Dataset: Meta-analysis results of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

Küpers, L. (Creator), University of Groningen, 12-Dec-2018


  • Leanne Küpers (Creator)


Birthweight is associated with health outcomes across the life course, DNA methylation may be an underlying mechanism. In this meta-analysis of epigenome-wide association studies of 8,825 neonates from 24 birth cohorts in the Pregnancy And Childhood Epigenetics Consortium, DNA methylation in neonatal blood is associated with birthweight at 914 sites, with a difference in birthweight ranging from -183 to 178 grams per 10% increase in methylation (PBonferroni<1.06x10-7).
Date made available12-Dec-2018
PublisherUniversity of Groningen
Access to the dataset Open

    Keywords on Datasets

  • DNA methylation, EWAS, epigenome-wide association study, Meta-analysis, epigenetic epidemiology, birthweight, birth weight, DOHAD, PACE consortium, Pregnancy and Childhood Epigenetics

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ID: 79519002