W.J. Kolff Institute for Biomedical Engineering and Materials Science

University of Groningen > Faculty of Medical Sciences > W.J. Kolff Institute for Biomedical Engineering and Materials Science

Contact information

Antonius Deusinglaan 1, FB41
9713 AV
  • Phone: +31 50 3633140

Organisational unit profile

The W.J. Kolff Institute for Biomedical Engineering and Materials Science was established on October 8th, 1997. The institute is named after Willem Johan Kolff, who as a resident in Groningen, developed the first functioning artificial kidney in the 1940th and saved lives of millions of patients ever since.

The use of biomaterials implants has become an integral part of modern health care in the Western world. Modern health care could not even exist without biomaterials and the restoration of function after oncological surgery, trauma or simply wear due to advanced age would be impossible. With the average life expectancy approaching 80 years, the use of biomaterials will increase due to the demands of the ageing population for a high quality of life.

The mission statement of the W.J. Kolff Institute is to establish a center of expertise for the entire stage of biomedical materials science and its application involving basic materials science, medical product development and clinical evaluation that will contribute to the long-lasting well-being of patients in need of biomaterials implants and extra-corporal support systems.

Research Focus and Strategy

  • Bioadhesion, biocompatibility and infection: Focusses on the prevention of biofilm formation on all biomaterials implants and devices, its aims are formulated with respect to the infection prevention of temporarily and permanent implants and devices.
  • Nanobiotechnology and advanced therapeutic materials: Employs tools from nanobiotechnology to fabricate powerful drug carrier systems and nanoscale surface coatings.
  • Restoring organ function by means of regenerative medicine: Focuses on various aspects of tissue (re) generation, repair and remodelling, including inflammation.
  • Maintaining oral health and oral function: Provides new tools for prevention of oral health disorders to occur and to produce new strategies to restore and maintain oral health and function during life with minimal costs and efforts.


Scientific Director


Prof. dr. H.C. van der Mei
E-mail: h.c.van.der.mei@umcg.nl
Phone: +31 50 3633140
Fax: +31 50 3633159


  1. In vitro methods for the evaluation of antimicrobial surface designs

    Sjollema, J., Zaat, S. A. J., Fontaine, V., Ramstedt, M., Luginbuehl, R., Thevissen, K., Li, J., van der Mei, H. C. & Busscher, H. J. 9-Feb-2018 In : Acta Biomaterialia.

    Research output: Scientific - peer-reviewReview article

  2. Mesenchymal stromal/stem cells as potential therapy in diabetic retinopathy

    Fiori, A., Terlizzi, V., Kremer, H., Gebauer, J., Hammes, H-P., Harmsen, M. C. & Bieback, K. 2-Feb-2018 In : Immunobiology.

    Research output: Scientific - peer-reviewReview article

  3. Epiproteome profiling of cadmium-transformed human bronchial epithelial cells by quantitative histone post-translational modification-enzyme-linked immunosorbent assay

    Liang, Z-L., Wu, D-D., Yao, Y., Yu, F-Y., Yang, L., Tan, H. W., Hylkema, M. N., Rots, M. G., Xu, Y-M. & Lau, A. T. Y. 9-Feb-2018 In : Journal of Applied Toxicology. 8 p.

    Research output: Scientific - peer-reviewArticle

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Press / Media
  1. Interview Volkskrant, following a collision after hypoglycaemia

    Paul Vos, de


    1 media contribution

    Press / Media: Expert Comment

  2. Cancer medication by the roadside

    Wim Quax


    1 item of media coverage

    Press / Media: Research

  3. Pennen breken in borst patiënt

    Prashant Sharma & Tjark Ebels


    1 item of media coverage

    Press / Media: Other

View all (20) »

  1. Ontwikkelingen in de behandeling van Diabetes

    Vos, de, P. (Invited speaker)

    Activity: Talk or presentationInvited talk

  2. Eilandjes transplantatie voor diabetes behandeling

    Vos, de, P. (Keynote speaker)

    Activity: Talk or presentationInvited talk

  3. Op weg naar een toekomst zonder Diabetes

    Vos, de, P. (Keynote speaker)

    Activity: Talk or presentationInvited talk

View all (37) »

  1. ERC Starting Grant: NanoPaths

    Anna Salvati (Recipient), 1-Jul-2015

    Prize: Fellowship awarded competitively

  2. Rosalind Franklin Fellowship

    Romana Schirhagl (Recipient), 2014

    Prize: Fellowship awarded competitively

View all (20) »

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