Publication

{[1,4-DHPyrazine][C(CN)(3)](2)} as a New Nano Molten Salt Catalyst for the Synthesis of Novel Piperazine Based bis(4-hydroxy-2H-chromen-2-one) Derivatives

Baghery, S., Zolfigol, M. A., Schirhagl, R. & Hasani, M., Aug-2017, In : Catalysis Letters. 147, 8, p. 2083-2099 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Baghery, S., Zolfigol, M. A., Schirhagl, R., & Hasani, M. (2017). {[1,4-DHPyrazine][C(CN)(3)](2)} as a New Nano Molten Salt Catalyst for the Synthesis of Novel Piperazine Based bis(4-hydroxy-2H-chromen-2-one) Derivatives. Catalysis Letters, 147(8), 2083-2099. https://doi.org/10.1007/s10562-017-2096-3

Author

Baghery, Saeed ; Zolfigol, Mohammad Ali ; Schirhagl, Romana ; Hasani, Masoumeh. / {[1,4-DHPyrazine][C(CN)(3)](2)} as a New Nano Molten Salt Catalyst for the Synthesis of Novel Piperazine Based bis(4-hydroxy-2H-chromen-2-one) Derivatives. In: Catalysis Letters. 2017 ; Vol. 147, No. 8. pp. 2083-2099.

Harvard

Baghery, S, Zolfigol, MA, Schirhagl, R & Hasani, M 2017, '{[1,4-DHPyrazine][C(CN)(3)](2)} as a New Nano Molten Salt Catalyst for the Synthesis of Novel Piperazine Based bis(4-hydroxy-2H-chromen-2-one) Derivatives', Catalysis Letters, vol. 147, no. 8, pp. 2083-2099. https://doi.org/10.1007/s10562-017-2096-3

Standard

{[1,4-DHPyrazine][C(CN)(3)](2)} as a New Nano Molten Salt Catalyst for the Synthesis of Novel Piperazine Based bis(4-hydroxy-2H-chromen-2-one) Derivatives. / Baghery, Saeed; Zolfigol, Mohammad Ali; Schirhagl, Romana; Hasani, Masoumeh.

In: Catalysis Letters, Vol. 147, No. 8, 08.2017, p. 2083-2099.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Baghery S, Zolfigol MA, Schirhagl R, Hasani M. {[1,4-DHPyrazine][C(CN)(3)](2)} as a New Nano Molten Salt Catalyst for the Synthesis of Novel Piperazine Based bis(4-hydroxy-2H-chromen-2-one) Derivatives. Catalysis Letters. 2017 Aug;147(8):2083-2099. https://doi.org/10.1007/s10562-017-2096-3


BibTeX

@article{1b94e1816e964f25a2965d28e16f5dd9,
title = "{[1,4-DHPyrazine][C(CN)(3)](2)} as a New Nano Molten Salt Catalyst for the Synthesis of Novel Piperazine Based bis(4-hydroxy-2H-chromen-2-one) Derivatives",
abstract = "In this article a convenient method for the synthesis of novel piperazine based bis(4-hydroxy-2H-chromen-2-one) derivatives using pyrazine-1,4-diium tricyanomethanide {[1,4-DHPyrazine][C(CN)(3)](2)} as a new nanostructured molten salt (NMS) catalyst has been described. These compounds were synthesized via Mannich type reaction between several aromatic aldehyde, piperazine and 4-hydroxycoumarin under solvent-free condition at room temperature. The NMS catalyst was fully characterized via Fourier transform infrared (FT-IR), nuclear magnetic resonance (H-1 NMR and C-13 NMR), mass spectrometry, thermal gravimetric, derivative thermal gravimetric, differential thermal analysis, X-ray diffraction patterns, scanning electron microscopy and transmission electron microscopy analysis. The new compounds synthesized by using this NMS catalyst were also characterized by FT-IR, H-1 NMR and C-13 NMR, high-resolution mass spectrometry techniques. The new NMS catalyst simply recovers and can be reused several times without significant loss of catalytic activity. The major advantages of the described method in comparison to the classical reactions are low catalyst loading, short reaction time, high yields, simple isolation of product and reusability of the NMS catalyst.Pyrazine-1,4-diium tricyanomethanide as a nano molten salt catalyst was designed, synthesized and used for the synthesis of novel biological piperazine based bis(4-hydroxy-2H-chromen-2- one) derivatives as bioactive and drug candidates.[GRAPHICS].",
keywords = "Pyrazine-1,4-diium tricyanomethanide {[1,4-DHPyrazine][C(CN)(3)](2)}, 3,3 '-(Piperazine-1,4-diylbis(arylmethylene))bis(4-hydroxy-2H-chromen-2-one), Nanostructured molten salt (NMS), ANOMERIC BASED OXIDATION, IN-SITU GENERATION, ACID IONIC LIQUID, AQUEOUS-MEDIA, AROMATIC-COMPOUNDS, NITRATION, DESIGN, NANOPARTICLES, ANTICANCER, SOLVENTS",
author = "Saeed Baghery and Zolfigol, {Mohammad Ali} and Romana Schirhagl and Masoumeh Hasani",
year = "2017",
month = "8",
doi = "10.1007/s10562-017-2096-3",
language = "English",
volume = "147",
pages = "2083--2099",
journal = "Catalysis Letters",
issn = "1011-372X",
publisher = "SPRINGER",
number = "8",

}

RIS

TY - JOUR

T1 - {[1,4-DHPyrazine][C(CN)(3)](2)} as a New Nano Molten Salt Catalyst for the Synthesis of Novel Piperazine Based bis(4-hydroxy-2H-chromen-2-one) Derivatives

AU - Baghery, Saeed

AU - Zolfigol, Mohammad Ali

AU - Schirhagl, Romana

AU - Hasani, Masoumeh

PY - 2017/8

Y1 - 2017/8

N2 - In this article a convenient method for the synthesis of novel piperazine based bis(4-hydroxy-2H-chromen-2-one) derivatives using pyrazine-1,4-diium tricyanomethanide {[1,4-DHPyrazine][C(CN)(3)](2)} as a new nanostructured molten salt (NMS) catalyst has been described. These compounds were synthesized via Mannich type reaction between several aromatic aldehyde, piperazine and 4-hydroxycoumarin under solvent-free condition at room temperature. The NMS catalyst was fully characterized via Fourier transform infrared (FT-IR), nuclear magnetic resonance (H-1 NMR and C-13 NMR), mass spectrometry, thermal gravimetric, derivative thermal gravimetric, differential thermal analysis, X-ray diffraction patterns, scanning electron microscopy and transmission electron microscopy analysis. The new compounds synthesized by using this NMS catalyst were also characterized by FT-IR, H-1 NMR and C-13 NMR, high-resolution mass spectrometry techniques. The new NMS catalyst simply recovers and can be reused several times without significant loss of catalytic activity. The major advantages of the described method in comparison to the classical reactions are low catalyst loading, short reaction time, high yields, simple isolation of product and reusability of the NMS catalyst.Pyrazine-1,4-diium tricyanomethanide as a nano molten salt catalyst was designed, synthesized and used for the synthesis of novel biological piperazine based bis(4-hydroxy-2H-chromen-2- one) derivatives as bioactive and drug candidates.[GRAPHICS].

AB - In this article a convenient method for the synthesis of novel piperazine based bis(4-hydroxy-2H-chromen-2-one) derivatives using pyrazine-1,4-diium tricyanomethanide {[1,4-DHPyrazine][C(CN)(3)](2)} as a new nanostructured molten salt (NMS) catalyst has been described. These compounds were synthesized via Mannich type reaction between several aromatic aldehyde, piperazine and 4-hydroxycoumarin under solvent-free condition at room temperature. The NMS catalyst was fully characterized via Fourier transform infrared (FT-IR), nuclear magnetic resonance (H-1 NMR and C-13 NMR), mass spectrometry, thermal gravimetric, derivative thermal gravimetric, differential thermal analysis, X-ray diffraction patterns, scanning electron microscopy and transmission electron microscopy analysis. The new compounds synthesized by using this NMS catalyst were also characterized by FT-IR, H-1 NMR and C-13 NMR, high-resolution mass spectrometry techniques. The new NMS catalyst simply recovers and can be reused several times without significant loss of catalytic activity. The major advantages of the described method in comparison to the classical reactions are low catalyst loading, short reaction time, high yields, simple isolation of product and reusability of the NMS catalyst.Pyrazine-1,4-diium tricyanomethanide as a nano molten salt catalyst was designed, synthesized and used for the synthesis of novel biological piperazine based bis(4-hydroxy-2H-chromen-2- one) derivatives as bioactive and drug candidates.[GRAPHICS].

KW - Pyrazine-1,4-diium tricyanomethanide {[1,4-DHPyrazine][C(CN)(3)](2)}

KW - 3,3 '-(Piperazine-1,4-diylbis(arylmethylene))bis(4-hydroxy-2H-chromen-2-one)

KW - Nanostructured molten salt (NMS)

KW - ANOMERIC BASED OXIDATION

KW - IN-SITU GENERATION

KW - ACID IONIC LIQUID

KW - AQUEOUS-MEDIA

KW - AROMATIC-COMPOUNDS

KW - NITRATION

KW - DESIGN

KW - NANOPARTICLES

KW - ANTICANCER

KW - SOLVENTS

U2 - 10.1007/s10562-017-2096-3

DO - 10.1007/s10562-017-2096-3

M3 - Article

VL - 147

SP - 2083

EP - 2099

JO - Catalysis Letters

JF - Catalysis Letters

SN - 1011-372X

IS - 8

ER -

ID: 46993850