Publication

A brief period of sleep deprivation leads to subtle changes in mouse gut microbiota

El Aidy, S., Bolsius, Y. G., Raven, F. & Havekes, R., 12-Sep-2019, In : Journal of Sleep Research. 8 p., e12920.

Research output: Contribution to journalArticleAcademicpeer-review

APA

El Aidy, S., Bolsius, Y. G., Raven, F., & Havekes, R. (2019). A brief period of sleep deprivation leads to subtle changes in mouse gut microbiota. Journal of Sleep Research, [e12920]. https://doi.org/10.1111/jsr.12920

Author

El Aidy, Sahar ; Bolsius, Youri G. ; Raven, Frank ; Havekes, Robbert. / A brief period of sleep deprivation leads to subtle changes in mouse gut microbiota. In: Journal of Sleep Research. 2019.

Harvard

El Aidy, S, Bolsius, YG, Raven, F & Havekes, R 2019, 'A brief period of sleep deprivation leads to subtle changes in mouse gut microbiota', Journal of Sleep Research. https://doi.org/10.1111/jsr.12920

Standard

A brief period of sleep deprivation leads to subtle changes in mouse gut microbiota. / El Aidy, Sahar; Bolsius, Youri G.; Raven, Frank; Havekes, Robbert.

In: Journal of Sleep Research, 12.09.2019.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

El Aidy S, Bolsius YG, Raven F, Havekes R. A brief period of sleep deprivation leads to subtle changes in mouse gut microbiota. Journal of Sleep Research. 2019 Sep 12. e12920. https://doi.org/10.1111/jsr.12920


BibTeX

@article{cb9d4f90c28e45ddbb9e3883074b8d43,
title = "A brief period of sleep deprivation leads to subtle changes in mouse gut microbiota",
abstract = "Not getting enough sleep is a common problem in our society and contributes to numerous health problems, including high blood pressure, diabetes and obesity. Related to these observations, a wealth of studies has underscored the negative impact of both acute and chronic sleep deprivation on cognitive function. More recently it has become apparent that the gut microbiota composition can be rapidly altered, modulates brain function and is affected by the aforementioned health problems. As such, changes in the microbiota composition may contribute to the behavioural and physiological phenotypes associated with sleep deprivation. It is unclear, however, whether a brief period of sleep deprivation can also negatively impact the gut microbiota. Here, we examined the impact of 5 hr of sleep deprivation on gut microbiota composition of male C57Bl6/J mice. Despite the fact that the overall microbial composition did not change between the control- and sleep-deprived groups, the relative abundance of the Clostridiaceae and Lachnospiraceae were slightly altered in sleep-deprived animals compared to controls. Together, these data suggest that depriving mice of sleep for 5 hr leads to subtle changes in the gut microbiota composition.",
keywords = "gut, mice, microbiome, microbiota, sleep, sleep deprivation",
author = "{El Aidy}, Sahar and Bolsius, {Youri G.} and Frank Raven and Robbert Havekes",
note = "{\circledC} 2019 The Authors. Journal of Sleep Research published by John Wiley & Sons Ltd on behalf of European Sleep Research Society.",
year = "2019",
month = "9",
day = "12",
doi = "10.1111/jsr.12920",
language = "English",
journal = "Journal of Sleep Research",
issn = "0962-1105",
publisher = "Wiley",

}

RIS

TY - JOUR

T1 - A brief period of sleep deprivation leads to subtle changes in mouse gut microbiota

AU - El Aidy, Sahar

AU - Bolsius, Youri G.

AU - Raven, Frank

AU - Havekes, Robbert

N1 - © 2019 The Authors. Journal of Sleep Research published by John Wiley & Sons Ltd on behalf of European Sleep Research Society.

PY - 2019/9/12

Y1 - 2019/9/12

N2 - Not getting enough sleep is a common problem in our society and contributes to numerous health problems, including high blood pressure, diabetes and obesity. Related to these observations, a wealth of studies has underscored the negative impact of both acute and chronic sleep deprivation on cognitive function. More recently it has become apparent that the gut microbiota composition can be rapidly altered, modulates brain function and is affected by the aforementioned health problems. As such, changes in the microbiota composition may contribute to the behavioural and physiological phenotypes associated with sleep deprivation. It is unclear, however, whether a brief period of sleep deprivation can also negatively impact the gut microbiota. Here, we examined the impact of 5 hr of sleep deprivation on gut microbiota composition of male C57Bl6/J mice. Despite the fact that the overall microbial composition did not change between the control- and sleep-deprived groups, the relative abundance of the Clostridiaceae and Lachnospiraceae were slightly altered in sleep-deprived animals compared to controls. Together, these data suggest that depriving mice of sleep for 5 hr leads to subtle changes in the gut microbiota composition.

AB - Not getting enough sleep is a common problem in our society and contributes to numerous health problems, including high blood pressure, diabetes and obesity. Related to these observations, a wealth of studies has underscored the negative impact of both acute and chronic sleep deprivation on cognitive function. More recently it has become apparent that the gut microbiota composition can be rapidly altered, modulates brain function and is affected by the aforementioned health problems. As such, changes in the microbiota composition may contribute to the behavioural and physiological phenotypes associated with sleep deprivation. It is unclear, however, whether a brief period of sleep deprivation can also negatively impact the gut microbiota. Here, we examined the impact of 5 hr of sleep deprivation on gut microbiota composition of male C57Bl6/J mice. Despite the fact that the overall microbial composition did not change between the control- and sleep-deprived groups, the relative abundance of the Clostridiaceae and Lachnospiraceae were slightly altered in sleep-deprived animals compared to controls. Together, these data suggest that depriving mice of sleep for 5 hr leads to subtle changes in the gut microbiota composition.

KW - gut

KW - mice

KW - microbiome

KW - microbiota

KW - sleep

KW - sleep deprivation

U2 - 10.1111/jsr.12920

DO - 10.1111/jsr.12920

M3 - Article

JO - Journal of Sleep Research

JF - Journal of Sleep Research

SN - 0962-1105

M1 - e12920

ER -

ID: 97119726