Dataset

Dataset: TGF-Beta activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation

Ng-Blichfeldt, J. (Creator), Jong, de, T. (Creator), Kortekaas, R. (Creator), Wu, S. (Creator), Lindner, M. (Creator), Guryev, V. (Creator), Hiemstra, P. S. (Creator), Stolk, J. (Creator), Konigshoff, M. (Creator), Gosens, R. (Creator), University of Groningen, 19-Feb-2019

Dataset

Description

1602_Gosens_RNAseq.expression.genelevel.v75.htseq.txt
Complete processed RNA Sequencing dataset containing all raw read counts per sample. Samples were primary human lung fibroblasts obtained from 4 donors, each treated with 1 of 4 conditions (Vehicle, CHIR99021, TGFβ, CHIR99021 + TGFβ) for 24 hours prior to RNA isolation and processing for RNA sequencing (see text for details).
Date made available19-Feb-2019
PublisherUniversity of Groningen
Access to the dataset Open
Contact researchdata@rug.nl

    Keywords on Datasets

  • Health, TGF-Beta-induced myofibroblasts, human lung fibroblast, in vitro, epithelial repair, COPD, IPF, CHIR99021, chronic inflammatory diseases
Related Publications
  1. TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation

    Ng-Blichfeldt, J-P., de Jong, T., Kortekaas, R. K., Wu, X., Lindner, M., Guryev, V., Hiemstra, P. S., Stolk, J., Koenigshoff, M. & Gosens, R., Jul-2019, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 317, 1, p. L14-L28 15 p.

    Research output: Contribution to journalArticleAcademicpeer-review

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ID: 94904244