Research interests

I am a professor of Lifecourse Epidemiology of Common Mental Disorders. Being trained as an (experimental) psychologist, (bio)statistician and epidemiologist, I have always worked on the crossroads of medical and social sciences. My affinity with multi- and interdisciplinary research is reflected in my leadership of the Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), which performs research at the junction of various disciplines, with the aim to unravel psychobiological processes involved in the onset and course of common mental problems, in particular affective disorders. In addition, I am principal investigator of the longitudinal study TRAILS (Tracking Adolescents’ Individual Lives Survey,, which was set up over fourteen years ago to chart and explain the mental health and development of adolescents and young adults, and involves researchers working in various scientific domains and institutes in the Netherlands and abroad.

My inspiration as a scientist is driven by a great deal of curiosity as well as the desire to better understand and predict the intricacies of the onset of course of mental health problems in order to improve prevention and care. My research mainly focuses on the interplay of individual psychobiological vulnerability and resilience factors, conceived as the result of genetic endowment and past experiences, and environmental challenges in the development and course of depressive symptoms. This work is based on observational data collected in large longitudinal epidemiological surveys, complemented with studies involving many repeated measurements in smaller groups to assess temporal patterns of specific mood-related factors and the effects of interventions thereon. An example of such a study concerns the question how adolescents lose the ability to experience pleasure and may gain it back again (

  1. Different Aspects of the Neural Response to Socio-Emotional Events Are Related to Instability and Inertia of Emotional Experience in Daily Life: An fMRI-ESM Study

    Provenzano, J., Bastiaansen, J. A., Verduyn, P., Oldehinkel, A. J., Fossati, P. & Kuppens, P. 11-Dec-2018 In : Frontiers in Human Neuroscience. 12, 10 p., 501

    Research output: Contribution to journalArticle

  2. Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (vol 50, pg 1412, 2018)

    Million Vet Program Dec-2018 In : Nature Genetics. 50, 12, p. 1755 1 p.

    Research output: Contribution to journalArticle

  3. Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

    Million Veteran Program 14-Nov-2018 In : Nature Genetics. 1 p.

    Research output: Contribution to journalArticle

  4. Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

    Lifelines Cohort Study, Charge Lipids Working Grp, van Leeuwen, E. M., Huffman, J. E., Bis, J. C., Isaacs, A., Mulder, M., Sabo, A., Smith, A. V., Demissie, S., Manichaikul, A., Brody, J. A., Feitosa, M. F., Duan, Q., Schraut, K. E., Navarro, P., van Vliet-Ostaptchouk, J. V., Zhu, G., Mbarek, H., Trompet, S., Verweij, N., Lyytikainen, L-P., Deelen, J., Nolte, I. M., van der Laan, S. W., Davies, G., Vermeij-Verdoold, A. J. M., van Oosterhout, A. A. L. J., Vergeer-Drop, J. M., Arking, D. E., Trochet, H., Scotland, G., Medina-Gomez, C., Rivadeneira, F., Uitterlinden, A. G., Dehghan, A., Franco, O. H., Sijbrands, E. J., White, C. C., Mychaleckyj, J. C., Peloso, G. M. & Swertz, M. A. 2015 In : Npj aging and mechanisms of disease. 1, 9 p., 15011

    Research output: Contribution to journalArticle

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  1. Waarom worden jonge mensen depressief?

    Oldehinkel, T. (Speaker)

    Activity: ProfessionalTalk or presentation

  2. Development MOOC 'Young people and their mental health'

    Oldehinkel, T. (Other), Maaike Meurs (Other), Spits, T. (Other)

    Activity: PopularOther

  3. Development MOOC 'Jongeren en hun psychische gezondheid'

    Oldehinkel, T. (Other), Maaike Meurs (Other), Spits, T. (Other)

    Activity: PopularOther

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Press / Media
  1. Depressie bij jongeren

    Tineke Oldehinkel & Robert Schoevers


    2 media contribution

    Press/Media: Expert Comment

  2. Free online course about mental health for young people

    Tineke Oldehinkel & Maaike Meurs


    1 media contribution

    Press/Media: Public Engagement Activities

  3. Elf jaar oud en risico op een depressie

    Tineke Oldehinkel, Chaïm la Roi, Jan Dijkstra, René Veenstra & Tina Kretschmer


    1 item of media coverage

    Press/Media: Research

View all (15) »

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