Trismus in head and neck cancer patients

van der Geer, J., 2020, [Groningen]: Rijksuniversiteit Groningen. 196 p.

Research output: ThesisThesis fully internal (DIV)Academic

Copy link to clipboard


  • Title and contents

    Final publisher's version, 260 KB, PDF document

  • Chapter 1

    Final publisher's version, 242 KB, PDF document

  • Chapter 2

    Final publisher's version, 371 KB, PDF document

  • Chapter 3a

    Final publisher's version, 375 KB, PDF document

  • Chapter 3b

    Final publisher's version, 276 KB, PDF document

    Embargo ends: 03/02/2021

    Request copy

  • Chapter 4

    Final publisher's version, 547 KB, PDF document

  • Chapter 5

    Final publisher's version, 719 KB, PDF document

    Embargo ends: 03/02/2021

    Request copy

  • Chapter 6

    Final publisher's version, 460 KB, PDF document

  • Chapter 7

    Final publisher's version, 266 KB, PDF document

  • Appendices

    Final publisher's version, 508 KB, PDF document

  • Complete thesis

    Final publisher's version, 2 MB, PDF document

    Embargo ends: 03/02/2021

    Request copy

  • Propositions

    Final publisher's version, 97 KB, PDF document

Trismus, a restricted mouth opening, is common among head and neck cancer patients. Head and neck cancer patients experience trismus as one of the three most burdensome side-effects after their cancer treatment. Patients are most likely to experience a restriction in functioning if the mouth opening is 35 millimeter or less.
The development of trismus is most likely, when the mouth opening before treatment is small already, when risk structures (such as the masticatory muscles and the temporomandibular joint) are affected, and when the treatment is extensive (for instance a combination of treatment modalities or a high radiation dose) . Especially during the first six to twelve months after cancer treatment, the chance of developing trismus is high.
To prevent or treat trismus, exercise therapy using stretching devices (such as the TheraBite® Jaw Motion Rehabilitation System™ and the Dynasplint Trismus System®) is often given. However, it seems that exercise therapy using these stretching devices is challenging, because of negative side-effects of stretching, the intensive and burdensome exercise protocol, and limitations of the stretching devices.
In order to improve therapy for trismus or to prevent trismus in the future, factors negatively influencing mouth opening should be minimized, and the effectiveness of therapy for trismus should be optimized.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
Award date3-Feb-2020
Place of Publication[Groningen]
Print ISBNs978-94-034-2295-4
Electronic ISBNs978-94-034-2296-1
Publication statusPublished - 2020

View graph of relations

ID: 112040321