Cancer Research Center Groningen (CRCG)

University of Groningen > Faculty of Medical Sciences > Cancer Research Center Groningen (CRCG)

Contact information

Ant. Deusinglaan 1
Building 3217 ('de Brug'), Room 7.21
9713 AV
  • Phone: +31 50 363 4734

Organisational unit profile

Fundamental, Clinical and Translational Cancer Research.
The Cancer Research Center Groningen (CRCG) was established in 2012. The aim is to translate fundamental insights in oncogenesis and tumour behaviour from basic research into cancer prevention, improvement of early detection of cancer, and better treatment for cancer patients.

The mission of the CRCG is to clarify the molecular mechanisms that determine malignant transformation in a broad spectrum of tumors and to translate these fundamental insights into improved early detection and treatment of cancers. This will ultimately lead to personalized cancer therapy, thus reducing the unintended side effects of treatment on normal tissues and improving the quality of life of cancer survivors.

The CRCG was founded in 2012 as an independent research institute of the University Medical Center Groningen. Four key research programmes have been established:

  1. Damage and Repair in Cancer Development and Cancer Treatment (DARE);
  2. Guided Treatment in optimal Selected cancer patientsTranslational and Clinical research in Oncology (GUTS);
  3. Stem cells, Aging, Leukemia and Lymphoma (SALL);
  4. TARgeted Gynaecologic Oncology  (TARGON).

These programmes are supported by 60 PIs and 139 PhD or MD/PhD students who participate in the UMCG’s Graduate School of Medical Sciences (GSMS). The various programs are characterized by a strong interaction between basic and translational research programs, as shown by joint research meetings and projects.

  1. Lactate dehydrogenase levels and F-18-FDG PET/CT metrics differentiate between mediastinal Hodgkin's lymphoma and primary mediastinal B-cell lymphoma

    Alkhawtani, R. H. M., Noordzij, W., Glaudemans, A. W. J. M., van Rijn, R. S., van der Galien, H. T., Balink, H., Nijland, M., Adams, H. J. A., Huls, G., van Meerten, T. & Kwee, T. C. Jun-2018 In : Nuclear Medicine Communications. 39, 6, p. 572-578 7 p.

    Research output: Contribution to journalArticle

  2. Circulating Haptoglobin and Metabolic Syndrome in Renal Transplant Recipients (vol 7, 14264, 2017)

    Minovic, I., Eisenga, M. F., Riphagen, I. J., van den Berg, E., Kootstra-Ros, J., Frenay, A-R. S., van Goor, H., Rimbach, G., Esatbeyoglu, T., Levy, A. P., Gaillard, C. A. J. M., Geleijnse, J. M., Eggersdorfer, M. L., Navis, G. J., Kema, I. P. & Bakker, S. J. L. 20-Apr-2018 In : Scientific Reports. 8, 1 p., 6501

    Research output: Contribution to journalArticle

  3. Combined HAT/EZH2 modulation leads to cancer-selective cell death

    Petraglia, F., Singh, A. A., Carafa, V., Nebbioso, A., Conte, M., Scisciola, L., Valente, S., Baldi, A., Mandoli, A., Petrizzi, V. B., Ingenito, C., De Falco, S., Cicatiello, V., Apicella, I., Janssen-Megens, E. M., Kim, B., Yi, G., Logie, C., Heath, S., Ruvo, M., Wierenga, A. T. J., Flicek, P., Yaspo, M. L., Della Valle, V., Bernard, O., Tomassi, S., Novellino, E., Feoli, A., Sbardella, G., Gut, I., Vellenga, E., Stunnenberg, H. G., Mai, A., Martens, J. H. A. & Altucci, L. 2018 In : Oncotarget. 9, 39, p. 25630-25646 17 p.

    Research output: Contribution to journalArticle

  4. Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia

    Singh, A. A., Petraglia, F., Nebbioso, A., Yi, G., Conte, M., Valente, S., Mandoli, A., Scisciola, L., Lindeboom, R., Kerstens, H., Janssen-Megens, E. M., Pourfarzad, F., Habibi, E., Berentsen, K., Kim, B., Logie, C., Heath, S., Wierenga, A. T. J., Clarke, L., Flicek, P., Jansen, J. H., Kuijpers, T., Yaspo, M. L., Valle, V. D., Bernard, O., Gut, I., Vellenga, E., Stunnenberg, H. G., Mai, A., Altucci, L. & Martens, J. H. A. 2018 In : Oncotarget. 9, 39, p. 25647-25660 14 p.

    Research output: Contribution to journalArticle

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  1. Mandema-stipendium

    Rudolf Fehrmann (Recipient), 2012

    Prize: Fellowship awarded competitively

  2. MD/PhD scholarship

    Rudolf Fehrmann (Recipient), 2006

    Prize: Fellowship awarded competitively

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  1. Ralf Küppers

    Diepstra, A. (Host)

    Activity: ScientificHosting a visitor

  2. Lung education series:

    Schuuring, E. (Invited speaker)

    Activity: ScientificOrganising an event

  3. European Computer Assisted Liver Surgery Society (ECALSS) (External organisation)

    Jong, de, K. (Member)
    24-Nov-2012 → …

    Activity: ProfessionalMembership of board

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Press / Media
  1. College

    Anke Berg, van den


    1 media contribution

    Press/Media: Public Engagement Activities

  2. Nieuwe ontwikkelingen in hematologie, MDS, AML, translationeel.

    Jan Jacob Schuringa


    1 media contribution

    Press/Media: Public Engagement Activities

  3. Experimentele hematologie verfijnt kijk op leukemie

    Jan Jacob Schuringa


    1 item of media coverage

    Press/Media: Public Engagement Activities

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