Postal address:
A Deusinglaan
Gebouw 3211, ruimte 0474
Phone: +31 50 363 3305Fax: +31 50 363 6908

Research interests

Applied Research Activities

Structure-based drug design in human diseases

Basic Research Activities

Structural, biochemical and molecular biology investigation of malarial pathways:

Carbon metabolism in P falciparum

Vitamin biosynthesis in P. falciparum

Method Developments

Crystal identification for structural biology

Biological imaging on free-electron lasers 

  1. Afatinib in Osimertinib-Resistant EGFR ex19del / T790M / P794L mutated Non-Small Cell Lung Cancer

    van Kempen, L. C., Wang, H., Aguirre, M. L., Spatz, A., Kasymjanova, G., Vilacha, J. F., Groves, M. R., Agulnik, J. & Small, D. 25-Apr-2018 In : Journal of Thoracic Oncology.

    Research output: Contribution to journalArticle

  2. Isolation and molecular characterization of novel glucarpidases: Enzymes to improve the antibody directed enzyme pro-drug therapy for cancer treatment

    Rashidi, F. B., AlQhatani, A. D., Bashraheel, S. S., Shaabani, S., Groves, M. R., Dömling, A. & Goda, S. K. 26-Apr-2018 In : PLoS ONE. 13, 4, 22 p., e0196254

    Research output: Contribution to journalArticle

  3. Oligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro

    Lunev, S., Butzloff, S., Romero, A. R., Linzke, M., Batista, F. A., Meissner, K. A., Müller, I. B., Adawy, A., Wrenger, C. & Groves, M. R. 25-Apr-2018 In : PLoS ONE. 13, 4, p. e0195011

    Research output: Contribution to journalArticle

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  1. Pharmacy Day 2018

    Salvati, A. (Organiser), Dolga, A. (Organiser), Groves, M. (Organiser), Mathwig, K. (Organiser), Horvatovich, P. (Organiser), Quax, W. (Organiser), Lexmond, A. (Organiser), Nieuwenhuis-Dempsey, G. (Organiser)

    Activity: ScientificOrganising an event

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