Cancer Research Center Groningen (CRCG)
University of Groningen > Faculty of Medical Sciences > Cancer Research Center Groningen (CRCG)
Contact information
- Phone: +31 50 363 4734
- E-mail: crcg@umcg.nl
Organisational unit profile
Fundamental, Clinical and Translational Cancer Research.
The Cancer Research Center Groningen (CRCG) was established in 2012. The aim is to translate fundamental insights in oncogenesis and tumour behaviour from basic research into cancer prevention, improvement of early detection of cancer, and better treatment for cancer patients.
The mission of the CRCG is to clarify the molecular mechanisms that determine malignant transformation in a broad spectrum of tumors and to translate these fundamental insights into improved early detection and treatment of cancers. This will ultimately lead to personalized cancer therapy, thus reducing the unintended side effects of treatment on normal tissues and improving the quality of life of cancer survivors.
The CRCG was founded in 2012 as an independent research institute of the University Medical Center Groningen. Four key research programmes have been established:
- Damage and Repair in Cancer Development and Cancer Treatment (DARE);
- Guided Treatment in optimal Selected cancer patientsTranslational and Clinical research in Oncology (GUTS);
- Stem cells, Aging, Leukemia and Lymphoma (SALL);
- TARgeted Gynaecologic Oncology (TARGON).
These programmes are supported by 60 PIs and 139 PhD or MD/PhD students who participate in the UMCG’s Graduate School of Medical Sciences (GSMS). The various programs are characterized by a strong interaction between basic and translational research programs, as shown by joint research meetings and projects.
Publications
Three-dimensional facial volume analysis using algorithm-based personalized aesthetic templates
Tuin, A. J., Meulstee, J. W., Loonen, T. G. J., Kraeima, J., Spijkervet, F. K. L., Vissink, A., Jansma, J. & Schepers, R. H., 17-Feb-2020, In : International Journal of Oral and Maxillofacial Surgery.Research output: Contribution to journal › Article › Academic › peer-review
Improved assembly and variant detection of a haploid human genome using single-molecule, high-fidelity long reads
Vollger, M. R., Logsdon, G. A., Audano, P. A., Sulovari, A., Porubsky, D., Peluso, P., Wenger, A. M., Concepcion, G. T., Kronenberg, Z. N., Munson, K. M., Baker, C., Sanders, A. D., Spierings, D. C. J., Lansdorp, P. M., Surti, U., Hunkapiller, M. W. & Eichler, E. E., Mar-2020, In : Annals of Human Genetics. 84, 2, p. 125-140 16 p.Research output: Contribution to journal › Article › Academic › peer-review
Biochemically Silent Sympathetic Paraganglioma, Pheochromocytoma, or Metastatic Disease in SDHD Mutation Carriers
Dreijerink, K. M. A., Rijken, J. A., Compaijen, C. J., Timmers, H. J. L. M., van der Horst-Schrivers, A. N. A., van Leeuwaarde, R. S., van Dam, P. S., Leemans, C. R., van Dam, E. W. C. M., Dickhoff, C., Dommering, C. J., de Graaf, P., Zwezerijnen, G. J. C., van der Valk, P., van Oordt, C. W. M-V. D. H., Hensen, E. F., Corssmit, E. P. M. & Eekhoff, E. M. W., Nov-2019, In : Journal of Clinical Endocrinology & Metabolism. 104, 11, p. 5421-5426 6 p.Research output: Contribution to journal › Article › Academic › peer-review
Visual hallucinations and lifetime use of HPPD-related drugs: Results from a large online survey
Linszen, M., Kleijer, H. & Sommer, I., 2019, In : European Neuropsychopharmacology. 29, p. S118-S118 2 p.Research output: Contribution to journal › Meeting Abstract › Academic
Leefstijlinterventie bij obese subfertiele vrouwen
Mutsaerts, M. A. Q., 1-Jan-2017, In : Nederlands Tijdschrift voor Geneeskunde. 161, 6, 7 p., D916.Research output: Contribution to journal › Review article › Academic › peer-review
Datasets
Replication data to: Cortisol and α-amylase secretion patterns between and within depressed and non-depressed individuals.
Booij, S. (Creator), Bos, E. (Creator), Bouwmans, M. (Creator), Kema, I. (Creator), University of Groningen, 6-Jul-2015
DOI: https://doi.org/10411/C8LWAC, https://doi.org/10.1371/journal.pone.0131002.s013
Dataset
Dataset: Total Body Metabolic Tumor Response in ALK Positive Non-Small Cell Lung Cancer Patients Treated with ALK Inhibition
Kerner, G. (Creator), Koole, M. J. B. (Creator), Bongaerts, A. H. H. (Creator), Pruim, J. (Creator), Groen, H. (Creator), University of Groningen, 23-Apr-2016
DOI: https://doi.org/10.6084/m9.figshare.3189766.v1
Dataset
Data: Direct chromosome-length haplotyping by single-cell sequencing
Lansdorp, P. (Creator), Sanders, A. D. (Creator), van Wietmarschen, N. (Creator), Falconer, E. (Creator), Hills, M. (Creator), Spierings, D. (Creator), Bevova, M. (Creator), Guryev, V. (Creator), University of Groningen, 26-Nov-2016
DOI: https://doi.org/10.5281/zenodo.599901
Dataset
Prizes
Huizinga medal
Marjolijn Lub-de Hooge (Recipient), 7-Nov-2019
Prize: National/international honour › Academic
Best paper of the year at annual Dutch Hematology Congress 2019
Jan Jacob Schuringa (Recipient), 2019
Prize › Academic
Activities
Dutch Gynaecology Oncology Group - Symposium DGOG
Hans Nijman (Organiser)23-Jan-2019Activity: Participating in or organising an event › Participation in conference › Professional
novel molecular and immunological aspects of Hodgkin and diffuse large B-cell lymphoma
Arjan Diepstra (Invited speaker)16-Oct-2019Activity: Talk or presentation › Academic
Interlymph annual meeting
Arjan Diepstra (Chair)25-Jun-2019Activity: Participating in or organising an event › Participation in conference › Academic
Press / Media
Psychiater-echtpaar: ‘We hebben haast. Zieke mensen kunnen geen tien jaar wachten’
Iris Sommer & Robert Schoevers
19/09/2019
1 Media contribution
Press/Media: Public Engagement Activities › Popular
Kankercellen onder de loep
Wim Timens & Bert van der Vegt
16/04/2019
1 item of Media coverage
Press/Media: Public Engagement Activities › Popular
Interview Hematon
04/04/2019
1 item of Media coverage
Press/Media: Public Engagement Activities › Professional
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