Cancer Research Center Groningen (CRCG)

University of Groningen > Faculty of Medical Sciences > Cancer Research Center Groningen (CRCG)

Contact information

Ant. Deusinglaan 1
Building 3217 ('de Brug'), Room 7.21
9713 AV
  • Phone: +31 50 363 4734

Organisational unit profile

Fundamental, Clinical and Translational Cancer Research.
The Cancer Research Center Groningen (CRCG) was established in 2012. The aim is to translate fundamental insights in oncogenesis and tumour behaviour from basic research into cancer prevention, improvement of early detection of cancer, and better treatment for cancer patients.

The mission of the CRCG is to clarify the molecular mechanisms that determine malignant transformation in a broad spectrum of tumors and to translate these fundamental insights into improved early detection and treatment of cancers. This will ultimately lead to personalized cancer therapy, thus reducing the unintended side effects of treatment on normal tissues and improving the quality of life of cancer survivors.

The CRCG was founded in 2012 as an independent research institute of the University Medical Center Groningen. Four key research programmes have been established:

  1. Damage and Repair in Cancer Development and Cancer Treatment (DARE);
  2. Guided Treatment in optimal Selected cancer patientsTranslational and Clinical research in Oncology (GUTS);
  3. Stem cells, Aging, Leukemia and Lymphoma (SALL);
  4. TARgeted Gynaecologic Oncology  (TARGON).

These programmes are supported by 60 PIs and 139 PhD or MD/PhD students who participate in the UMCG’s Graduate School of Medical Sciences (GSMS). The various programs are characterized by a strong interaction between basic and translational research programs, as shown by joint research meetings and projects.

  1. Well-differentiated Neuroendocrine Carcinoma of the Larynx: Confusion of Terminology and Uncertainty of Early Studies

    Hunt, J. L., Barnes, L., Triantafyllou, A., Gnepp, D. R., Devaney, K. O., Stenman, G., Halmos, G. B., Bishop, J. A., Skalova, A., Willems, S. M., Hellquist, H., Rinaldo, A. & Ferlito, A., Jul-2019, In : Advances in anatomic pathology. 26, 4, p. 246-250 5 p.

    Research output: Contribution to journalReview articleAcademicpeer-review

  2. Clinical outcomes after surgery for primary aldosteronism: Evaluation of the PASO-investigators' consensus criteria within a worldwide cohort of patients

    Int CoNNsortium Study Grp, Vorselaars, W. M. C. M., van Beek, D-J., Postma, E. L., Spiering, W., Rinkes, I. H. M. B., Valk, G. D. & Vriens, M. R., Jul-2019, In : Surgery. 166, 1, p. 61-68 8 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. Inter-observer variability in target delineation increases during adaptive treatment of head-and-neck and lung cancer

    Apolle, R., Appold, S., Bijl, H. P., Blanchard, P., Bussink, J., Faivre-Finn, C., Khalifa, J., Laprie, A., Lievens, Y., Madani, I., Ruffier, A., de Ruysscher, D., van Elmpt, W. & Troost, E. G. C., 26-Jun-2019, In : ACTA ONCOLOGICA. 8 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Stratification and prediction of remission in first-episode psychosis patients: the OPTiMiSE cohort study (vol 9, 20, 2019)

    OPTIMISE Study Grp, Martinuzzi, E., Barbosa, S., Daoudlarian, D., Ali, W. B. H., Gilet, C., Fillatre, L., Khalfallah, O., Troudet, R., Jamain, S., Fond, G., Sommer, I., Leucht, S., Dazzan, P., McGuire, P., Arango, C., Diaz-Caneja, C. M., Fleischhacker, W., Rujescu, D., Glenthoj, B., Winter, I., Kahn, R. S., Yolken, R., Lewis, S., Drake, R., Davidovic, L., Leboyer, M. & Glaichenhaus, N., 21-Jun-2019, In : Translational Psychiatry. 9, 1 p., 171.

    Research output: Contribution to journalArticleAcademicpeer-review

View all (8,354) »

  1. Dataset: Total Body Metabolic Tumor Response in ALK Positive Non-Small Cell Lung Cancer Patients Treated with ALK Inhibition

    Kerner, G. (Creator), Koole, M. J. B. (Creator), Bongaerts, A. H. H. (Creator), Pruim, J. (Creator), Groen, H. (Creator), University of Groningen, 23-Apr-2016


  2. Data: Direct chromosome-length haplotyping by single-cell sequencing

    Lansdorp, P. (Creator), Sanders, A. D. (Creator), van Wietmarschen, N. (Creator), Falconer, E. (Creator), Hills, M. (Creator), Spierings, D. (Creator), Bevova, M. (Creator), Guryev, V. (Creator), University of Groningen, 26-Nov-2016


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  1. European Laryngological Society Silver Fellowship

    Gyorgy Halmos (Recipient), 2013

    Prize: Fellowship awarded competitivelyAcademic

  2. Personal fellowship of the Dutch Cancer Society to study Palliative Medicine

    An Reyners (Recipient), 2005

    Prize: Fellowship awarded competitivelyAcademic

View all (22) »

  1. Informatiemiddag voor hoofd-hals oncologie patiënten

    Gyorgy Halmos (Invited speaker)

    Activity: Participating in or organising an eventOrganising an eventPopular

  2. Treatment of the eldery head and neck cancer patients

    Gyorgy Halmos (Speaker)

    Activity: Talk or presentationAcademic

  3. Epigenetic Editing: reprogramming nuclear and mitochondrial gene expression

    Marianne Rots (Speaker)

    Activity: Talk or presentationAcademic

View all (569) »

Press / Media
  1. Kankercellen onder de loep

    Wim Timens & Bert Vegt, van der


    1 item of media coverage

    Press/Media: Public Engagement ActivitiesPopular

  2. Interview Hematon

    Jan Jacob Schuringa


    1 item of media coverage

    Press/Media: Public Engagement ActivitiesProfessional

  3. PD-L1 kleuring vereist bij eerstelijnsbehandeling urotheelcarcinoom met pembrolizumab

    Wim Timens


    1 item of media coverage

    Press/Media: Expert CommentProfessional

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