Publication

Effect of Systolic Blood Pressure on Left Ventricular Structure and Function A Mendelian Randomization Study

Hendriks, T., Said, M. A., Janssen, L. M. A., van der Ende, M. Y., van Veldhuisen, D. J., Verweij, N. & van der Harst, P., Oct-2019, In : Hypertension. 74, 4, p. 826-832 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

We aimed to estimate the effects of a lifelong exposure to high systolic blood pressure (SBP) on left ventricular (LV) structure and function using Mendelian randomization. A total of 5596 participants of the UK Biobank were included for whom cardiovascular magnetic resonance imaging and genetic data were available. Major exclusion criteria included nonwhite ethnicity, major cardiovascular disease, and body mass index >30 or

Original languageEnglish
Pages (from-to)826-832
Number of pages7
JournalHypertension
Volume74
Issue number4
Publication statusPublished - Oct-2019

    Keywords

  • biomarker, blood pressure, body surface area, cardiovascular disease, hypertrophy, GENOME-WIDE ASSOCIATION, GENETIC PREDISPOSITION, EJECTION FRACTION, REFERENCE VALUES, RISK-FACTOR, VARIANTS, MASS, METAANALYSIS, HYPERTROPHY, GEOMETRY

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