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University of Groningen > KVI - Center for Advanced Radiation Technology > Research unit Medical Physics

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  1. 2018
  2. Nagle, P. W., Hosper, N. A., Barazzuol, L., Jellema, A. L., Baanstra, M., van Goethem, M-J., ... Coppes, R. P. (2018). Lack of DNA Damage Response at Low Radiation Doses in Adult Stem Cells Contributes to Organ Dysfunction. Clinical Cancer Research, 24(24), 6583-6593. https://doi.org/10.1158/1078-0432.CCR-18-0533
  3. van Abbema, J. K., van Goethem, M. -J., Mulder, J., Biegun, A. K., Greuter, M. J. W., van der Schaaf, A., ... van der Graaf, E. R. (2018). High accuracy proton relative stopping power measurement. Nuclear Instruments & Methods in Physics Research Section B-Beam Interactions with Materials and Atoms, 436, 99-106. https://doi.org/10.1016/j.nimb.2018.09.015
  4. Teichmann, T., Torres, M. J. G., van Goethem, M. J., van der Graaf, E. R., Henniger, J., Jahn, A., ... Kormoll, T. (2018). Dose and dose rate measurements in proton beams using the luminescence of beryllium oxide. Journal of Instrumentation, 13, [10015]. https://doi.org/10.1088/1748-0221/13/10/P10015
  5. Us, D., Brzezinski, K., Buitenhuis, T., Dendooven, P., & Ruotsalainen, U. (2018). Evaluation of Median Root Prior for Robust In-Beam PET Reconstruction. IEEE Transactions on Radiation and Plasma Medical Sciences, 2(5), 490-498. https://doi.org/10.1109/TRPMS.2018.2854231
  6. 2017
  7. Juerß, D., Zwar, M., Giesen, U., Nolte, R., Kriesen, S., Baiocco, G., ... Hildebrandt, G. (2017). Comparative study of the effects of different radiation qualities on normal human breast cells. Radiation oncology, 12(1), [159]. https://doi.org/10.1186/s13014-017-0895-8
  8. Biegun, A. K., van Goethem, M-J., van der Graaf, E. R., van Beuzekom, M., Koffeman, E. N., Nakaji, T., ... Brandenburg, S. (2017). The optimal balance between quality and efficiency in proton radiography imaging technique at various proton beam energies: A Monte Carlo study. Physica medica-European journal of medical physics, 41, 141-146. https://doi.org/10.1016/j.ejmp.2017.08.006
  9. Pettersen, H. E. S., Alme, J., Biegun, A., van den Brink, A., Chaar, M., Fehlker, D., ... Rohrich, D. (2017). Proton tracking in a high-granularity Digital Tracking Calorimeter for proton CT purposes. Nuclear instruments & methods in physics research section a-Accelerators spectrometers detectors and associated equipment, 860, 51-61. https://doi.org/10.1016/j.nima.2017.02.007
  10. Diblen, F., Buitenhuis, T., Solf, T., Rodrigues, P., van der Graaf, E., van Goethem, M-J., ... Dendooven, P. (2017). Radiation Hardness of dSiPM Sensors in a Proton Therapy Radiation Environment. IEEE Transactions on Nuclear Science, 64(7), 1891-1896. https://doi.org/10.1109/TNS.2017.2705522
  11. Buitenhuis, HJT., Diblen, F., Brzezinski, KW., Brandenburg, S., & Dendooven, P. (2017). Beam-on imaging of short-lived positron emitters during proton therapy. Physics in Medicine and Biology, 62(12), 4654-4672. https://doi.org/10.1088/1361-6560/aa6b8c
  12. Hamming, V. C., Brouwer, C. L., Goethem, M. J. V., Jolck, R. I., Leijsen, C. V., & Bergh, A. C. M. V. D. (2017). PO-0866: Visibility, image artifacts and proton dose perturbation of fiducial markers. S471 - S472. https://doi.org/10.1016/S0167-8140(17)31303-8
  13. Alia, R. G., Brugger, M., Ferlet-Cavrois, V., Brandenburg, S., Calcutt, J., Cerutti, F., ... Zadeh, A. (2017). Proton Dominance of Sub-LET Threshold GCR SEE Rate. IEEE Transactions on Nuclear Science, 64(1), 388-397. https://doi.org/10.1109/TNS.2016.2628363
  14. van Abbema, J. K. (2017). Accurate relative stopping power prediction from dual energy CT for proton therapy: Methodology and experimental validation. [Groningen]: Rijksuniversiteit Groningen.
  15. Mulder, J. (2017). Water calorimetry for proton therapy: Implementing a primary dose measurement standard. [Groningen]: Rijksuniversiteit Groningen.
  16. 2016
  17. de Meijer, R., van der Graaf, E., & Post, K. (2016). Radiometric properties of marine mammal fossils from the Westerschelde Estuary (Province of Zeeland, the Netherlands). DEINSEA, 16, 10-18.
  18. Biegun, A. K., Takatsu, J., Nakaji, T., van Goethem, M. J., van der Graaf, E. R., Koffeman, E. N., ... Brandenburg, S. (2016). Proton energy and scattering angle radiographs to improve proton treatment planning: a Monte Carlo study. Journal of Instrumentation, 11, [12015]. https://doi.org/10.1088/1748-0221/11/12/C12015
  19. Biegun, A., Takatsu, J., Nakaji, T., van Goethem, M-J., van der Graaf, E., Koffeman, E., ... Brandenburg, S. (2016). Proton energy and scattering angle radiographs to improve proton treatment planning: a Monte Carlo study. Journal of Instrumentation, 11, [C12015]. https://doi.org/10.1088/1748-0221/11/12/C12015
  20. Brzezinski, K., Oliver, J. F., Gillam, J., Rafecas, M., Studen, A., Grkovski, M., ... Clinthorne, N. H. (2016). Experimental evaluation of the resolution improvement provided by a silicon PET probe. Journal of Instrumentation, 11, [09016]. https://doi.org/10.1088/1748-0221/11/09/P09016
  21. Solevi, P., Munoz, E., Solaz, C., Trovato, M., Dendooven, P., Gillam, J. E., ... Llosa, G. (2016). Performance of MACACO Compton telescope for ion-beam therapy monitoring: first test with proton beams. Physics in Medicine and Biology, 61(14), 5149-5165. https://doi.org/10.1088/0031-9155/61/14/5149
  22. Kavatsyuk, O. O., van Goethem, M-J., & Brandenburg, S. (2016). Imaging method and system for verification of a treatment plan in hadron therapy. (Patent No. WO2016099264).
  23. Reiter, M. P., Rink, A. K., Dickel, T., Haettner, E., Heisse, F., Plass, W. R., ... Xu, X. (2016). Rate capability of a cryogenic stopping cell for uranium projectile fragments produced at 1000 MeV/u. Nuclear Instruments & Methods in Physics Research Section B-Beam Interactions with Materials and Atoms, 376, 240-245. https://doi.org/10.1016/j.nimb.2015.12.016
  24. Nagle, P. W., Hosper, N. A., Ploeg, E. M., van Goethem, M-J., Brandenburg, S., Langendijk, J. A., ... Coppes, R. P. (2016). The In Vitro Response of Tissue Stem Cells to Irradiation With Different Linear Energy Transfers. International Journal of Radiation Oncology Biology Physics, 95(1), 103-111. https://doi.org/10.1016/j.ijrobp.2016.02.020
  25. Schlathölter, T., Eustache, P., Porcel, E., Salado, D., Stefancikova, L., Tillement, O., ... Lacombe, S. (2016). Improving proton therapy by metal-containing nanoparticles: Nanoscale insights. International Journal of Nanomedicine, 2016(11), 1549-1556. https://doi.org/10.2147/IJN.S99410
  26. Biegun, A. K., Visser, J., Klaver, T., Ghazanfari, N., van Goethem, M-J., Koffeman, E., ... Brandenburg, S. (2016). Proton Radiography With Timepix Based Time Projection Chambers. Ieee transactions on medical imaging, 35(4), 1099-1105. https://doi.org/10.1109/TMI.2015.2509175
  27. Takatsu, J., van der Graaf, E. R., van Goethem, M-J., Brandenburg, S., & Biegun, A. (2016). From 2D to 3D: Proton Radiography and Proton CT in proton therapy: A simulation study. Radiotherapy and Oncology, 118(Suppl. 1 (15-19 February)), S10-S11. https://doi.org/10.1016/S0167-8140(16)30022-6
  28. Biegun, A., Takatsu, J., van Goethem, M-J., van der Graaf, E., van Beuzekom, M., Visser, J., & Brandenburg, S. (2016). Proton Radiography to Improve Proton Radiotherapy: Simulation Study at Different Proton Beam Energies. Acta Physica Polonica B, 47(2), 329-334. https://doi.org/10.5506/APhysPolB.47.329
  29. Adrian-Martinez, S., Ageron, M., Aharonian, F., Aiello, S., Albert, A., Ameli, F., ... KM3NeT Collaboration (2016). The prototype detection unit of the KM3NeT detector. European Physical Journal C, 76, [54]. https://doi.org/10.1140/epjc/s10052-015-3868-9
  30. van der Veen, S. J., Faber, H., Ghobadi, G., Brandenburg, S., Langendijk, J. A., Coppes, R. P., & van Luijk, P. (2016). Decreasing Irradiated Rat Lung Volume Changes Dose-Limiting Toxicity From Early to Late Effects. International Journal of Radiation Oncology Biology Physics, 94(1), 163-171. https://doi.org/10.1016/j.ijrobp.2015.09.034
  31. Takatsu, J., van der Graaf, E. R., van Goethem, M-J., van Beuzekom, M., Klaver, T., Visser, J., ... Biegun, A. K. (2016). Proton radiography to improve proton therapy treatment. Journal of Instrumentation, 11, [01004]. https://doi.org/10.1088/1748-0221/11/01/C01004
  32. Buitenhuis, H. J. T., Dendooven, P., Biegun, A. K., van der Borden, A. J., Diblen, F., van Goethem, M-J., ... Brandenburg, S. (2016). PET Scanning Protocols for In-Situ Dose Delivery Verification of Proton Therapy. Radiotherapy and Oncology, 118(Suppl. 1 ), S17-S18. https://doi.org/10.1016/S0167-8140(16)30035-4
  33. Dendooven, P., Buitenhuis, H. J. T., Diblen, F., Biegun, A. K., Fiedler, F., van Goethem, M. -J., ... Brandenburg, S. (2016). Short-lived Positron Emitters in Beam-on PET Imaging During Proton Therapy. Radiotherapy and Oncology, 118(Suppl. 1 (15-19 Februari)), S17. https://doi.org/10.1016/S0167-8140(16)30034-2
  34. 2015
  35. Dendooven, P., Buitenhuis, H. J. T., Diblen, F., Heeres, P. N., Biegun, A. K., Fiedler, F., ... Brandenburg, S. (2015). Short-lived positron emitters in beam-on PET imaging during proton therapy. Physics in Medicine and Biology, 60(23), 8923-8947. https://doi.org/10.1088/0031-9155/60/23/8923
  36. van Luijk, P., Pringle, S., Deasy, J. O., Moiseenko, V. V., Faber, H., Hovan, A., ... Coppes, R. P. (2015). Sparing the region of the salivary gland containing stem cells preserves saliva production after radiotherapy for head and neck cancer. Science Translational Medicine, 7(305), [ARTN 305ra147]. https://doi.org/10.1126/scitranslmed.aac4441
  37. Hueso-Gonzalez, F., Biegun, A. K., Dendooven, P., Enghardt, W., Fiedler, F., Golnik, C., ... Pausch, G. (2015). Comparison of LSO and BGO block detectors for prompt gamma imaging in ion beam therapy. Journal of Instrumentation, 10, [09015]. https://doi.org/10.1088/1748-0221/10/09/P09015
  38. Wagenaar, D., van der Graaf, E. R., van der Schaaf, A., & Greuter, M. J. W. (2015). Quantitative Comparison of Commercial and Non-Commercial Metal Artifact Reduction Techniques in Computed Tomography. PLoS ONE, 10(6), [e0127932]. https://doi.org/10.1371/journal.pone.0127932
  39. Buitenhuis, H. J. T., Dendooven, P., Diblen, F., Biegun, A. K., van Goethem, M-J., van der Graaf, E. R., & Brandenburg, S. (2015). The Production of Short-Lived Positron Emitters in Proton Therapy. Medical Physics, 42(6), 3200-3200.
  40. Schumann, A., Petzoldt, J., Dendooven, P., Enghardt, W., Golnik, C., Hueso-Gonzalez, F., ... Fiedler, F. (2015). Simulation and experimental verification of prompt gamma-ray emissions during proton irradiation. Physics in Medicine and Biology, 60(10), 4197-4207. https://doi.org/10.1088/0031-9155/60/10/4197
  41. Dickel, T., Plass, W. R., Andres, S. A. S., Ebert, J., Geissel, H., Haettner, E., ... Xu, X. (2015). First spatial separation of a heavy ion isomeric beam with amultiple-reflection time-of-flight mass spectrometer. Physics letters b, 744, 137-141. https://doi.org/10.1016/j.physletb.2015.03.047
  42. van Abbema, J. K., van Goethem, M-J., Greuter, M. J. W., van der Schaaf, A., Brandenburg, S., & van der Graaf, E. R. (2015). Relative electron density determination using a physics based parameterization of photon interactions in medical DECT. Physics in Medicine and Biology, 60(9), 3825-3846. https://doi.org/10.1088/0031-9155/60/9/3825
  43. Duisterwinkel, E., van Abbema, J. K., van Goethem, M. J., Kawachimaru, R., Paganini, L., van der Graaf, E. R., & Brandenburg, S. (2015). Spectra of clinical CT scanners using a portable Compton spectrometer. Medical Physics, 42(4), 1884-1894. https://doi.org/10.1118/1.4915497
  44. Ranjan, M., Dendooven, P., Purushothaman, S., Dickel, T., Reiter, M. P., Ayet, S., ... Weick, H. (2015). Design, construction and cooling system performance of a prototype cryogenic stopping cell for the Super-FRS at FAIR. Nuclear instruments & methods in physics research section a-Accelerators spectrometers detectors and associated equipment, 770, 87-97. https://doi.org/10.1016/j.nima.2014.09.075
  45. van der Veen, S. J., Ghobadi, G., de Boer, R. A., Faber, H., Cannon, M. V., Nagle, P. W., ... Coppes, R. P. (2015). ACE inhibition attenuates radiation-induced cardiopulmonary damage. Radiotherapy and Oncology, 114(1), 96-103. https://doi.org/10.1016/j.radonc.2014.11.017
  46. Biegun, A. K., Takatsu, J., van Beuzekom, M., van der Graaf, E. R., van Goethem, M-J., Klaver, T., ... Brandenburg, S. (2015). Influence of proton scattering angles on the energy radiograph in proton radiotherapy: A simulation study. In Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2015 IEEE IEEEXplore. https://doi.org/10.1109/NSSMIC.2015.7582188
  47. Nagle, P., Hosper, N., Ploeg, E., van Goethem, M-J., Langendijk, H., Chiu, R., & Coppes, R. (2015). The response of three-dimensional spheroids to particle radiotherapy. Abstract from Annual NVRB Spring Meeting , Utrecht, Netherlands.
  48. 2014
  49. Knopf, A., Nill, S., Yohannes, I., Graeff, C., Dowdell, S., Kurz, C., ... Bert, C. (2014). Challenges of radiotherapy: report on the 4D treatment planning workshop 2013. Physica medica-European journal of medical physics, 30(7), 809-815. https://doi.org/10.1016/j.ejmp.2014.07.341
  50. Golnik, C., Hueso-Gonzalez, F., Muller, A., Dendooven, P., Enghardt, W., Fiedler, F., ... Pausch, G. (2014). Range assessment in particle therapy based on prompt gamma-ray timing measurements. Physics in Medicine and Biology, 59(18), 5399-5422. https://doi.org/10.1088/0031-9155/59/18/5399
  51. Broussard, L. J., Back, H. O., Boswell, M. S., Crowell, A. S., Dendooven, P., Giri, G. S., ... Young, A. R. (2014). Measurement of the Half-Life of the T=1/2 Mirror Decay of Ne-19 and its Implication on Physics Beyond the Standard Model. Physical Review Letters, 112(21), [212301]. https://doi.org/10.1103/PhysRevLett.112.212301
  52. Moore, I. D., Dendooven, P., & Ärje, J. (2014). The IGISOL technique: three decades of developments. Hyperfine Interactions, 223(1-3), 17-62. https://doi.org/10.1007/s10751-013-0871-0
  53. Brandenburg, S., Olko, P., Gales, S. (Ed.), Durante, M. (Ed.), Baroni, G., Bleicher, M., ... Schardt, D. (2014). Hadron Therapy. In A. Bracco, & G-E. Koerner (Eds.), Nuclear Physics for Medicine Nupecc.
  54. Nagle, P., van Goethem, M-J., van Luijk, P., Langendijk, J. A., Coppes, R., & Chiu, R. (2014). Targeting DNA repair to enhance particle radiotherapy treatment. Abstract from 40th Annual meeting of the European Radiation Research Society, Rhodes, Greece.
  55. Dendooven, P., Diblen, F., Buitenhuis, H. J. T., Oxley, D. C., Biegun, A. K., van der Borden, A. J., ... van 't Veld, A. A. (2014). TOF-PET scanner configurations for quality assurance in proton therapy: a patient case study. In TOF-PET scanner configurations for quality assurance in proton therapy: a patient case study (pp. S58-S59)
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