Dataset: TGF-Beta activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation
Ng-Blichfeldt, J. (Creator), Jong ,de, T. (Creator), Kortekaas, R. (Creator), Wu, S. (Creator), Lindner, M. (Creator), Guryev, V. (Creator), Hiemstra, P. S. (Creator), Stolk, J. (Creator), Konigshoff, M. (Creator), Gosens, R. (Creator), University of Groningen, 19-Feb-2019
Complete processed RNA Sequencing dataset containing all raw read counts per sample. Samples were primary human lung fibroblasts obtained from 4 donors, each treated with 1 of 4 conditions (Vehicle, CHIR99021, TGFβ, CHIR99021 + TGFβ) for 24 hours prior to RNA isolation and processing for RNA sequencing (see text for details).
|Date made available||19-Feb-2019|
|Publisher||University of Groningen|
|Access to the dataset||Open|
- Health, TGF-Beta-induced myofibroblasts, human lung fibroblast, in vitro, epithelial repair, COPD, IPF, CHIR99021, chronic inflammatory diseases
Keywords on Datasets
TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formationNg-Blichfeldt, J-P., de Jong, T., Kortekaas, R. K., Wu, X., Lindner, M., Guryev, V., Hiemstra, P. S., Stolk, J., Koenigshoff, M. & Gosens, R., Jul-2019, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 317, 1, p. L14-L28 15 p.
Research output: Contribution to journal › Article › Academic › peer-review