Press/Media items

New method measures single molecules from nanoliter of blood in real time

Press/Media: Public Engagement ActivitiesPopular

10/10/2018

University of Groningen scientists, led by Associate Professor of Chemical Biology Giovanni Maglia, have designed a nanopore system that is capable of measuring different metabolites simultaneously in a variety of biological fluids, all in a matter of seconds. The electrical output signal is easily integrated into electronic devices for home diagnostics. The results were published in Nature Communications.

Measuring many metabolites or drugs in the body is complicated and time consuming, and real-time monitoring is not usually possible. The ionic currents that pass through individual nanopores are emerging as a promising alternative to standard biochemical analysis. Nanopores are already integrated into portable devices to determine DNA sequences. "But it is basically impossible to use these nanopores to specifically identify small molecules in a complex biological sample," says Maglia.

References

Related Publications
  1. Direct electrical quantification of glucose and asparagine from bodily fluids using nanopores

    Galenkamp, N. S., Soskine, M., Hermans, J., Wloka, C. & Maglia, G., 5-Oct-2018, In : Nature Communications. 9, 1, 8 p., 4085.

    Research output: Contribution to journalArticleAcademicpeer-review

View all (1) »

ID: 67334827