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PIL on Tuesday, February 14th

When:Tu 14-02-2017 12:00 - 13:00
Where:Keuningzaal 3214-0081
Dear colleagues and students,
The sixth PIL (Pharmacy Interdepartmental Lecture) of year 2016/2017 will be held on Tuesday, February 14th at 12 midday in 3214-0081 with a lunch afterwards in the catering area opposite the Keuningzaal.
The PIL will be given by Jan Jacob Schuringa from the department of Hematology of the UMCG. The titel of his presentation is:
From identification towards targeting and eradication of human leukemic stem cells
The aims of the Schuringa lab (Experimental Hematology) are to obtain detailed knowledge on mechanisms that determine hematopoietic stem cell self-renewal and differentiation, with the ultimate goal of acquiring deeper insights into the development of human leukemias. The latest findings of the lab will be discussed: 1) the generation of humanized niche xenograft models in which a human niche is reconstructed in NSG mice to faithfully model human leukemias (Antonelli et al, Blood 2016; Sontakke et al, Leukemia 2016); 2) the identification of a novel non-canonical PRC1.1 epigenetic regulatory complex that keeps loci in an active conformation (van den Boom et al, Cell Reports 2016); and 3) the identification of AML-specific plasma membrane proteins that provide insight into clonal heterogeneity in AML and provide tools for prospective isolation  of (epi)genetically distinct subclones within individual patients (in progress).
The dates and locations of the PIL meetings in 2017 are as follows:
Tuesday, February 14th: 3214-0081  -  Jan Jacob Schuringa
Tuesday, March 14th: 3214-0081  -  Hidde Haisma
Tuesday, April 11th: 3214-0081 -  Ellen Nollen
Tuesday, May 16th: room to be announced - Dr. Julien Beyrath (not May 9th as previously indicated)
Tuesday, June 20th: Pharmacy Day
You are all more than welcome to attend the PIL meetings. The PIL committee hopes that you will come in great numbers.
Best regards, also on behalf of the new PIL committee: Wim Quax, Matthew Groves, Amalia Dolga, Klaus Mathwig, Peter Horvatovich & Anna Salvati.