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Informatie over BSc Farmacie/ Pharmacy
Hieronder staan het programma en de vakomschrijvingen van BSc Farmacie/ Pharmacy Klik op de naam van een vak in een schema om naar de omschrijving te gaan.
| » Jaar 1 (hoofdprogramma) | |||||||
| Periode | Type | Code | Naam | Taal | ECTS | Uren | |
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| hele jaar | verplicht | WBFA001-05 | Academic Research & Communication Skills 1 | Engels | 5 | variabel | |
| semester I a | verplicht | WBFA004-03 | Genetics | Engels | 3 | ||
| verplicht | WBFA006-04 | Molecular Biology of the Cell 1 | Engels | 4 | |||
| verplicht | WBFA007-04 | Molecular Biology of the Cell 2 | Engels | 4 | |||
| verplicht | WBFA010-03 | The Cell, a Practical Approach | Engels | 3 | |||
| semester I b | verplicht | WBMA021-05 | Mathematics and Statistics | Engels | 5 | ||
| verplicht | WBFA017-05 | Pharmaceutical Technology and Biopharmacy 1 | Engels | 5 | |||
| verplicht | WBFA020-05 | Physiology and Pharmacology | Engels | 5 | variabel | ||
| semester II a | verplicht | WBFA022-03 | Human Physiology | Engels | 3 | ||
| verplicht | WBCH025-05 | Molecules and Reactivity | Engels | 5 | |||
| verplicht | WBFA024-05 | Pathology | Engels | 5 | |||
| semester II b | verplicht | WBFA034-03 | Global Health and Pharmacotherapy | Engels | 3 | 11 | |
| verplicht | WBFA035-05 | Pharmaceutical Analysis A | Engels | 5 | |||
| verplicht | WBFA036-05 | Receptor Pharmacology | Engels | 5 | |||
| » Jaar 2 (hoofdprogramma) | |||||||
| Periode | Type | Code | Naam | Taal | ECTS | Uren | |
| semester I a | verplicht | WBFA003-04 | Academic Research and Communication Skills 2 | Engels | 4 | ||
| verplicht | WBFA005-06 | Instrumental Analysis | Engels | 6 | |||
| verplicht | WBFA008-05 | Organic and Biosynthesis | Engels | 5 | |||
| semester I b | verplicht | WBFA011-05 | Biostatistics | Engels | 5 | ||
| verplicht | WBFA016-05 | Metabolism and Toxicology | Engels | 5 | |||
| verplicht | WBFA018-05 | Pharmacokinetics | Engels | 5 | |||
| semester II a | verplicht | WBFA025-05 | Pharmaceutical Microbiology | Engels | 5 | ||
| verplicht | WBFA028-05 | Pharmacoepidemiology | Engels | 5 | |||
| verplicht | WBFA030-00 | Safe Microbiological Techniques | Engels | ||||
| semester II b | verplicht | WBFA032-05 | Bioanalysis | Engels | 5 | ||
| verplicht | WBFA015-05 | Immunopharmacology | Engels | 5 | |||
| » Jaar 2 (major Medical Pharmaceutical Sciences) | |||||||
| Periode | Type | Code | Naam | Taal | ECTS | Uren | |
| semester II a | keuze | WBFA037-05 | Collected Medicine Groups | Engels | 5 | ||
| keuze | WBFA026-05 | Pharmaceutical Technology and Biopharmacy 2 | Engels | 5 | |||
| semester II b | keuze | WBFA033-05 | Central Nervous System, drugs for the | Engels | 5 | ||
| » Jaar 2 (major Pharmacy) | |||||||
| Periode | Type | Code | Naam | Taal | ECTS | Uren | |
| semester II a | verplicht | WBFA026-05 | Pharmaceutical Technology and Biopharmacy 2 | Engels | 5 | ||
| semester II b | verplicht | WBFA033-05 | Central Nervous System, drugs for the | Engels | 5 | ||
| » Jaar 3 (hoofdprogramma) | |||||||
| Periode | Type | Code | Naam | Taal | ECTS | Uren | |
| semester II | verplicht | WBFA042-01 | Academic Research and Communication Skills 3 | Engels | 1 | variabel | |
| verplicht | WBFA902-14 | Bachelor Research Project | Engels | 14 | |||
| semester II a | keuzegroep A | WBFA050-05 | From clinical trials to big data research | Engels | 5 | ||
| keuzegroep A | WBFA047-05 | Introduction to PharmacoEconomics | Engels | 5 | |||
| keuzegroep A | WBFA046-05 | Patient Perspectives in Pharmacy | Engels | 5 | |||
| keuzegroep B | WBFA043-05 | Advanced Bioanalysis | Engels | 5 | |||
| keuzegroep B | WBFA044-10 | Proteins for Biopharmaceuticals & Drug Discovery | Engels | 10 | |||
| semester II b | keuzegroep C | WBFA051-05 | Advanced Human Disease Model Technologies | Engels | 5 | ||
| keuzegroep C | WBFA052-05 | Patient cases in laboratory medicine | Engels | 5 | |||
| keuzegroep C | WBFA048-05 | Pharmacology of Chronic Diseases and Ageing | Engels | 5 | variabel | ||
| keuzegroep D | WBFA045-10 | Advanced Pharmaceutical Technology and Therapeutics | Engels | 10 | |||
| keuzegroep D | WBFA049-05 | Drug Toxicology and Translational Technology | Engels | 5 | |||
| » Jaar 3 (major Medical Pharmaceutical Sciences) | |||||||
| Periode | Type | Code | Naam | Taal | ECTS | Uren | |
| semester I b | keuze | WBCH014-05 | Organische Chemie Practicum | Engels | 5 | ||
| keuze | WBFA021-05 | Thermodynamica | Nederlands | 5 | |||
| » Jaar 3 (Minor Pharmacy) | |||||||
| Periode | Type | Code | Naam | Taal | ECTS | Uren | |
| semester I | verplicht | WBFA019-05 | Pharmacology practical | Engels | 5 | ||
| semester I a | verplicht | WBFA038-05 | Medicinal Chemistry and Biophysics | Engels | 5 | ||
| verplicht | WBFA039-05 | MG: Endocrine System and Digestive and Respiratory Tract | Engels | 5 | |||
| semester I b | verplicht | WBFA040-05 | MG: Circulatory Tract | Engels | 5 | ||
| verplicht | WBFA041-05 | MG: Infectious diseases and Oncology | Engels | 5 | |||
| verplicht | WBCH014-05 | Organische Chemie Practicum | Engels | 5 | |||
| 1 | Academic Research & Communication Skills 1 | WBFA001-05 | |||||||||||||||||||||||||||
| - To develop academic research and communication skills, namely how to a. formulate a research question b. find relevant scientific papers (introduction PubMed, WoS) c. critically read and comment on scientific papers d. write scientifically (incl. poster preparation) e. present research orally - To learn about research codes of conduct with respect to: a. Principles underlying the Dutch Code of Conduct for Academic Practice (Nederlandse Gedragscode Wetenschapsbeoefening) b. Academic fraud, including plagiarism, fabrication of information or lab results, and cheating on exams - To become familiar with research in the Groningen Research Institute of Pharmacy | |||||||||||||||||||||||||||||
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| 2 | Academic Research and Communication Skills 2 | WBFA003-04 | |||||||||||||||||||||||||||
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| 3 | Academic Research and Communication Skills 3 | WBFA042-01 | |||||||||||||||||||||||||||
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| 4 | Advanced Bioanalysis | WBFA043-05 | |||||||||||||||||||||||||||
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| 5 | Advanced Human Disease Model Technologies | WBFA051-05 | |||||||||||||||||||||||||||
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| 6 | Advanced Pharmaceutical Technology and Therapeutics | WBFA045-10 | |||||||||||||||||||||||||||
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| 7 | Bachelor Research Project | WBFA902-14 | |||||||||||||||||||||||||||
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| 8 | Bioanalysis | WBFA032-05 | |||||||||||||||||||||||||||
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| 9 | Biostatistics | WBFA011-05 | |||||||||||||||||||||||||||
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| 10 | Central Nervous System, drugs for the | WBFA033-05 | |||||||||||||||||||||||||||
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| 11 | Collected Medicine Groups | WBFA037-05 | |||||||||||||||||||||||||||
| The following topics are covered in the course Collected Medicine Groups: Physiology and pathology of major organ systems in the human body, including the respiratory tract, the cardiovascular system, central nervous system (CNS) and endocrine system Molecular pharmacology of widely used drugs for the treatment of respiratory diseases (e.g. Asthma and COPD), of diseases affecting the CNS (Parkinson and Alzheimer Disease), of cardiovascular diseases and Diabetes Mellitus | |||||||||||||||||||||||||||||
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| terug naar boven | |||||||||||||||||||||||||||||
| 12 | Drug Toxicology and Translational Technology | WBFA049-05 | |||||||||||||||||||||||||||
| In this course, we will build on the basic knowledge of toxicology that students have acquired in the second year course on ‘Metabolism and Toxicology’. Interactions of drugs with various systems in the human body will be discussed, with particular focus on toxicological effects drugs may have in these systems. With the arrival of advanced strategies for drug delivery, evaluation of changes in drug toxicity profiles and drug safety are essential. As such, novel and traditional toxicity testing methods and models will be discussed and compared. | |||||||||||||||||||||||||||||
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| 13 | From clinical trials to big data research | WBFA050-05 | |||||||||||||||||||||||||||
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| terug naar boven | |||||||||||||||||||||||||||||
| 14 | Genetics | WBFA004-03 | |||||||||||||||||||||||||||
| The course Genetics is a follow-up and assumes prior knowledge and skills of the courses Molecular Biology of the Cell 1 and 2. Genetics connects with the learning outcomes a,b,f and j of the Pharmacy bachelor programme. This course deals with the following subjects: Mendel genetics; Inheritance patterns; Making linkage maps; Genome and population evolution; Population genetics; Pharmacogenetics; Biotechnology: different techniques to investigate gene expression and the function of genes, the production of new drugs, gene therapy. The course unit prepares for and provides skills usable in the course units Infections and Tumours, Clinical Chemistry and Pathophysiology, Innovative Therapeutics and Pharmacotherapy. | |||||||||||||||||||||||||||||
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| terug naar boven | |||||||||||||||||||||||||||||
| 15 | Global Health and Pharmacotherapy | WBFA034-03 | |||||||||||||||||||||||||||
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| 16 | Human Physiology | WBFA022-03 | |||||||||||||||||||||||||||
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| 17 | Immunopharmacology | WBFA015-05 | |||||||||||||||||||||||||||
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| terug naar boven | |||||||||||||||||||||||||||||
| 18 | Instrumental Analysis | WBFA005-06 | |||||||||||||||||||||||||||
| In this course the following subjects are addressed: Theory: • the principles of a number of instrumental analytical methods used in pharmaceutical analysis, clinical chemistry, toxicology, bioanalytical, medicinal chemistry, pharmacology and pharmaceutical technology; • the fundamental physicochemical principles on which the measurement is based and the construction of the instrument, insight into the possibilities and limitations of the method; • UV-VIS absorbance and fluorescence spectroscopy. Electrochemical principles: redox reactions, the electrochemical cell & electrode potentials; electrochemical analytical methods: voltammetry, and (bi)amperometric endpoint detection in titrations. • Separation methods: fundamentals of chromatography, focused on high-performance liquid chromatography (HPLC). Lab: • the emphasis is on learning to use the equipment, understanding the underlying theory; • Bi-Amperomic titration using electrochemical endpoint determination. • Voltammetric titration of drug preparations • UV-Vis spectrophotometry: determination of pharmaceuticals, • HPLC: determination of drug preparations and determining chromatographic analysis variables • critically analysing and assessing measurements and results. | |||||||||||||||||||||||||||||
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| 19 | Introduction to PharmacoEconomics | WBFA047-05 | |||||||||||||||||||||||||||
| An introduction to Pharmacoeconomics at bachelor level, with a focus on trial based economic evaluation (cost-effectiveness analysis) and budget impact analysis. In comparison to the master course PharmacoEconomics, this course focuses on the use of trial data, and gathering empirical information about cost-effectiveness, as well as analyzing these data. Simulation models are not discussed in this course. Both courses introduce the concept of cost-effectiveness, the cost-effectiveness plane and interpretation of findings, but the mastercourse goes more into depth. The course consists of lectures, student presentations and group work (3 assignments). This course is part of the 3rd year electives within the combined set of courses that also contains the courses: From clinical trials to big data research and Innovative Patient Care in Pharmacy. (Keuzegroep A). As such, students are expected to be in their 3rd year of study, and to have basic knowledge of statistics and SPSS, having passed mathematics and statistics (year 1). | |||||||||||||||||||||||||||||
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| 20 | Mathematics and Statistics | WBMA021-05 | |||||||||||||||||||||||||||
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| 21 | Medicinal Chemistry and Biophysics | WBFA038-05 | |||||||||||||||||||||||||||
| 1. This course unit explains how molecular shape controls biological function. Students are provided with tools with which to describe the relationships between the structure of the pharmaceutical and its biological activity. 2. The process of the binding of pharmaceuticals to DNA, receptors and enzymes will be explained by paying attention to hydrophobic, electronic and steric (shape) parameters. 3. The most commonly used spectroscopic (MS, IR, NMR) and biophysical (ITC, DSF) techniques used to characterize organic molecules will be explained, with a focus on the underlying principles and the interpretation of the data. 4. Finally, the importance of structure–activity relationship (SAR) analysis in drug development will be explained using modern examples. | |||||||||||||||||||||||||||||
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| 22 | Metabolism and Toxicology | WBFA016-05 | |||||||||||||||||||||||||||
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| 23 | MG: Circulatory Tract | WBFA040-05 | |||||||||||||||||||||||||||
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| 24 | MG: Endocrine System and Digestive and Respiratory Tract | WBFA039-05 | |||||||||||||||||||||||||||
| In the course MG: Endocrine System and Digestive and Respiratory Tract, the following topics are discussed: Respiratory tract: bronchodilators, anti-inflammatories, anti-allergics, decongestants, cough medicines; Digestive tract: stomach / esophagus: anti-ulcer drugs, prokinetics, anti-emetics; intestines: antispasmodics, anti-diarrheal agents, laxatives, anti-inflammatory agents; Skin: keratolytics, keratoplastics, anti-inflammatory agents, anti-allergics. Endocrine system: - Carbohydrate, protein and fat metabolism: thyroid hormones, antithyroid drugs, glucocorticosteroids, pancreatic hormones, growth hormone. - Immune system: glucocorticosteroids. - Water and mineral balance: ADH, mineralocorticosteroids, calcitriol, calcitonin. - Growth: growth hormone, thyroid hormones, sex hormones. - Reproduction: estrogens, progestins, anti-estrogens, antiprogestants, contraceptives, oxytocin, prolactin, androgens, anabolic steroids, anti-androgens. | |||||||||||||||||||||||||||||
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| 25 | MG: Infectious diseases and Oncology | WBFA041-05 | |||||||||||||||||||||||||||
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| 26 | Molecular Biology of the Cell 1 | WBFA006-04 | |||||||||||||||||||||||||||
| In the course the following topics will be addressed: the origin of life; the important building blocks of living cells; the evolution of life; cytology (pro- and eukaryotic organisms); cell walls and their components; biomembranes; cell organelles; genetics: DNA, RNA, chromosomes; replication of DNA; division of nucleus; division of cells; virusses; metabolism; physiology of the cell; enzymology; carbohydrate metabolism; citric acid cycle; lipid metabolism, respiratory chain, photosynthesis; protein structure; protein synthesis, enzyme kinetics; receptors and signal transduction; developmental biology; cell growth and cell differentiation; hormones; gene regulation; molecular biology techniques: electrophoresis, chromatography; polymerase chain reaction; in-vitro cell culturing; biotechnology for pharmacy; biologicals; monoclonal antibodies; interferones; interleukines; genomics en proteomics. (Ch. 1-9 Alberts et al.) | |||||||||||||||||||||||||||||
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| 27 | Molecular Biology of the Cell 2 | WBFA007-04 | |||||||||||||||||||||||||||
| The MBOC 2 course is the follow up to the MBOC 1 course. The joint topics dealt with and the joint learning outcomes are described in here. In the course the following topics will be addressed: the origin of life; the important building blocks of living cells; the evolution of life; cytology (pro- and eukaryotic organisms); cell walls and their components; biomembranes; cell organelles; genetics: DNA, RNA, chromosomes; replication of DNA; division of nucleus; division of cells; virusses; metabolism; physiology of the cell; enzymology; carbohydrate metabolism; citric acid cycle; lipid metabolism, respiratory chain, photosynthesis; protein structure; protein synthesis, enzyme kinetics; receptors and signaltransduction; developmental biology; cell growth and cell differentiation; hormones; gene regulation; molecular biology techniques: electrophoresis, chromatography; polymerase chain reaction; in vitro cell culturing; biotechnology for pharmacy; biologicals; monoclonal antibodies; interferons; interleukines; genomics en proteomics. (Ch. 10-18 Alberts et al.) | |||||||||||||||||||||||||||||
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| 28 | Molecules and Reactivity | WBCH025-05 | |||||||||||||||||||||||||||
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| 29 | Organic and Biosynthesis | WBFA008-05 | |||||||||||||||||||||||||||
In deze cursus komen de volgende onderwerpen aan bod:
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| 30 | Organische Chemie Practicum | WBCH014-05 | |||||||||||||||||||||||||||
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| 31 | Pathology | WBFA024-05 | |||||||||||||||||||||||||||
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| 32 | Patient cases in laboratory medicine | WBFA052-05 | |||||||||||||||||||||||||||
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| 33 | Patient Perspectives in Pharmacy | WBFA046-05 | |||||||||||||||||||||||||||
| Introduction in topics of innovative practices in the pharmacy, with a focus on practices that aim to improve pharmaceutical patient care. This subject is related to the changes in the profession of the pharmacy. Increasingly, pharmacists support patients in their medication use. In a world with an increasing number of patients with complex problems this calls for innovative practices, including e-health solutions. In this course, we will introduce the challenges patients face to include medication use in their daily life. Moreover, we will introduce innovative concepts that pharmacists can use to improve patient care and support patients in good medication use. From a set of innovations, students will choose one and analyse this innovation from different angles: what does this innovation mean from the patient perspective? What does this innovation mean from the pharmacist perspective? And from other pharmacy staff members? What does it mean from a societal perspective? What are challenges that can be faced? What are the costs? What would be good outcome measures to evaluate the impact of innovations? Students will individually write a report in which they present their analyses of the innovation from these different angles. | |||||||||||||||||||||||||||||
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| 34 | Pharmaceutical Analysis A | WBFA035-05 | |||||||||||||||||||||||||||
| In deze cursus komen de volgende onderwerpen aan bod: Theorie:
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| 35 | Pharmaceutical Microbiology | WBFA025-05 | |||||||||||||||||||||||||||
| In deze cursus komen de volgende onderwerpen aan bod: a) Theorie: de prokaryote cel: de bouw en functie van celbestanddelen, verschillen met de eukaryote cel; groei en voedingseisen van micro-organismen: groeikinetiek, nutriënten en andere milieuparameters; energietransductie en metabolische diversiteit bij prokaryoten: glycolyse, de citroenzuurcyclus, elektronentransportketens, de protondrijvende kracht, gisting, anaerobe ademhaling, chemolithotrofie, de vorming van precursors voor biosynthese; taxonomische diversiteit bij micro-organismen: soort- en stambegrip, domeinen (Bacteria, Archaea, Eukarya); antibiotica: werkingsmechanisme, toepassingen, resistentie; sterilisatie en desinfectie: afstervingskinetiek, farmaceutische sterilisatiemethoden met hun toepassingen; klinische en farmaceutische microbiologie: de normale flora van het menselijk lichaam, interactie met pathogenen, de toxiciteit van toxinen, isolatie en identificatie van micro-organismen uit klinische monsters, biologische veiligheid, kwaliteitsbeheersing van farmaceutische preparaten, het gebruik van bacteriën voor analytische doeleinden; biofilms: het ontstaan van biofilms, pathogenen in biofilms, quorum sensing, antibioticatolerantie. b) Practicum: diverse technieken om contaminatievrij en onder VMT-condities te werken; fasecontrast-microscopie; sterilisatie d.m.v. UV-straling; isolatie van micro-organismen, kweken van bacteriecultures in batch, ophopingscultures, het uitstrijken op agarplaten; het bepalen van de groeisnelheid en verdubbelingstijd in een batch-cultuur; identificatie van bacteriën m.b.v. genetische technieken; antibiotica: cross-streak, gehaltebepaling, resistentieoverdracht d.m.v. conjugatie; onderzoek van de microbiologische zuiverheid van farmaceutische preparaten en grondstoffen volgens de farmacopee. | |||||||||||||||||||||||||||||
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| 36 | Pharmaceutical Technology and Biopharmacy 1 | WBFA017-05 | |||||||||||||||||||||||||||
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| 37 | Pharmaceutical Technology and Biopharmacy 2 | WBFA026-05 | |||||||||||||||||||||||||||
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| 38 | Pharmacoepidemiology | WBFA028-05 | |||||||||||||||||||||||||||
| In deze cursus komen de volgende onderwerpen aan bod:de plaats van de farmaco-epidemiologie binnen de farmacie; frequentie- en risicomaten; onderzoeksobjecten: etiologie, diagnostiek, prognostiek, interventie; spontanerapportagesystemen, bronnen, databases, record linkage; onderzoeksopzet: cohort, case-control, dwarsdoorsnede; typen van bias: informatiebias, selectiebias, confounding; causaliteit; precisie en validiteit; systematische fouten en toevalsfouten; farmaco-economie; systematische review en meta-analyse; het lezen en beoordelen van een farmaco-epidemiologisch artikel. De cursus wordt als pilot in het Engels gegeven. | |||||||||||||||||||||||||||||
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| 39 | Pharmacokinetics | WBFA018-05 | |||||||||||||||||||||||||||
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| 40 | Pharmacology of Chronic Diseases and Ageing | WBFA048-05 | |||||||||||||||||||||||||||
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| 41 | Pharmacology practical | WBFA019-05 | |||||||||||||||||||||||||||
| Kennismaking met farmacologische methoden en technieken tot vaststelling van de werking van geneesmiddelen in het lichaam. Getracht wordt, d.m.v. door de studenten zelf geïnitieerde onderzoeksprotocollen, het werkingsprofiel van 3 onbekende farmaca te achterhalen aan de hand van farmacologische referentiestoffen en gebruikmakend van verschillende farmacologische opstellingen. Onbekende geneesmiddelen worden in vergelijking met bekende agonisten en antagonisten functioneel op receptorniveau gekarakteriseerd d.m.v. contractie-experimenten aan geïsoleerde gladdespier- (ileum, trachea, aorta, vas deferens) en hartspier (atrium)-preparaten, meting van intracellulaire Ca2+ concentraties en activatie van signaal transductie-eiwitten in gekweekte gladde spier- en epitheelcellen, en interactieve computer simulaties van effecten op bloeddruk en hartritme, gedrag en skeletspierfunctie. Aan het eind van het practicum worden de verkregen resultaten in samenhang gepresenteerd en wordt de opheldering van de onbekende stoffen bediscussieerd. | |||||||||||||||||||||||||||||
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| 42 | Physiology and Pharmacology | WBFA020-05 | |||||||||||||||||||||||||||
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| 43 | Proteins for Biopharmaceuticals & Drug Discovery | WBFA044-10 | |||||||||||||||||||||||||||
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| 44 | Receptor Pharmacology | WBFA036-05 | |||||||||||||||||||||||||||
| During the first semester of the propaedeutic phase, students were introduced to the main principles in physiology including defence mechanisms and immunology, and developed the ability to understand and explain these principles in the treatment approach of pathologies using pharmacological interventions, with a special focus on diabetes mellitus. In this course unit, more attention will be paid to the underlying mechanisms that play a role in our body’s functioning in healthy situations and when affected by diseases. It concerns a more in-depth study of the treatment approach to diseases by pharmacists. The following topics will be addressed in this course unit: - key definitions in pharmacology: pharmacodynamics versus pharmacokinetics - the functional mechanisms of pharmaceuticals and pharmacological definitions: agonist, antagonist, inverse agonist, receptor reserve, receptor regulation (desensitization, up/down regulation) - signal transduction mechanisms: G protein-coupled receptors, ligand-gated ion channels, kinase-coupled receptors, nuclear receptors, crosstalk between signal transduction mechanisms, the function of arrestins, ubiquitylation - basic principles of neurotransmission: presynaptic and postsynaptic receptors, co-transmission - receptor subtypes and signal transduction: the cholinergic, adrenergic, serotonergic, dopaminergic, histaminergic and purinergic systems - function of autacoids and their receptors, non-steroidal anti-inflammatory drugs (NSAIDs), the functioning of local anaesthetics. This course unit dovetails with the learning outcomes a, b, d, f, g, i and j of the Bachelor’s degree programme in Pharmacy (OER Appendix I). | |||||||||||||||||||||||||||||
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| 45 | Safe Microbiological Techniques | WBFA030-00 | |||||||||||||||||||||||||||
| Zie voor meer informatie de cursus Farmaceutische Microbiologie. | |||||||||||||||||||||||||||||
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| 46 | The Cell, a Practical Approach | WBFA010-03 | |||||||||||||||||||||||||||
| Two, or by exception three, students will form a team to perform experiments in the areas of cell biology, molecular biology, biochemistry and genetics. Some techniques are: bacterial production of a biopharmaceutical; protein purification; testing of biopharmaceutical on cancer cells; measuring the enzymatic activity of a beta-lactamase; SDS-polyacrylamide gel electrophoresis; restriction analysis of DNA/plasmids; transfection of eukaryotic cells; isolation of buccal epithelial cells; PCR; microscopy. To perform these experiments, the students will use an inquiry based lab education software (https://www.labbuddy.net/) under guidance of assistants. During the practical, each student will keep track of his/her work in a lab notebook. This notebook can and will be controlled by an assistant. After the first practical week, each student will hand in a concept of a report on the performed experiments. The assistants will give comments and advice, but not grade this version. The final report, incorporating these comments, will be graded on: completeness; clarity; critical and logical analysis of data; formulation and conclusions. | |||||||||||||||||||||||||||||
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| 47 | Thermodynamica | WBFA021-05 | |||||||||||||||||||||||||||
| - Gassen: ideale gaswet, beschrijving reële gassen, toestandsgrootheden, toestandsfuncties. - Eerste hoofdwet: arbeid, warmte, interne energie, enthalpie, isotherme en adiabatische veranderingen van interne energie en enthalpie, thermochemie. - Tweede hoofdwet: entropie, spontane processen, Gibbs energie en chemische potentiaal. - Fasenleer: fasenovergangen. - Mengsels: chemische potentiaal vloeistoffen en colligatieve eigenschappen. - Chemisch evenwicht: reactie-evenwicht, partitiecoëfficient, oplosbaarheid. | |||||||||||||||||||||||||||||
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