W.J. Kolff Institute for Biomedical Engineering and Materials Science

University of Groningen > Faculty of Medical Sciences > W.J. Kolff Institute for Biomedical Engineering and Materials Science (KOLFF)

Contact information

Antonius Deusinglaan 1, FB41
9713 AV
Groningen
Netherlands
  • Phone: +31 50 3633140

Organisational unit profile

The W.J. Kolff Institute for Biomedical Engineering and Materials Science was established on October 8th, 1997. The institute is named after Willem Johan Kolff, who as a resident in Groningen, developed the first functioning artificial kidney in the 1940th and saved lives of millions of patients ever since.

The use of biomaterials implants has become an integral part of modern health care in the Western world. Modern health care could not even exist without biomaterials and the restoration of function after oncological surgery, trauma or simply wear due to advanced age would be impossible. With the average life expectancy approaching 80 years, the use of biomaterials will increase due to the demands of the ageing population for a high quality of life.

The mission statement of the W.J. Kolff Institute is to establish a center of expertise for the entire stage of biomedical materials science and its application involving basic materials science, medical product development and clinical evaluation that will contribute to the long-lasting well-being of patients in need of biomaterials implants and extra-corporal support systems.

Research Focus and Strategy

  • Bioadhesion, biocompatibility and infection: Focusses on the prevention of biofilm formation on all biomaterials implants and devices, its aims are formulated with respect to the infection prevention of temporarily and permanent implants and devices.
  • Nanobiotechnology and advanced therapeutic materials: Employs tools from nanobiotechnology to fabricate powerful drug carrier systems and nanoscale surface coatings.
  • Restoring organ function by means of regenerative medicine: Focuses on various aspects of tissue (re) generation, repair and remodelling, including inflammation.
  • Maintaining oral health and oral function: Provides new tools for prevention of oral health disorders to occur and to produce new strategies to restore and maintain oral health and function during life with minimal costs and efforts.

 

Scientific Director

 

Prof. dr. H.C. van der Mei
E-mail: h.c.van.der.mei@umcg.nl
Phone: +31 50 3633140
Fax: +31 50 3633159

 

Publications
  1. Digital assessment of a retentive full crown preparation - an evaluation of prepCheck in an undergraduate preclinical teaching environment

    Schepke, U., van Wulfften Palthe, M. E., Meisberger, E. W., Kerdijk, W., Cune, M. S. & Blok, B., 18-Feb-2020, In : European journal of dental education.

    Research output: Contribution to journalArticleAcademicpeer-review

  2. Single-Molecule Observation of Ligand Binding and Conformational Changes in FeuA

    de Boer, M., Gouridis, G., Muthahari, Y. A. & Cordes, T., 5-Nov-2019, In : Biophysical Journal. 117, 9, p. 1642-1654 13 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. Electrostatically PEGylated DNA enables salt-free hybridization in water

    Chakraborty, G., Balinin, K., Portale, G., Loznik, M., Polushkin, E., Weil, T. & Herrmann, A., 21-Nov-2019, In : Chemical Science. 10, 43, p. 10097-10105 9 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Three-Dimensional Stereophotogrammetry Assessment of Facial Asymmetry in Facial Palsy

    van Veen, M. M., Ten Berge, J. H. A., Werker, P. M. N. & Dijkstra, P. U., 7-Feb-2020, In : Journal of Craniofacial Surgery. 5 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  5. Protective effects of lactic acid bacteria on gut epithelial barrier dysfunction are Toll like receptor 2 and protein kinase C dependent

    Ren, C., Zhang, Q., de Haan, B. J., Faas, M. M., Zhang, H. & de Vos, P., 11-Feb-2020, In : Food & Function.

    Research output: Contribution to journalArticleAcademicpeer-review

View all (5,447) »

Datasets
  1. Dataset: Ovalbumin-containing core-shell implants suitable to obtain a delayed IgG1 antibody response in support of a biphasic pulsatile release profile in mice

    Amssoms, K. (Creator), Born, P. (Creator), Beugeling, M. (Creator), De Clerck, B. (Creator), Van Gulck, E. (Creator), Hinrichs, W. (Creator), Frijlink, E. (Creator), Grasmeijer, N. (Creator), Kraus, G. (Creator), Sutmuller, R. (Creator), Simmen, K. (Creator), Baert, L. (Creator), University of Groningen, 17-Aug-2018

    Dataset

  2. Data for: ColiCoords: A Python package for the analysis of bacterial fluorescence microscopy data

    Smit, J. (Creator), Li, Y. (Creator), Warszawik, E. (Creator), Hermann, A. (Creator), Cordes, T. (Creator), University of Groningen, 12-Apr-2019

    Dataset

  3. Data from: Sialendoscopy enhances salivary gland function in Sjögren’s syndrome: a 6 month follow-up, randomized and controlled, single blind study

    Karagozoglu, K. H. (Creator), Vissink, A. (Creator), Forouzanfar, T. (Creator), Brand, H. S. (Creator), Maarse, F. (Creator), Jager, D. (Creator), University of Groningen, 28-Feb-2018

    Dataset

View all (5) »

Prizes
  1. Distinguished Service Award

    Edwin Winkel (Recipient), 2016

    Prize: National/international honourAcademic

  2. VMTI publicatie prijs

    Albert Hoeksema (Recipient), Sophie Spoorenberg (Recipient), Lilian L. Peters (Recipient), Hendrikus Meijer (Recipient), Gerry Raghoebar (Recipient), Arjan Vissink (Recipient), Klaske Wynia (Recipient) & Anita Visser (Recipient), 6-Oct-2017

    PrizeAcademic

View all (23) »

Activities
  1. 4th European Summer School Nutrigenomics

    Marianne Rots (Invited speaker)
    22-Jun-202026-Jun-2020

    Activity: Participating in or organising an eventOrganising an eventAcademic

  2. EpiBio 2020

    Marianne Rots (Organiser)
    9-Oct-202011-Oct-2020

    Activity: Participating in or organising an eventOrganising an eventAcademic

  3. Week van de Longen

    Janette Burgess (Invited speaker)
    6-Apr-20209-Apr-2020

    Activity: Participating in or organising an eventOrganising an eventProfessional

View all (263) »

Press / Media
  1. Interview on Dutch radio station Radio Noord

    Romana Schirhagl

    11/10/2018

    1 Media contribution

    Press/Media: Public Engagement ActivitiesPopular

  2. Voor het eerst extra gen gericht in lichaam gebouwd

    Marianne Rots

    08/10/2018

    1 item of Media coverage

    Press/Media: Expert CommentPopular

  3. First test of in-body gene editing shows promise

    Marianne Rots

    05/09/2018

    1 item of Media coverage

    Press/Media: Expert CommentPopular

View all (29) »

View graph of relations

ID: 34668