Cancer Research Center Groningen (CRCG)

University of Groningen > Faculty of Medical Sciences > Cancer Research Center Groningen (CRCG)

Contact information

Ant. Deusinglaan 1
Building 3217 ('de Brug'), Room 7.21
9713 AV
  • Phone: +31 50 363 4734

Organisational unit profile

Fundamental, Clinical and Translational Cancer Research.
The Cancer Research Center Groningen (CRCG) was established in 2012. The aim is to translate fundamental insights in oncogenesis and tumour behaviour from basic research into cancer prevention, improvement of early detection of cancer, and better treatment for cancer patients.

The mission of the CRCG is to clarify the molecular mechanisms that determine malignant transformation in a broad spectrum of tumors and to translate these fundamental insights into improved early detection and treatment of cancers. This will ultimately lead to personalized cancer therapy, thus reducing the unintended side effects of treatment on normal tissues and improving the quality of life of cancer survivors.

The CRCG was founded in 2012 as an independent research institute of the University Medical Center Groningen. Four key research programmes have been established:

  1. Damage and Repair in Cancer Development and Cancer Treatment (DARE);
  2. Guided Treatment in optimal Selected cancer patientsTranslational and Clinical research in Oncology (GUTS);
  3. Stem cells, Aging, Leukemia and Lymphoma (SALL);
  4. TARgeted Gynaecologic Oncology  (TARGON).

These programmes are supported by 60 PIs and 139 PhD or MD/PhD students who participate in the UMCG’s Graduate School of Medical Sciences (GSMS). The various programs are characterized by a strong interaction between basic and translational research programs, as shown by joint research meetings and projects.

  1. Improved assembly and variant detection of a haploid human genome using single-molecule, high-fidelity long reads

    Vollger, M. R., Logsdon, G. A., Audano, P. A., Sulovari, A., Porubsky, D., Peluso, P., Wenger, A. M., Concepcion, G. T., Kronenberg, Z. N., Munson, K. M., Baker, C., Sanders, A. D., Spierings, D. C. J., Lansdorp, P. M., Surti, U., Hunkapiller, M. W. & Eichler, E. E., Mar-2020, In : Annals of Human Genetics. 84, 2, p. 125-140 16 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  2. Biochemically Silent Sympathetic Paraganglioma, Pheochromocytoma, or Metastatic Disease in SDHD Mutation Carriers

    Dreijerink, K. M. A., Rijken, J. A., Compaijen, C. J., Timmers, H. J. L. M., van der Horst-Schrivers, A. N. A., van Leeuwaarde, R. S., van Dam, P. S., Leemans, C. R., van Dam, E. W. C. M., Dickhoff, C., Dommering, C. J., de Graaf, P., Zwezerijnen, G. J. C., van der Valk, P., van Oordt, C. W. M-V. D. H., Hensen, E. F., Corssmit, E. P. M. & Eekhoff, E. M. W., Nov-2019, In : Journal of Clinical Endocrinology & Metabolism. 104, 11, p. 5421-5426 6 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. Visual hallucinations and lifetime use of HPPD-related drugs: Results from a large online survey

    Linszen, M., Kleijer, H. & Sommer, I., 2019, In : European Neuropsychopharmacology. 29, p. S118-S118 2 p.

    Research output: Contribution to journalMeeting AbstractAcademic

  4. Leefstijlinterventie bij obese subfertiele vrouwen

    Mutsaerts, M. A. Q., 1-Jan-2017, In : Nederlands Tijdschrift voor Geneeskunde. 161, 6, 7 p., D916.

    Research output: Contribution to journalReview articleAcademicpeer-review

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  1. Dataset: Total Body Metabolic Tumor Response in ALK Positive Non-Small Cell Lung Cancer Patients Treated with ALK Inhibition

    Kerner, G. (Creator), Koole, M. J. B. (Creator), Bongaerts, A. H. H. (Creator), Pruim, J. (Creator), Groen, H. (Creator), University of Groningen, 23-Apr-2016


  2. Data: Direct chromosome-length haplotyping by single-cell sequencing

    Lansdorp, P. (Creator), Sanders, A. D. (Creator), van Wietmarschen, N. (Creator), Falconer, E. (Creator), Hills, M. (Creator), Spierings, D. (Creator), Bevova, M. (Creator), Guryev, V. (Creator), University of Groningen, 26-Nov-2016


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  1. Marie Curie Award 2010

    Marjolijn Lub-de Hooge (Recipient), 13-Oct-2010


  2. Huizinga medal

    Marjolijn Lub-de Hooge (Recipient), 7-Nov-2019

    Prize: National/international honourAcademic

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  1. Dutch Gynaecology Oncology Group - Symposium DGOG

    Hans Nijman (Organiser)

    Activity: Participating in or organising an eventParticipation in conferenceProfessional

  2. novel molecular and immunological aspects of Hodgkin and diffuse large B-cell lymphoma

    Arjan Diepstra (Invited speaker)

    Activity: Talk or presentationAcademic

  3. Interlymph annual meeting

    Arjan Diepstra (Chair)

    Activity: Participating in or organising an eventParticipation in conferenceAcademic

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Press / Media
  1. Psychiater-echtpaar: ‘We hebben haast. Zieke mensen kunnen geen tien jaar wachten’

    Iris Sommer & Robert Schoevers


    1 Media contribution

    Press/Media: Public Engagement ActivitiesPopular

  2. Kankercellen onder de loep

    Wim Timens & Bert van der Vegt


    1 item of Media coverage

    Press/Media: Public Engagement ActivitiesPopular

  3. Interview Hematon

    Jan Jacob Schuringa


    1 item of Media coverage

    Press/Media: Public Engagement ActivitiesProfessional

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