International Genetically Engineered Machine competition

Faculteit Science and Engineering
Jaar 2021/22
Vakcode WMBS013-20
Vaknaam International Genetically Engineered Machine competition
Niveau(s) master
Voertaal Engels
Periode semester II
ECTS 20
Rooster rooster.rug.nl

Uitgebreide vaknaam International Genetically Engineered Machine competition
Leerdoelen At the end of the course, the student is able to:

1) Propose novel research questions within the field of Synthetic Biology, which ideally addresses one or more social issues (fitting within the iGEM-project);

2) Design an experimental setup to address the proposed research questions (using the tools available with the iGEMproject);

3) Perform the experiments to address the proposed research questions (using the tools available with the iGEM-project);

4) Classify their own biological system and device within national and international GMO guidelines, and perform their work accordingly;

5) Present and debate the outcomes of their biological system and device publically;

6) Evaluate their own performance and contribution within the project.
Omschrijving The iGEM (international Genetically Engineered Machine competition (http://igem.org/Main_Page)) is an international organization that stimulates engineering of novel biological devices. It addresses the question: Can simple biological systems be built from standard interchangeable parts and operated in living cells? The competition already involves more than 340 teams from many major universities and institutes around the world, all trying to actively engineer biological devices by means of Synthetic Biology. The course unit´s content includes formulating and executing an experimental and/ or computational project related to Synthetic Biology and Systems Biology and reaching the goals in Synthetic Biology that are described by the iGEM organization.

Students learn to work together in a multidisciplinary team, designing and executing a project, professionally presenting results in public, performing
outreach, and obtaining funding. They will have to provide evidence of their contribution to the project on both individual and team level. This includes planning of work meetings and practical laboratory work in the period Feb-Nov and performing research according to work plan from Jul-Aug and also in the proceeding/posterior periods (Feb-Jun and Sep-Nov); occupation can vary between 10-80%. The final results will be presented at the iGEM Jamboree in Oct in Boston, and will have to comply with the iGEM criteria (see iGEM website each year).

The course includes two modes of assessment (see also point 7). Official assessment is via an overall assessment, which includes that of an individually written report, presentation(s) during the iGEM seminars and assessment of the student's activities and contributions by at least two supervisors. The outcome of the judgement by international referees at the iGEM jamboree is not part of the assessment, because the iGEM teams are judged by different juries, restricting an objective comparison.
Uren per week
Onderwijsvorm Bijeenkomst (S), Opdracht (ASM), Practisch werk (PRC)
(Providing a report on student's involvement in and contribution to the project. No report is FAIL Presence (> 90%) at seminars given by (invited) lecturers Presence (> 75%) at group meetings throughout the project Perform at least 1 Project sub-task (e.g.,lab manager, team representative, treasurer))
Toetsvorm Presentatie (P), Verslag (R)
(Grading is PASS or FAIL.)
Vaksoort master
Coördinator PhD. S.K. Billerbeck
Docent(en) PhD. P. Alvarez Sieiro ,PhD. S.K. Billerbeck
Verplichte literatuur
Titel Auteur ISBN Prijs
Annual reports of former iGEM teams
Website: http://igem.org/Main_Page
Compilation of laboratory protocols for molecular techniques and genetic manipulation of bacteria
Scientific publications (various, depending on the scientific topic chosen for iGEM topic per year)
Entreevoorwaarden The course unit assumes prior knowledge acquired from Bachelor studies at FSE in Life Sciences and Technology (e.g. Biochemistry, Biotechnology, Chemistry, Pharmaceutical Engineering, Biology and Medical Laboratory Research) or the non-Life Sciences (Computer Science, Artificial Intelligence, Mathematics, Physics)
Opmerkingen Study load: Total 20 ECTS, involving 4 ECTS work meetings, planning and conceiving project, 12 ECTS performing experimental/computational work, 2 ECTS presentation in Boston incl. preparations, 2 ECTS reporting. In total >14 weeks full working time, scatterd over the whole period (febr-nov)

A maximum of 15 ECTS can be part of the bachelors programme in Biology or LST.
A maximum of 20 ECTS can be used in the masters programmes of Biology, Ecology & Evolution, Marine Biology or Biomolecular Sciences as elective.
Opgenomen in
Opleiding Jaar Periode Type
MSc Biology: Research  (Electives/Optional modules) - semester II keuze
MSc Biology: Science, Business and Policy  (Electives/Optional modules) - semester II keuze
MSc Biomedical Sciences: Biology of Ageing  (Electives (10 ECTS)) - semester II keuze
MSc Biomedical Sciences: Biology of Cancer and Immune System  (Electives ) - semester II verplicht
MSc Biomedical Sciences: Biology of Food and Nutrition  (Electives (10 ECTS)) - semester II keuze
MSc Biomedical Sciences: Neuroscience  (Electives (10 ECTS)) - semester II keuze
MSc Biomedical Sciences: Research  (Electives) - semester II keuze
MSc Biomedical Sciences: Science, Business and Policy  (Electives (10 ECTS)) - semester II keuze
MSc Biomolecular Sciences  (Electives/Optional modules) - semester II keuze
MSc Ecology and Evolution: Ecology and Conservation  (Electives/optional modules) - semester II keuze
MSc Ecology and Evolution: Evolutionary Biology  (Electives/optional modules) - semester II keuze
MSc Marine Biology: Research  (Electives/Optional modules) - semester II keuze