Cancer Research Center Groningen (CRCG)

University of Groningen > Faculteit Medische Wetenschappen/UMCG > Cancer Research Center Groningen (CRCG)

Contact information

Ant. Deusinglaan 1
Building 3217 ('de Brug'), Room 7.21
9713 AV
  • Phone: +31 50 363 4734

Organisational unit profile

Fundamental, Clinical and Translational Cancer Research.
The Cancer Research Center Groningen (CRCG) was established in 2012. The aim is to translate fundamental insights in oncogenesis and tumour behaviour from basic research into cancer prevention, improvement of early detection of cancer, and better treatment for cancer patients.

The mission of the CRCG is to clarify the molecular mechanisms that determine malignant transformation in a broad spectrum of tumors and to translate these fundamental insights into improved early detection and treatment of cancers. This will ultimately lead to personalized cancer therapy, thus reducing the unintended side effects of treatment on normal tissues and improving the quality of life of cancer survivors.

The CRCG was founded in 2012 as an independent research institute of the University Medical Center Groningen. Four key research programmes have been established:

  1. Damage and Repair in Cancer Development and Cancer Treatment (DARE);
  2. Guided Treatment in optimal Selected cancer patientsTranslational and Clinical research in Oncology (GUTS);
  3. Stem cells, Aging, Leukemia and Lymphoma (SALL);
  4. TARgeted Gynaecologic Oncology  (TARGON).

These programmes are supported by 60 PIs and 139 PhD or MD/PhD students who participate in the UMCG’s Graduate School of Medical Sciences (GSMS). The various programs are characterized by a strong interaction between basic and translational research programs, as shown by joint research meetings and projects.

  1. Towards a benchmark of abdominal CT use during duty shifts: 15-year sample from the Netherlands

    Mengou, I. V., Yakar, D., Kasalak, Ö. & Kwee, T. C., 2020, In : Abdominal radiology (New York).

    Research output: Contribution to journalArticleAcademicpeer-review

  2. PET and SPECT in Neurology (Second Edition)

    Dierckx, R., Otte, A., de Vries, E. F., van Waarde, A. & Leenders, N., 21-Nov-2020, 2 ed. Basel: Springer Nature. 1289 p.

    Research output: Book/ReportBookAcademicpeer-review

  3. Greater male than female variability in regional brain structure across the lifespan

    Karolinska Schizophrenia Project (KaSP) consortium, 2020, In : Human brain mapping.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Discontinuation of antipsychotic medication-time to rethink trial design

    Speyer, H., Begemann, M., Albert, N., Weller, A., Nordentoft, M., Veling, W., Sommer, I. E., Allott, K. & Killackey, E., Oct-2020, In : The Lancet. Psychiatry. 7, 10, p. 841-842 2 p.

    Research output: Contribution to journalArticleAcademicpeer-review

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  1. Dataset: Total Body Metabolic Tumor Response in ALK Positive Non-Small Cell Lung Cancer Patients Treated with ALK Inhibition

    Kerner, G. (Creator), Koole, M. J. B. (Creator), Bongaerts, A. H. H. (Creator), Pruim, J. (Creator), Groen, H. (Creator), University of Groningen, 23-Apr-2016


  2. Data: Direct chromosome-length haplotyping by single-cell sequencing

    Lansdorp, P. (Creator), Sanders, A. D. (Creator), van Wietmarschen, N. (Creator), Falconer, E. (Creator), Hills, M. (Creator), Spierings, D. (Creator), Bevova, M. (Creator), Guryev, V. (Creator), University of Groningen, 26-Nov-2016


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  1. ZonMW-VIDI Committee

    Marianne Rots (Recipient), 2020

    Prize: AppointmentAcademic

  2. Management Committee International Nucleome Consortium

    Marianne Rots (Recipient), 2020

    Prize: National/international honourAcademic

  3. Editor in Chief Epigenetics Communication

    Marianne Rots (Recipient), 8-Oct-2020

    Prize: AppointmentAcademic

View all (39) »

  1. Jose Manuel Rodrigo Muñoz

    Marianne Rots (Host)

    Activity: Hosting a visitorAcademic

  2. Epigenetic editing: contexts matter

    Marianne Rots (Speaker)

    Activity: Talk or presentationAcademic

  3. NABON (External organisation)

    John Maduro (Member)
    2015 → …

    Activity: MembershipMembership of boardProfessional

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Press / Media
  1. Laten testen of je erfelijk belast bent?

    Jan Oosterwijk


    1 Media contribution

    Press/Media: Expert CommentPopular

  2. Protonentherapie is soms zinvoller dan gewone bestraling

    Johannes Albertus Langendijk


    2 Media contributions

    Press/Media: Public Engagement ActivitiesPopular

  3. Moleculaire processen zichtbaar maken met PET

    Erik Vries, de


    1 Media contribution

    Press/Media: ResearchProfessional

View all (138) »

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