W.J. Kolff Institute for Biomedical Engineering and Materials Science

University of Groningen > Faculteit Medische Wetenschappen/UMCG > W.J. Kolff Institute for Biomedical Engineering and Materials Science (KOLFF)

Contact information

Antonius Deusinglaan 1, FB41
9713 AV
Groningen
Netherlands
  • Phone: +31 50 3633140

Organisational unit profile

The W.J. Kolff Institute for Biomedical Engineering and Materials Science was established on October 8th, 1997. The institute is named after Willem Johan Kolff, who as a resident in Groningen, developed the first functioning artificial kidney in the 1940th and saved lives of millions of patients ever since.

The use of biomaterials implants has become an integral part of modern health care in the Western world. Modern health care could not even exist without biomaterials and the restoration of function after oncological surgery, trauma or simply wear due to advanced age would be impossible. With the average life expectancy approaching 80 years, the use of biomaterials will increase due to the demands of the ageing population for a high quality of life.

The mission statement of the W.J. Kolff Institute is to establish a center of expertise for the entire stage of biomedical materials science and its application involving basic materials science, medical product development and clinical evaluation that will contribute to the long-lasting well-being of patients in need of biomaterials implants and extra-corporal support systems.

Research Focus and Strategy

  • Bioadhesion, biocompatibility and infection: Focusses on the prevention of biofilm formation on all biomaterials implants and devices, its aims are formulated with respect to the infection prevention of temporarily and permanent implants and devices.
  • Nanobiotechnology and advanced therapeutic materials: Employs tools from nanobiotechnology to fabricate powerful drug carrier systems and nanoscale surface coatings.
  • Restoring organ function by means of regenerative medicine: Focuses on various aspects of tissue (re) generation, repair and remodelling, including inflammation.
  • Maintaining oral health and oral function: Provides new tools for prevention of oral health disorders to occur and to produce new strategies to restore and maintain oral health and function during life with minimal costs and efforts.

 

Scientific Director

 

Prof. dr. H.C. van der Mei
E-mail: h.c.van.der.mei@umcg.nl
Phone: +31 50 3633140
Fax: +31 50 3633159

 

Publications
  1. Nanostructured Coating for Biomaterial Lubrication through Biomacromolecular Recruitment

    Wan, H., Zhao, X., Lin, C., Kaper, H. J. & Sharma, P. K., 29-Apr-2020, In : ACS Applied Materials & Interfaces. 12, 21, p. 23726-23736 11 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  2. A bioinspired mucoadhesive restores lubrication of degraded cartilage through reestablishment of lamina splendens

    Wan, H., Ren, K., Kaper, H. J. & Sharma, P. K., 30-Apr-2020, In : Colloids and Surfaces B: Biointerfaces. 193, p. 110977 8 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. Breuksterkte van verschillende types directe en indirecte restauraties bij het functioneel herstel van endodontisch behandelde molaren

    de Kuijper, M. C. F. M., Gresnigt, M. M. M., van den Houten, M., Haumahu, D., Schepke, U. & Cune, M. S., Apr-2020, In : Nederlands tijdschrift voor tandheelkunde. 127, 4, p. 245-253 9 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Osteoprotegerin is More than a Possible Serum Marker in Liver Fibrosis: A Study into its Function in Human and Murine Liver

    Adhyatmika, A., Beljaars, L., Putri, K. S. S., Habibie, H., Boorsma, C. E., Reker-Smit, C., Luangmonkong, T., Guney, B., Haak, A., Mangnus, K. A., Post, E., Poelstra, K., Ravnskjaer, K., Olinga, P. & Melgert, B. N., 2020, In : Pharmaceutics. 12, 5

    Research output: Contribution to journalArticleAcademicpeer-review

View all (5,490) »

Datasets
  1. Dataset: Ovalbumin-containing core-shell implants suitable to obtain a delayed IgG1 antibody response in support of a biphasic pulsatile release profile in mice

    Amssoms, K. (Creator), Born, P. (Creator), Beugeling, M. (Creator), De Clerck, B. (Creator), Van Gulck, E. (Creator), Hinrichs, W. (Creator), Frijlink, E. (Creator), Grasmeijer, N. (Creator), Kraus, G. (Creator), Sutmuller, R. (Creator), Simmen, K. (Creator), Baert, L. (Creator), University of Groningen, 17-Aug-2018

    Dataset

  2. Data for: ColiCoords: A Python package for the analysis of bacterial fluorescence microscopy data

    Smit, J. (Creator), Li, Y. (Creator), Warszawik, E. (Creator), Hermann, A. (Creator), Cordes, T. (Creator), University of Groningen, 12-Apr-2019

    Dataset

  3. Data from: Sialendoscopy enhances salivary gland function in Sjögren’s syndrome: a 6 month follow-up, randomized and controlled, single blind study

    Karagozoglu, K. H. (Creator), Vissink, A. (Creator), Forouzanfar, T. (Creator), Brand, H. S. (Creator), Maarse, F. (Creator), Jager, D. (Creator), University of Groningen, 28-Feb-2018

    Dataset

View all (5) »

Prizes
  1. 3e prijs NT-Verhalenwedstrijd 2019

    Anita Visser (Recipient), 13-Dec-2019

    PrizeProfessional

  2. Consultant at Sangamo Therapeutics Inc

    Marianne Rots (Recipient), 2019

    Prize: National/international honourProfessional

  3. Editor-in-Chief

    Marianne Rots (Recipient), 2019

    Prize: National/international honourAcademic

View all (27) »

Activities
  1. Themabijeenkomst gerodontologie CTM (Event)

    Anita Visser (Chair)
    18-Apr-2019

    Activity: MembershipMembership of committeeAcademic

  2. Congres tandheelkunde

    Anita Visser (Invited speaker)
    13-Dec-2019

    Activity: Participating in or organising an eventParticipation in conferenceAcademic

  3. Voorjaarsvergadering van het Nederlandsch Tandheelkundig Genootschap (NTG) 2019

    Anita Visser (Speaker)
    18-Oct-2019

    Activity: Participating in or organising an eventParticipation in conferenceAcademic

View all (437) »

Press / Media
  1. Zorgen over opstarten orthopedische zorg de achterstand halen we niet snel in

    Sjoerd Bulstra

    01/05/2020

    1 Media contribution

    Press/Media: Public Engagement ActivitiesPopular

  2. Artsen bezorgd over gebruik urgentielijst als triagemiddel.

    Sjoerd Bulstra

    25/04/2020

    1 Media contribution

    Press/Media: Expert CommentAcademic

  3. Aandacht voor de verwaarloosde gebitten van onze ouderen.

    Anita Visser

    01/12/2019

    1 Media contribution

    Press/Media: Expert CommentAcademic

View all (41) »

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