W.J. Kolff Institute for Biomedical Engineering and Materials Science

University of Groningen > Faculty of Medical Sciences > W.J. Kolff Institute for Biomedical Engineering and Materials Science

Contact information

Antonius Deusinglaan 1, FB41
9713 AV
  • Phone: +31 50 3633140

Organisational unit profile

The W.J. Kolff Institute for Biomedical Engineering and Materials Science was established on October 8th, 1997. The institute is named after Willem Johan Kolff, who as a resident in Groningen, developed the first functioning artificial kidney in the 1940th and saved lives of millions of patients ever since.

The use of biomaterials implants has become an integral part of modern health care in the Western world. Modern health care could not even exist without biomaterials and the restoration of function after oncological surgery, trauma or simply wear due to advanced age would be impossible. With the average life expectancy approaching 80 years, the use of biomaterials will increase due to the demands of the ageing population for a high quality of life.

The mission statement of the W.J. Kolff Institute is to establish a center of expertise for the entire stage of biomedical materials science and its application involving basic materials science, medical product development and clinical evaluation that will contribute to the long-lasting well-being of patients in need of biomaterials implants and extra-corporal support systems.

Research Focus and Strategy

  • Bioadhesion, biocompatibility and infection: Focusses on the prevention of biofilm formation on all biomaterials implants and devices, its aims are formulated with respect to the infection prevention of temporarily and permanent implants and devices.
  • Nanobiotechnology and advanced therapeutic materials: Employs tools from nanobiotechnology to fabricate powerful drug carrier systems and nanoscale surface coatings.
  • Restoring organ function by means of regenerative medicine: Focuses on various aspects of tissue (re) generation, repair and remodelling, including inflammation.
  • Maintaining oral health and oral function: Provides new tools for prevention of oral health disorders to occur and to produce new strategies to restore and maintain oral health and function during life with minimal costs and efforts.


Scientific Director


Prof. dr. H.C. van der Mei
E-mail: h.c.van.der.mei@umcg.nl
Phone: +31 50 3633140
Fax: +31 50 3633159


  1. alpha II-spectrin and beta II-spectrin do not affect TGF beta 1-induced myofibroblast differentiation

    Piersma, B., Wouters, O. Y. & Bank, R. A. Oct-2018 In : Cell and Tissue Research. 374, 1, p. 165-175 11 p.

    Research output: Contribution to journalArticle

  2. The mechanism behind the biphasic pulsatile drug release from physically mixed poly(dl-lactic(-co-glycolic) acid)-based compacts

    Beugeling, M., Grasmeijer, N., Born, P. A., van der Meulen, M., van der Kooij, R. S., Schwengle, K., Baert, L., Amssoms, K., Frijlink, H. W. & Hinrichs, W. L. J. 14-Sep-2018 In : International Journal of Pharmaceutics. 551, 1-2, p. 195-202 8 p.

    Research output: Contribution to journalArticle

  3. Cost Effectiveness of Arthrocentesis Compared to Conservative Therapy for Arthralgia of the Temporomandibular Joint: A Randomized Controlled Trial

    Vos, L. M., Stegenga, B., Stant, A. D., Quik, E. H. & Slater, J. J. R. H. 2018 In : Journal of Oral & Facial Pain and Headache. 32, 2, p. 198-207 10 p.

    Research output: Contribution to journalArticle

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  1. Data from: Preoperative characteristics of working-age patients undergoing total knee arthroplasty

    Hylkema, T. (Creator), Stevens, M. (Creator), van Beveren, J. (Creator), Rijk, P. C. (Creator), van Jonbergen, H. W. (Creator), Brouwer, R. (Creator), Bulstra, S. (Creator), Brouwer, S. (Creator), University of Groningen, 29-Aug-2017


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  1. VMTI publicatie prijs

    Arie Hoeksema (Recipient), Sophie Spoorenberg (Recipient), Lilian Peters (Recipient), Hendrikus Meijer (Recipient), Gerry Raghoebar (Recipient), Arjan Vissink (Recipient), Klaske Wynia (Recipient) & Anita Visser (Recipient), 6-Oct-2017


  2. NRLS DAAD Award

    Wim Quax (Recipient), 21-Oct-2016

    Prize: National/international honour

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  1. Pharmacy Day 2018

    Salvati, A. (Organiser), Dolga, A. (Organiser), Groves, M. (Organiser), Mathwig, K. (Organiser), Horvatovich, P. (Organiser), Quax, W. (Organiser), Lexmond, A. (Organiser), Nieuwenhuis-Dempsey, G. (Organiser)

    Activity: ScientificOrganising an event

  2. Joint related neuropathic pain is associated with loss of joint specific function and quality of life within Hip and Knee Osteoarthritis patients

    Blikman, T. (Speaker), Rienstra, W. (Speaker), Remco Kuilman (Speaker), Baukje Dijkstra (Speaker), Josephus van Raay (Speaker), Bulstra, S. (Speaker), Akker-Scheek, van den, I. (Speaker)

    Activity: Talk or presentationInvited talk

  3. The French National Research Agency (ANR) (External organisation)

    Poelstra, K. (Reviewer)

    Activity: ScientificMembership of committee

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Press / Media
  1. Uw bacteriën babbelen voortdurend met elkaar

    Wim Quax


    1 media contribution

    Press/Media: Expert Comment

  2. Interview Volkskrant, following a collision after hypoglycaemia

    Paul Vos, de


    1 media contribution

    Press/Media: Expert Comment

  3. Cancer medication by the roadside

    Wim Quax


    1 item of media coverage

    Press/Media: Research

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