Cancer Research Center Groningen (CRCG)

University of Groningen > Faculty of Medical Sciences > Cancer Research Center Groningen (CRCG)

Contact information

Ant. Deusinglaan 1
Building 3217 ('de Brug'), Room 7.21
9713 AV
  • Phone: +31 50 363 4734

Organisational unit profile

Fundamental, Clinical and Translational Cancer Research.
The Cancer Research Center Groningen (CRCG) was established in 2012. The aim is to translate fundamental insights in oncogenesis and tumour behaviour from basic research into cancer prevention, improvement of early detection of cancer, and better treatment for cancer patients.

The mission of the CRCG is to clarify the molecular mechanisms that determine malignant transformation in a broad spectrum of tumors and to translate these fundamental insights into improved early detection and treatment of cancers. This will ultimately lead to personalized cancer therapy, thus reducing the unintended side effects of treatment on normal tissues and improving the quality of life of cancer survivors.

The CRCG was founded in 2012 as an independent research institute of the University Medical Center Groningen. Four key research programmes have been established:

  1. Damage and Repair in Cancer Development and Cancer Treatment (DARE);
  2. Guided Treatment in optimal Selected cancer patientsTranslational and Clinical research in Oncology (GUTS);
  3. Stem cells, Aging, Leukemia and Lymphoma (SALL);
  4. TARgeted Gynaecologic Oncology  (TARGON).

These programmes are supported by 60 PIs and 139 PhD or MD/PhD students who participate in the UMCG’s Graduate School of Medical Sciences (GSMS). The various programs are characterized by a strong interaction between basic and translational research programs, as shown by joint research meetings and projects.

  1. Dried Blood Spot Analysis for Therapeutic Drug Monitoring of Clozapine

    Geers, L. M., Cohen, D., Wehkamp, L. M., van Hateren, K., Koster, R. A., Fedorenko, O. Y., Semke, A. V., Bokhan, N., Ivanova, S. A., Kosterink, J. G. W., Loonen, A. J. M. & Touw, D. J. 2017 In : Journal of Clinical Psychiatry. 78, 9, p. E1211-E1218 8 p.

    Research output: Scientific - peer-reviewArticle

  2. Psychosocial development in survivors of childhood differentiated thyroid carcinoma: a cross-sectional study

    Nies, M., Dekker, B. L., Sulkers, E., Huizinga, G. A., Klein Hesselink, M., Maurice-Stam, H., Grootenhuis, M. A., Brouwers, A., Burgerhof, J. G., van Dam, E. W. C. M., Havekes, B., van den Heuvel-Eibrink, M. M., Corssmit, E. P., Kremer, L. C., Netea-Maier, R., van der Pal, H. H. J., Peeters, R. P., Plukker, J. T., Ronckers, C., van Santen, H. M., van der Horst-Schrivers, A. N. A., Tissing, W. J. E., Bocca, G. & Links, T. P. 18-Dec-2017 In : European Journal of Endocrinology.

    Research output: ScientificArticle

  3. The effect of physical activity on fatigue among survivors of colorectal cancer: a systematic review and meta-analysis

    Brandenbarg, D., Korsten, J. H. W. M., Berger, M. Y. & Berendsen, A. J. Feb-2018 In : Supportive Care in Cancer. 26, 2, p. 393-403 11 p.

    Research output: Scientific - peer-reviewReview article

  4. Treatment of sporadic Burkitt lymphoma in adults, a retrospective comparison of four treatment regimens

    Oosten, L. E. M., Chamuleau, M. E. D., Thielen, F. W., de Wreede, L. C., Siemes, C., Doorduijn, J. K., Smeekes, O. S., Kersten, M. J., Hardi, L., Baars, J. W., Demandt, A. M. P., Stevens, W. B. C., Nijland, M., van Imhoff, G. W., Brouwer, R., Uyl-de Groot, C. A., Kluin, P. M., de Jong, D. & Veelken, H. Feb-2018 In : Annals of Hematology. 97, 2, p. 255-266 12 p.

    Research output: Scientific - peer-reviewArticle

  5. A p300 and SIRT1 Regulated Acetylation Switch of C/EBPα Controls Mitochondrial Function

    Zaini, M. A., Müller, C., de Jong, T. V., Ackermann, T., Hartleben, G., Kortman, G., Gührs, K-H., Fusetti, F., Krämer, O. H., Guryev, V. & Calkhoven, C. F. 9-Jan-2018 In : Cell reports. 22, 2, p. 497-511 15 p.

    Research output: Scientific - peer-reviewArticle

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  1. Karl Musshoff Prize

    Arjan Diepstra (Recipient), 24-Oct-2016


  2. ERC consolidator grant

    Jan Schuringa (Recipient), 2012

    Prize: Fellowship awarded competitively


    Jan Schuringa (Recipient), 2009

    Prize: Fellowship awarded competitively

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  1. Persoonlijk en precies

    Schuringa, J. (Speaker)

    Activity: Talk or presentationInvited talk

  2. workshop immunotherapies Grand Ouest: Infection and Cancer

    Daemen, T. (Invited speaker)

    Activity: Talk or presentationInvited talk

  3. 3rd Symposium on Advances in Cancer Immunology and Immunotherapy, Athens

    Daemen, T. (Invited speaker)

    Activity: Talk or presentationInvited talk

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Press / Media
  1. Nieuwe ontwikkelingen in hematologie, MDS, AML, translationeel.

    Jan Schuringa


    1 media contribution

    Press / Media: Public Engagement Activities

  2. Experimentele hematologie verfijnt kijk op leukemie

    Jan Schuringa


    1 item of media coverage

    Press / Media: Public Engagement Activities

  3. Macrofagen herprogrammeren voor effectievere immuuntherapie

    Toos Daemen


    1 item of media coverage

    Press / Media: Public Engagement Activities

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