During the meeting, all aspects of mechanisms of biofilm formation, their prevention and materials aspects will be discussed from a multidisciplinary perspective without any boundaries. The theme this year centers around the question of how to kill bacteria in a biofilm-mode of growth from biofilm-top to bottom in order to prevent infection recurrence. Moreover, the troubling challenge on how best to establish bacterial death will be addressed. Should we make better use of existing antibiotics, or develop more coatings or rely more nanotechnology? Will anything translate clinically? Or must we turn to a more desperate, audacious practices with animal pre-clinical and human clinical studies, avoiding more and more stringent regulations, as did past giants of biomedical engineering, like WJ Kolff pioneering replacement of natural body parts with implanted machines.