Cancer Research Center Groningen (CRCG)
University of Groningen > Faculty of Medical Sciences > Cancer Research Center Groningen (CRCG)
Contact information
- Phone: +31 50 363 4734
- E-mail: crcg@umcg.nl
Organisational unit profile
Fundamental, Clinical and Translational Cancer Research.
The Cancer Research Center Groningen (CRCG) was established in 2012. The aim is to translate fundamental insights in oncogenesis and tumour behaviour from basic research into cancer prevention, improvement of early detection of cancer, and better treatment for cancer patients.
The mission of the CRCG is to clarify the molecular mechanisms that determine malignant transformation in a broad spectrum of tumors and to translate these fundamental insights into improved early detection and treatment of cancers. This will ultimately lead to personalized cancer therapy, thus reducing the unintended side effects of treatment on normal tissues and improving the quality of life of cancer survivors.
The CRCG was founded in 2012 as an independent research institute of the University Medical Center Groningen. Four key research programmes have been established:
- Damage and Repair in Cancer Development and Cancer Treatment (DARE);
- Guided Treatment in optimal Selected cancer patientsTranslational and Clinical research in Oncology (GUTS);
- Stem cells, Aging, Leukemia and Lymphoma (SALL);
- TARgeted Gynaecologic Oncology (TARGON).
These programmes are supported by 60 PIs and 139 PhD or MD/PhD students who participate in the UMCG’s Graduate School of Medical Sciences (GSMS). The various programs are characterized by a strong interaction between basic and translational research programs, as shown by joint research meetings and projects.
Publications
Real world experience and biomarkers of nivolumab in dutch advanced renal-cell carcinoma patients.
Verhaart, S. L., L.-Van Herpen, C. M., Oosting, S., Van der Veldt, A., Osanto, S. & Aarts, M. J. B. 20-May-2018 In : Journal of Clinical Oncology. 36, 15, 1 p.Research output: Contribution to journal › Meeting Abstract
Comparative biodistribution analysis across four different Zr-monoclonal antibody tracers-The first step towards an imaging warehouse
Bensch, F., Smeenk, M. M., van Es, S. C., de Jong, J. R., Schröder, C. P., Oosting, S. F., Lub-de Hooge, M. N., Menke-van der Houven van Oordt, C. W., Brouwers, A. H., Boellaard, R. & de Vries, E. G. E. 2018 In : Theranostics. 8, 16, p. 4295-4304 10 p.Research output: Contribution to journal › Article
Robustness and organ sparing potential of intensity modulated proton therapy for lung cancer
Van der Laan, H. P., Anakotta, R. M., Korevaar, E. W., Dieters, M., Ubbels, J. F., Langendijk, J. A., Muijs, C. T. & Knopf, A. C. Apr-2018 In : Radiotherapy and Oncology. 127, p. S1038-S1039 2 p.Research output: Contribution to journal › Meeting Abstract
Multi-scenario robustness evaluation; transition to a 'proton proof' alternative to PTV evaluation
Korevaar, E. W., Scandurra, D., Gelderman, M., Kierkels, R. G., Knopf, A. C., Both, S., Unipan, M., Eenink, M. G. C. & Langendijk, J. A. Apr-2018 In : Radiotherapy and Oncology. 127, p. S1073-S1074 2 p.Research output: Contribution to journal › Meeting Abstract
Robust optimization (4D) IMPT strategies using full and empty bladder CT scans for cervical cancer
Brouwer, C. L., Matysiak, W. P., De Boer, P., Langendijk, J. A., Beukema, J. C. & Both, S. Apr-2018 In : Radiotherapy and Oncology. 127, p. S1118-S1119 2 p.Research output: Contribution to journal › Meeting Abstract
Datasets
Data from: Performance and agreement of risk stratification instruments for postoperative delirium in persons aged 50 years or older
Jansen, C. (Creator), Absalom, A. (Creator), Bock, de, T. (Creator), Leeuwen, van, B. (Creator), Izaks, G. (Creator), University of Groningen, 3-Dec-2014
DOI: https://doi.org/10.5061/dryad.51q03
Dataset
Dataset: Inter-laboratory agreement of the Cervista HPV HR test with a second cut-off at default setting of 1.93 (A) and at new setting of 5.0 (B)
Boers, A. (Creator), Slagter-Menkema, L. (Creator), Hemel, van, B. (Creator), Belinson, J. L. (Creator), Ruitenbeek, T. (Creator), Buikema, H. J. (Creator), Klip, H. (Creator), Ghyssaert, H. (Creator), Zee, van der, A. (Creator), Bock, de, T. (Creator), Schuurs-Wisman, B. (Creator), Schuuring, E. (Creator), University of Groningen, 22-Jul-2014
DOI: https://doi.org/10.1371/journal.pone.0101930.t006
Dataset
Prizes
Understanding the cause of ataxia in the DNA repair deficiency syndrome Ataxia Telangiectasia: a possible link between DNA damage and proteostasis
Steven Bergink (Recipient), 2013
Prize: Fellowship awarded competitively
Activities
Alphavirus-based vaccines from benchto bedside
Daemen, T. (Speaker)13-Sep-2018Activity: Talk or presentation › Invited talk
IAEA (External organisation)
Elsinga, P. (Member)25-Apr-2018 → 25-Apr-2022Activity: Professional › Membership of committee
NVGCT Nederlandse Vereniging voor Gen- en Celtherapie (External organisation)
Daemen, T. (Member)2018 → 2020Activity: Scientific › Membership of committee
Press / Media
Nieuwe ontwikkelingen in hematologie, MDS, AML, translationeel.
22/11/2017
1 media contribution
Press/Media: Public Engagement Activities
Experimentele hematologie verfijnt kijk op leukemie
01/10/2017
1 item of media coverage
Press/Media: Public Engagement Activities
ID: 12296270