Imaging

Uitgebreide vaknaam	Imaging
Leerdoelen	At the end of the course, the student is able: - describe the principles behind the most important cellular and biomedical imaging techniques. - describe the principles behind the most important molecular imaging and structural biology techniques. - understand and describe the key features of instrumentation used in each of the structural / imaging techniques - describe the strengths and limitations of each of the structural / imaging techniques. - give examples of characteristic uses of the common methods in medical and cellular imaging. - select and suggest techniques applicable to particular biological questions. - read and understand scientific literature employing the main imaging and structural biology techniques.
Omschrijving	This course covers the technology and principles of key techniques used for imaging structures on the molecular and organismal level, spanning the life sciences from biochemistry and cellular biology to biomedical applications. Students learn the principles and applications of medical imaging, including magnetic resonance imaging (MRI), positron emission tomography (PET) and X-ray computed tomography (CT). The course also examines how related principles and techniques are employed for imaging tissues, cells and molecules. Students learn about modern electron microscopy (EM), atomic force microscopy (AFM), and super-resolution microscopy and how these techniques are used to image single molecules and cells. Going down to the atomic level, students will learn the principles and applications of the main structural biology techniques used to visualize proteins and other biomolecules on the atomic level: nuclear magnetic resonance (NMR), X-ray crystallography, and cryogenic electron microscopy (cryoEM). The course builds on knowledge gained in prior LS&T courses, such as Biochemistry for LST, Biophysics, and Spectroscopic Tools.
Uren per week
Onderwijsvorm	Hoorcollege (LC), Opdracht (ASM), Werkcollege (T) (Lectures: 30 hours. Tutorials: 16 hours. Assignments: 10 hours.)
Toetsvorm	Opdracht (AST), Schriftelijk tentamen (WE), Verslag (R) (Written exam with open and multiple-choice questions (60%), report (20%), assignments (20%).)
Vaksoort	bachelor
Coördinator	prof. dr. P.C.A. van der Wel
Docent(en)	Prof. Dr. A. Guskov ,prof. dr. W.H. Roos ,prof. dr. P.C.A. van der Wel
Verplichte literatuur	Titel Auteur ISBN Prijs Methods in Molecular Biophysics; Structure, Dynamics, Function for Biology and Medicine, 2nd edition Nathan R. Zaccai, Igor N. Serdyuk, Joseph Zaccai
Entreevoorwaarden	Builds on knowledge from: Biochemistry for LST, Biophysics, Spectroscopic Tools
Opmerkingen
Opgenomen in	Opleiding Jaar Periode Type BSc Life Science and Technology 2 semester II a verplicht