Social factors in cognitive decline and dementia: Towards an early intervention approach
Kas, M. & Lanooij, S.
01/03/2018 → 01/03/2022
Studies in mice allow for in depth brain health analyses of neuroinflammatory and neurogenesis markers. This will be studied in socially isolated versus group housed mice, in two validated genetic mouse models for dementia. These two different models (an amyloid model and a tau model) each represent critical components of Alzheimer’s disease putatively with their own impact on social behaviour and sensitivity to the development of neuro-inflammation, loss of synaptic plasticity and sensitivity to interventions. Secondly, we will examine whether differences in physical activity levels contribute to social health and cognitive functioning, to potentially prevent and/or reduce the development of dementia.
|Effective start/end date||01/03/2018 → 01/03/2022|
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Press/Media: Research › Academic