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Clinical Toxicology
| Faculteit | Science and Engineering |
| Jaar | 2022/23 |
| Vakcode | WMFA042-05 |
| Vaknaam | Clinical Toxicology |
| Niveau(s) | master |
| Voertaal | Engels |
| Periode | semester I b |
| ECTS | 5 |
| Rooster | rooster.rug.nl |
| Uitgebreide vaknaam | Clinical Toxicology | ||||||||||||||||||||||||||||||||
| Leerdoelen | At the end of the course, the student is able to: 1. describe the most important drug-induced toxic reactions for some important intoxications. 2. describe the differences between pharmacokinetics and toxicokinetics, apply the pharmacokinetic formulae to cases of drug overdose, correctly interpret toxicokinetic data and describe actions that have to be taken accordingly. 3. make a scientifically sound treatment plan for an intoxicated patient. 4. describe the various toxidromes and use this knowledge to recognise the most likely drug or class of drugs that caused the intoxication. 5. calculate the optimal dose for some important antidotes. 6. analyse, interpret and describe a toxicological case and make a treatment plan and evaluate it. |
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| Omschrijving | In this course the following topics are discussed: • historical overview and statistics of toxicology; • the differende between pharmacokinetics and toxicokinetics; • laboratory methods used for toxicology; • paracetamol and other analgesics; • prevention of absorption and forced elimination as a mode to reduce toxicity; • toxidromes and the associated clinical parameters; • intoxications by some metals and metal compounds; • antidotes; • toxic alcohols; • psychotropic drugs; • digoxin and calcium blockers acting on the cardiac function; • toxic plants and mushrooms; • drugs of abuse such as amphetamines, cocaine, benzodiazepines, opiates, GHB, cannabinoids, laughing gas and ketamine; • forensic toxicology; • environmental toxicology. |
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| Uren per week | |||||||||||||||||||||||||||||||||
| Onderwijsvorm |
Bijeenkomst (S), Hoorcollege (LC), Opdracht (ASM)
(Hoorcolleges: 26 uur; werkcolleges: 24 uur) |
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| Toetsvorm |
Presentatie (P), Schriftelijk tentamen (WE)
(Het tentamen bestaat uit open vragen.) |
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| Vaksoort | master | ||||||||||||||||||||||||||||||||
| Coördinator | prof. dr. D.J. Touw | ||||||||||||||||||||||||||||||||
| Docent(en) | prof. dr. D.J. Touw | ||||||||||||||||||||||||||||||||
| Verplichte literatuur |
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| Entreevoorwaarden | |||||||||||||||||||||||||||||||||
| Opmerkingen | De vakcapaciteit is 48 studenten. | ||||||||||||||||||||||||||||||||
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