Dataset

Dataset: TGF-Beta activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation

Ng-Blichfeldt, J. (Creator), Jong ,de, T. (Creator), Kortekaas, R. (Creator), Wu, S. (Creator), Lindner, M. (Creator), Guryev, V. (Creator), Hiemstra, P. S. (Creator), Stolk, J. (Creator), Konigshoff, M. (Creator), Gosens, R. (Creator), University of Groningen, 19-Feb-2019

Dataset

Description

1602_Gosens_RNAseq.expression.genelevel.v75.htseq.txt
Complete processed RNA Sequencing dataset containing all raw read counts per sample. Samples were primary human lung fibroblasts obtained from 4 donors, each treated with 1 of 4 conditions (Vehicle, CHIR99021, TGFβ, CHIR99021 + TGFβ) for 24 hours prior to RNA isolation and processing for RNA sequencing (see text for details).
Date made available19-Feb-2019
PublisherUniversity of Groningen
Access to the dataset Open
Contact researchdata@rug.nl

    Keywords on Datasets

  • Health, TGF-Beta-induced myofibroblasts, human lung fibroblast, in vitro, epithelial repair, COPD, IPF, CHIR99021, chronic inflammatory diseases
Related Publications
  1. TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation

    Ng-Blichfeldt, J-P., de Jong, T., Kortekaas, R. K., Wu, X., Lindner, M., Guryev, V., Hiemstra, P. S., Stolk, J., Koenigshoff, M. & Gosens, R., Jul-2019, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 317, 1, p. L14-L28 15 p.

    Research output: Contribution to journalArticleAcademicpeer-review

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ID: 94904244