Animal Experimentation

Faculteit Science and Engineering
Jaar 2020/21
Vakcode WMBY019-05
Vaknaam Animal Experimentation
Niveau(s) master
Voertaal Engels
Periode hele jaar (whole year)
ECTS 5
Rooster rooster.rug.nl

Uitgebreide vaknaam Animal Experimentation
Leerdoelen At the end of the course, the student is able:

1) to discuss on the ethical aspects and consequences of working with animals (both laboratory and field) during research projects

2) to describe the relevant legal framework and guidelines of working with animals (both laboratory and field) during their master phase

3) to design an experiment including: explain about the degree of standardization, construct a timeline, formulate hypotheses and choose the appropriate statistical tests to answer the questions. In addition, they are able to apply statistical methods to estimate a priori sample size

4) to choose and justify the appropriate experimental model, e.g. animal model or replacement

5) to demonstrate (practical) skills performing an animal study, upholding the guiding principles underlying the ethical and legal use of animals in scientific research, to judge animal wellbeing, to describe the 3 Rs (reduction, refinement and replacement), and to apply the practical skills needed to perform the master project.
Omschrijving This course is in transition to a completely new e-learning format. Please be prepared for possible change during the academic year.
The learning objectives, content and judgement will be very similar, but the format is changed to learning via videos, quizzes, and assignments.
Enrolling in this course is only finalized once you will have completed following your first instruction in NESTOR. Thereafter, selected course participants will work within a google classroom environment, where more detailed information will be provided.
The aim of the course is to prepare students starting a master research project in which they participate in animal experimentation, with respect to methodological, practical and ethical aspects. At the end the students are prepared to carry out the masterproject, under supervision of and guided by the CCD permit holder.
The course has a blended classroom format with a limited contact hours. The students complete an online portfolio after practical instructions in their master project, and conduct the theoretical part as a homework assignment. They will also participate in a tour through the animal facility to learn about practical procedures while performing their study and the people involved, and attend a contact hour with an interactive lecture when topics can be discussed.
The theoretical part consists of 5 modules containing information on (1) Ethics and researcher integrity in animal and human experimentation, (2) Rules & Regulations in animal and human experimentation, (3) Research question, experimental and statistical design, (4) Choice of experimental model and subjects, and (5) Animal experimentation in practice. By in-depth reading of scientific papers, looking up content on the internet and by self-reflection, students will learn about scientific, practical and societal aspects of working with animals during their master project. For research involving humans, students must consult with their supervisors.
Uren per week
Onderwijsvorm Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC), Werkcollege (T)
(LC-50 hrs, T-2 hrs, ASM-48 hrs, PRC-4 hrs, Self-study 36 hrs; Participation in the tour and the interactive lecture, or in their online equivalents where necessary, is obligatory to complete the course)
Toetsvorm Opdracht (AST), Practisch werk (PR), Schriftelijk tentamen (WE)
(WE-33%, AST-33%, PRC-33%-The homework assignment will be judged on: (1) Grammar and spelling, (2) argumentation, (3) creativity, (4) accuracy, (5) formation of opinions, (6) thinking process on ethical problems, and (7) text structure. A rubric is available to students. The course is pass / fail, and to pass, each of the above 7 items needs to be passed. If the work is insufficient students need to redo the assignment.)
Vaksoort master
Coördinator prof. dr. B. Helm
Docent(en) prof. dr. B. Helm
Verplichte literatuur
Titel Auteur ISBN Prijs
e-learning module
Scientific papers
Entreevoorwaarden Students need to have completed their Bachelor Degree in Biology, Life Sciences and Technology, Biomedical Sciences, Medicine, or Pharmacy. A supervisor approved planning of a master research projects involving human or animal experimentation is required.

The course is compulsory for master students planning to work with animals during their research project. Following the course is exclusively possible in combination with a research master project involving animals or humans.
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