W.J. Kolff Institute for Biomedical Engineering and Materials Science (KOLFF)

University of Groningen > Faculteit Medische Wetenschappen/UMCG > W.J. Kolff Institute for Biomedical Engineering and Materials Science (KOLFF)

Contact information

Antonius Deusinglaan 1, FB41
9713 AV
  • Phone: +31 50 3633140

Organisational unit profile

The W.J. Kolff Institute for Biomedical Engineering and Materials Science was established on October 8th, 1997. The institute is named after Willem Johan Kolff, who as a resident in Groningen, developed the first functioning artificial kidney in the 1940th and saved lives of millions of patients ever since.

The use of biomaterials implants has become an integral part of modern health care in the Western world. Modern health care could not even exist without biomaterials and the restoration of function after oncological surgery, trauma or simply wear due to advanced age would be impossible. With the average life expectancy approaching 80 years, the use of biomaterials will increase due to the demands of the ageing population for a high quality of life.

The mission statement of the W.J. Kolff Institute is to establish a center of expertise for the entire stage of biomedical materials science and its application involving basic materials science, medical product development and clinical evaluation that will contribute to the long-lasting well-being of patients in need of biomaterials implants and extra-corporal support systems.

Research Focus and Strategy

  • Bioadhesion, biocompatibility and infection: Focusses on the prevention of biofilm formation on all biomaterials implants and devices, its aims are formulated with respect to the infection prevention of temporarily and permanent implants and devices.
  • Nanobiotechnology and advanced therapeutic materials: Employs tools from nanobiotechnology to fabricate powerful drug carrier systems and nanoscale surface coatings.
  • Restoring organ function by means of regenerative medicine: Focuses on various aspects of tissue (re) generation, repair and remodelling, including inflammation.
  • Maintaining oral health and oral function: Provides new tools for prevention of oral health disorders to occur and to produce new strategies to restore and maintain oral health and function during life with minimal costs and efforts.


Scientific Director


Prof. dr. H.C. van der Mei
E-mail: h.c.van.der.mei@umcg.nl
Phone: +31 50 3633140
Fax: +31 50 3633159


  1. PET and SPECT in Brain AVMs and Cerebral Proliferative Angiopathy

    van Dijk, J. M. C., Krings, T., Doorduin, J. & Slart, R., 2020, PET and SPECT in Neurology - Second Edition. Dierckx, R., Otte, A., de Vries, E. & van Waarde, A. (eds.). 2 ed. Springer, p. 629 650 p.

    Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

  2. Regulation of cellular senescence by extracellular matrix during chronic fibrotic diseases

    Blokland, K. E. C., Pouwels, S. D., Schuliga, M., Knight, D. A. & Burgess, J. K., 2020, In : Clinical Science. 134, 20, p. 2681-2706 26 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. Reducing the Carbon Footprint of Academic Conferences: The Example of the American Society of Tropical Medicine and Hygiene

    Bousema, T., Selvaraj, P., Djimde, A. A., Yakar, D., Hagedorn, B., Pratt, A., Barret, D., Whitfield, K. & Cohen, J. M., 2020, In : American Journal of Tropical Medicine and Hygiene.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Towards a benchmark of abdominal CT use during duty shifts: 15-year sample from the Netherlands

    Mengou, I. V., Yakar, D., Kasalak, Ö. & Kwee, T. C., 2020, In : Abdominal radiology (New York).

    Research output: Contribution to journalArticleAcademicpeer-review

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  1. Dataset: Ovalbumin-containing core-shell implants suitable to obtain a delayed IgG1 antibody response in support of a biphasic pulsatile release profile in mice

    Amssoms, K. (Creator), Born, P. (Creator), Beugeling, M. (Creator), De Clerck, B. (Creator), Van Gulck, E. (Creator), Hinrichs, W. (Creator), Frijlink, E. (Creator), Grasmeijer, N. (Creator), Kraus, G. (Creator), Sutmuller, R. (Creator), Simmen, K. (Creator), Baert, L. (Creator), University of Groningen, 17-Aug-2018


  2. Data for: ColiCoords: A Python package for the analysis of bacterial fluorescence microscopy data

    Smit, J. (Creator), Li, Y. (Creator), Warszawik, E. (Creator), Hermann, A. (Creator), Cordes, T. (Creator), University of Groningen, 12-Apr-2019


  3. Data from: Sialendoscopy enhances salivary gland function in Sjögren’s syndrome: a 6 month follow-up, randomized and controlled, single blind study

    Karagozoglu, K. H. (Creator), Vissink, A. (Creator), Forouzanfar, T. (Creator), Brand, H. S. (Creator), Maarse, F. (Creator), Jager, D. (Creator), University of Groningen, 28-Feb-2018


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  1. ZonMW-VIDI Committee

    Marianne Rots (Recipient), 2020

    Prize: AppointmentAcademic

  2. Management Committee International Nucleome Consortium

    Marianne Rots (Recipient), 2020

    Prize: National/international honourAcademic

  3. Editor in Chief Epigenetics Communication

    Marianne Rots (Recipient), 8-Oct-2020

    Prize: AppointmentAcademic

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  1. American Thoracic Society (ATS) (External organisation)

    Janette Burgess (Member)

    Activity: MembershipMembership of committeeProfessional

  2. Jose Manuel Rodrigo Muñoz

    Marianne Rots (Host)

    Activity: Hosting a visitorAcademic

  3. Epigenetic editing: contexts matter

    Marianne Rots (Speaker)

    Activity: Talk or presentationAcademic

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Press / Media
  1. Moleculaire processen zichtbaar maken met PET

    Erik Vries, de


    1 Media contribution

    Press/Media: ResearchProfessional

  2. Zorgen over opstarten orthopedische zorg de achterstand halen we niet snel in

    Sjoerd Bulstra


    1 Media contribution

    Press/Media: Public Engagement ActivitiesPopular

  3. Artsen bezorgd over gebruik urgentielijst als triagemiddel.

    Sjoerd Bulstra


    1 Media contribution

    Press/Media: Expert CommentAcademic

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