MCB Seminar - Prof. Carlos Camacho - University of Pittsburgh, USA
|When:||We 04-05-2016 15:00 - 16:00|
The Medicinal Chemistry & Bioanalysis (MCB) Program GUIDE – Graduate School for Drug Exploration
Prof. Carlos Camacho
Department of Computational Biology
School of Medicine, University of Pittsburgh USA
What does it take to modulate regulatory proteins?
A key challenge modulating regulatory proteins has been to understand their intrinsic flexibility. In this presentation, the key role that flexibility plays in regulation will be explained. As an example, it will be discussed in detail how the intrinsic flexibility of PD‐1 is modulated by its cognate ligands PD‐L1 and PD‐L2.