy life style intervention, Impaired fasting glucose, Primary care health services, Randomized clinical trial, RELATIVE VALIDITY, FOLLOW-UP, TOLERANCE, QUESTIONNAIRE, INTERVENTION, RISK",
author = "Hesselink, {Arlette E.} and Bilo, {Henk J. G.} and Ruud Jonkers and Marloes Martens and {de Weerdt}, Inge and Rutten, {Guy E. H.}",
note = "Trial registration: ISRCTN41209683. Ethical approval number: NL31342.075.10.",
year = "2013",
month = "12",
day = "2",
doi = "10.1186/1471-2296-14-184",
language = "English",
volume = "14",
journal = "BMC Family Practice",
issn = "1471-2296",
publisher = "BioMed Central Ltd.",

}

RIS

TY - JOUR

T1 - A cluster-randomized controlled trial to study the effectiveness of a protocol-based lifestyle program to prevent type 2 diabetes in people with impaired fasting glucose

AU - Hesselink, Arlette E.

AU - Bilo, Henk J. G.

AU - Jonkers, Ruud

AU - Martens, Marloes

AU - de Weerdt, Inge

AU - Rutten, Guy E. H.

N1 - Trial registration: ISRCTN41209683. Ethical approval number: NL31342.075.10.

PY - 2013/12/2

Y1 - 2013/12/2

N2 - Background: Effective diabetes prevention strategies that can be implemented in daily practice, without huge amounts of money and a lot of personnel are needed. The Dutch Diabetes Federation developed a protocol for coaching people with impaired fasting glucose (IFG; according to WHO criteria: 6.1 to 6.9 mmol/l) to a sustainable healthy lifestyle change: 'the road map towards diabetes prevention' (abbreviated: Road Map: RM). This protocol is applied within a primary health care setting by a general practitioner and a practice nurse. The feasibility and (cost-) effectiveness of care provided according to the RM protocol will be evaluated.Methods/Design: A cluster randomised clinical trial is performed, with randomisation at the level of the general practices. Both opportunistic screening and active case finding took place among clients with high risk factors for diabetes. After IFG is diagnosed, motivated people in the intervention practices receive 3-4 consultations by the practice nurse within one year. During these consultations they are coached to increase the level of physical activity and healthy dietary habits. If necessary, participants are referred to a dietician, physiotherapist, lifestyle programs and/or local sports activities. The control group receives care as usual. The primary outcome measure in this study is change in Body Mass Index (BMI). Secondary outcome measures are waist circumference, physical activity, total and saturated fat intake, systolic blood pressure, blood glucose, total cholesterol, HDL cholesterol, triglycerides and behaviour determinants like risk perception, perceived knowledge and motivation. Based on a sample size calculation 120 people in each group are needed. Measurements are performed at baseline, and after one (post-intervention) and two years follow up. Anthropometrics and biochemical parameters are assessed in the practices and physical activity, food intake and their determinants by a validated questionnaire. The cost-effectiveness is estimated by using the Chronic Disease Model (CDM). Feasibility will be tested by interviews among health care professionals.Discussion: The results of the study will provide valuable information for both health care professionals and policy makers. If this study shows the RM to be both effective and cost-effective the protocol can be implemented on a large scale.

AB - Background: Effective diabetes prevention strategies that can be implemented in daily practice, without huge amounts of money and a lot of personnel are needed. The Dutch Diabetes Federation developed a protocol for coaching people with impaired fasting glucose (IFG; according to WHO criteria: 6.1 to 6.9 mmol/l) to a sustainable healthy lifestyle change: 'the road map towards diabetes prevention' (abbreviated: Road Map: RM). This protocol is applied within a primary health care setting by a general practitioner and a practice nurse. The feasibility and (cost-) effectiveness of care provided according to the RM protocol will be evaluated.Methods/Design: A cluster randomised clinical trial is performed, with randomisation at the level of the general practices. Both opportunistic screening and active case finding took place among clients with high risk factors for diabetes. After IFG is diagnosed, motivated people in the intervention practices receive 3-4 consultations by the practice nurse within one year. During these consultations they are coached to increase the level of physical activity and healthy dietary habits. If necessary, participants are referred to a dietician, physiotherapist, lifestyle programs and/or local sports activities. The control group receives care as usual. The primary outcome measure in this study is change in Body Mass Index (BMI). Secondary outcome measures are waist circumference, physical activity, total and saturated fat intake, systolic blood pressure, blood glucose, total cholesterol, HDL cholesterol, triglycerides and behaviour determinants like risk perception, perceived knowledge and motivation. Based on a sample size calculation 120 people in each group are needed. Measurements are performed at baseline, and after one (post-intervention) and two years follow up. Anthropometrics and biochemical parameters are assessed in the practices and physical activity, food intake and their determinants by a validated questionnaire. The cost-effectiveness is estimated by using the Chronic Disease Model (CDM). Feasibility will be tested by interviews among health care professionals.Discussion: The results of the study will provide valuable information for both health care professionals and policy makers. If this study shows the RM to be both effective and cost-effective the protocol can be implemented on a large scale.

KW - Diabetes

KW - Prevention

KW - Healthy life style intervention

KW - Impaired fasting glucose

KW - Primary care health services

KW - Randomized clinical trial

KW - RELATIVE VALIDITY

KW - FOLLOW-UP

KW - TOLERANCE

KW - QUESTIONNAIRE

KW - INTERVENTION

KW - RISK

U2 - 10.1186/1471-2296-14-184

DO - 10.1186/1471-2296-14-184

M3 - Article

VL - 14

JO - BMC Family Practice

JF - BMC Family Practice

SN - 1471-2296

M1 - 184

ER -

ID: 6008706