MedChemCommun, 2040-2503
Journal
1 - 12 out of 12Page size: 50
- 2018
- 2017
- Shaabani, S., Neochoritis, C. G., Twarda-Clapa, A., Musielak, B., Holak, T. A., & Domling, A. (2017). Scaffold hopping via ANCHOR.QUERY: beta-lactams as potent p53-MDM2 antagonists. MedChemCommun, 8(5), 1046-1052. https://doi.org/10.1039/c7md00058h
- Swier, L. J. Y. M., Monjas, L., Reeßing, F., Oudshoorn, R. C., Aisyah, A., Primke, T., Bakker, M. M., Van Olst, E., Ritschel, T., Faustino, I., Marrink, S. J., Hirsch, A. K. H., & Slotboom, D. J. (2017). Insight into the complete substrate-binding pocket of ThiT by chemical and genetic mutations. MedChemCommun, 8(5), 1121-1130. https://doi.org/10.1039/C7MD00079K
- 2016
- Ourailidou, M. E., Leus, N. G. J., Krist, K., Lenoci, A., Mai, A., & Dekker, F. J. (2016). Chemical epigenetics to assess the role of HDAC1-3 inhibition in macrophage pro-inflammatory gene expression. MedChemCommun, 7(11), 2184-2190. https://doi.org/10.1039/c6md00375c
- Ourailidou, M. E., Zwinderman, M. R. H., & Dekker, F. (2016). Bioorthogonal metabolic labelling with acyl-CoA reporters: targeting protein acylation. MedChemCommun, 7(3), 399-408. https://doi.org/10.1039/c5md00446b
- Monjas , L., Swier, L. J. Y. M., de Voogd, A. R., Oudshoorn, R. C., Hirsch, A. K. H., & Slotboom, D. J. (2016). Design and synthesis of thiamine analogues to study their binding to the ECF transporter for thiamine in bacteria. MedChemCommun, 7(5), 966-971. https://doi.org/10.1039/c6md00022c
- 2015
- Mondal, M., Groothuis, D. E., & Hirsch, A. K. H. (2015). Fragment growing exploiting dynamic combinatorial chemistry of inhibitors of the aspartic protease endothiapepsin. MedChemCommun, 6(7), 1267-1271. https://doi.org/10.1039/c5md00157a
- 2014
- de Almeida, A., Soveral, G., & Casini, A. (2014). Gold compounds as aquaporin inhibitors: New opportunities for therapy and imaging. MedChemComm, 5(10), 1444-1453. https://doi.org/10.1039/c4md00265b
- Serratice, M., Bertrand, B., Janssen, E. F. J., Hemelt, E., Zucca, A., Cocco, F., Cinellu, M. A., & Casini, A. (2014). Gold(I) compounds with lansoprazole-type ligands: synthesis, characterization and anticancer properties in vitro. MedChemComm, 5(9), 1418-1422. https://doi.org/10.1039/c4md00241e
- Boltjes, A., Liao, G. P., Zhao, T., Herdtweck, E., & Doemling, A. (2014). Ugi 4-CR synthesis of gamma- and delta-lactams providing new access to diverse enzyme interactions: a PDB analysis. MedChemCommun, 5(7), 949-952. https://doi.org/10.1039/C4MD00162A
- 2011
- Khoury, K., Popowicz, G. M., Holak, T. A., & Doemling, A. (2011). The p53-MDM2/MDMX axis - A chemotype perspective. MedChemComm, 2(4), 246-260. https://doi.org/10.1039/c0md00248h
- Gabbiani, C., Mastrobuoni, G., Sorrentino, F., Dani, B., Rigobello, M. P., Bindoli, A., Cinellu, M. A., Pieraccini, G., Messori, L., & Casini, A. (2011). Thioredoxin reductase, an emerging target for anticancer metallodrugs. Enzyme inhibition by cytotoxic gold(III) compounds studied with combined mass spectrometry and biochemical assays. MedChemComm, 2(1), 50-54. https://doi.org/10.1039/c0md00181c
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