Replication Data for: Cognitive-behavior therapy for children and adolescents with anxiety disorders: a meta-analysis of secondary outcomes

Kreuze, L. (Creator), Pijnenborg, M. (Creator), de Jonge, Y. (Creator), Nauta, M. (Creator), University of Groningen, 2-Nov-2018



Anxiety-focused cognitive-behavioral therapy (CBT) effectively reduces anxiety in children and adolescents. An important remaining question is to what extent anxiety-focused CBT also affects broader outcome domains. Additionally, it remains unclear whether parental involvement in treatment may have impact on domains other than anxiety. A meta-analysis (nstudies=42, nparticipants=3239) of the effects of CBT and the moderating role of parental involvement was conducted on the following major secondary outcomes: depressive symptoms, externalizing behaviors, general functioning, and social competence. Randomized controlled trials were included when having a waitlist or active control condition, a youth sample (aged<19) with a primary anxiety disorder diagnosis receiving anxiety-focused CBT and reported secondary outcomes. Controlled effect sizes (Cohen’s d) were calculated employing random effect models. CBT had a large effect on general functioning (-1.25[-1.59;0.90], nstudies=17), a small to moderate effect on depressive symptoms (-0.31[-0.41;-0.22], nstudies=31) and a small effect on externalizing behaviors (-0.23[-0.38;-0.09], nstudies=12) from pre-to post-treatment. Effects remained or even further improved at follow-up. Social competence only improved at follow-up (nstudies = 6). Concluding, anxiety-focused CBT has a positive effect on broader outcome domains than just anxiety. Higher parental involvement seemed to have beneficial effects at follow-up, with improvements in general functioning and comorbid symptoms. (2018-10-23)
Date made available2-Nov-2018
PublisherUniversity of Groningen
Access to the dataset Open

    Keywords on Datasets

  • CBT, Anxiety disorder, Children, Meta-analysis, Secondary outcomes, Depressive symptoms, Externalizing behaviors, General functioning, Social competence
Related Publications
  1. Cognitive-behavior therapy for children and adolescents with anxiety disorders: A meta-analysis of secondary outcomes

    Kreuze, L. J., Pijnenborg, G. H. M., de Jonge, Y. B. & Nauta, M. H., Dec-2018, In : Journal of Anxiety Disorders. 60, p. 43-57 15 p.

    Research output: Contribution to journalArticleAcademicpeer-review

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ID: 71892762