1. 2020
  2. Devarajan, S., Meurer, M., van Roermund, C. W. T., Chen, X., Hettema, E. H., Kemp, S., Knop, M., & Williams, C. (2020). Proteasome-dependent protein quality control of the peroxisomal membrane protein Pxa1p. Biochimica et Biophysica Acta-Biomembranes, 1862(9), [183342]. https://doi.org/10.1016/j.bbamem.2020.183342
  3. Buckley, C. M., Pots, H., Gueho, A., Vines, J. H., Munn, C. J., Phillips, B. A., Gilsbach, B., Traynor, D., Nikolaev, A., Soldati, T., Parnell, A. J., Kortholt, A., & King, J. S. (2020). Coordinated Ras and Rac Activity Shapes Macropinocytic Cups and Enables Phagocytosis of Geometrically Diverse Bacteria. Current Biology, 30(15), 2912-2926.e5. https://doi.org/10.1016/j.cub.2020.05.049
  4. Leemans, M., Galicia, C., Deyaert, E., Daems, E., Krause, L., Paesmans, J., Pardon, E., Steyaert, J., Kortholt, A., Sobott, F., Klostermeier, D., & Versées, W. (2020). Allosteric modulation of the GTPase activity of a bacterial LRRK2 homolog by conformation-specific Nanobodies. Biochemical Journal, 477(7), 1203-1218. https://doi.org/10.1042/BCJ20190843
  5. 2019
  6. Deyaert, E., Leemans, M., Singh, R. K., Gallardo, R., Steyaert, J., Kortholt, A., Lauer, J., & Versées, W. (2019). Structure and nucleotide-induced conformational dynamics of the Chlorobium tepidum Roco protein. Biochemical Journal, 476(1), 51-66. https://doi.org/10.1042/BCJ20180803
  7. Chen, X. (2019). Pex13p degradation in yeast. University of Groningen.
  8. 2018
  9. Wauters, L., Terheyden, S., Gilsbach, B. K., Leemans, M., Athanasopoulos, P. S., Guaitoli, G., Wittinghofer, A., Gloeckner, C. J., Versées, W., & Kortholt, A. (2018). Biochemical and kinetic properties of the complex Roco G-protein cycle. Biological Chemistry, 399(12), 1447-1456. https://doi.org/10.1515/hsz-2018-0227
  10. Terheyden, S. (2018). Structural and biochemical characterization of Roco proteins. University of Groningen.
  11. 2017
  12. Deyaert, E., Wauters, L., Guaitoli, G., Konijnenberg, A., Leemans, M., Terheyden, S., Petrovic, A., Gallardo, R., Nederveen-Schippers, L. M., Athanasopoulos, P. S., Pots, H., Van Haastert, P. J. M., Sobott, F., Gloeckner, C. J., Efremov, R., Kortholt, A., & Versées, W. (2017). A homologue of the Parkinson's disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover. Nature Communications, 8(1), 1-12. [1008]. https://doi.org/10.1038/s41467-017-01103-4
  13. 2016
  14. Guaitoli, G., Raimondi, F., Gilsbach, B. K., Gómez-Llorente, Y., Deyaert, E., Renzi, F., Li, X., Schaffner, A., Jagtap, P. K. A., Boldt, K., von Zweydorf, F., Gotthardt, K., Lorimer, D. D., Yue, Z., Burgin, A., Janjic, N., Sattler, M., Versées, W., Ueffing, M., ... Gloeckner, C. J. (2016). Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts. Proceedings of the National Academy of Sciences of the United States of America, 113(30), E4357-E4366. https://doi.org/10.1073/pnas.1523708113
  15. Skoge, M., Wong, E., Hamza, B., Bae, A., Martel, J., Kataria, R., Keizer-Gunnink, I., Kortholt, A., Van Haastert, P. J. M., Charras, G., Janetopoulos, C., & Irimia, D. (2016). A Worldwide Competition to Compare the Speed and Chemotactic Accuracy of Neutrophil-Like Cells. PLoS ONE, 11(6), [e0154491]. https://doi.org/10.1371/journal.pone.0154491
  16. Khanna, A., Lotfi, P., Chavan, A. J., Montaño, N. M., Bolourani, P., Weeks, G., Shen, Z., Briggs, S. P., Pots, H., Van Haastert, P. J. M., Kortholt, A., & Charest, P. G. (2016). The small GTPases Ras and Rap1 bind to and control TORC2 activity. Scientific Reports, 6, 1-9. [25823]. https://doi.org/10.1038/srep25823
  17. Van Laer, B., Roovers, M., Wauters, L., Kasprzak, J. M., Dyzma, M., Deyaert, E., Singh, R. K., Feller, A., Bujnicki, J. M., Droogmans, L., & Versees, W. (2016). Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue. Nucleic Acids Research, 44(2), 940-953. https://doi.org/10.1093/nar/gkv1369
  18. Khanna, A. (2016). Regulation of TORC2 complex in Dictyostelium discoideum. University of Groningen.
  19. 2015
  20. Gilsbach, B. K., Messias, A. C., Ito, G., Sattler, M., Alessi, D. R., Wittinghofer, A., & Kortholt, A. (2015). Structural Characterization of LRRK2 Inhibitors. Journal of Medicinal Chemistry, 58(9), 3751−3756. https://doi.org/10.1021/jm5018779
  21. Wu, J., Pipathsouk, A., Keizer-Gunnink, A., Fusetti, F., Alkema, W., Liu, S., Altschuler, S., Wu, L., Kortholt, A., & Weiner, O. D. (2015). Homer3 regulates the establishment of neutrophil polarity. Molecular Biology of the Cell, 26(9), 1629-1639. https://doi.org/10.1091/mbc.E14-07-1197
  22. Terheyden, S., Ho, F. Y., Gilsbach, B. K., Wittinghofer, A., & Kortholt, A. (2015). Revisiting the Roco G-protein cycle. Biochemical Journal, 465(1), 139-147. https://doi.org/10.1042/BJ20141095
  23. 2014
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