Intro. to Nanomed. and Drug Targeting

Uitgebreide vaknaam	Introduction to Nanomedicine and Drug Targeting
Leerdoelen	At the end of the course, the student is able to: - describe different strategies for drug targeting, personalized medicine and theranostics; - describe recent developments in the field of nanomedicine and drug targeting and related innovative therapeutical strategies; - describe different innovative experimental approaches for the development of nanomedicines and targeted drugs, including monoclonal-based therapies, nanoparticle-based therapies and protein-based drug targeting strategies; - explain the different physiological barriers to drug delivery and (immune) cell-based clearance mechanisms, as well as describe the cellular uptake and intracellular distribution of nanomedicines and targeted drugs and their consequences; - justify the usage of drug carriers; - list the various types of drug carriers and their characteristics, as well as describe their advantages and disadvantages; - list and describe approved nanomedicines; - present the above to their peers.
Omschrijving	Overview The course consists of the following topics: - Personalized medicine and theranostics - Drug targeting; basic principles - Monoclonal anitibodies and modified forms thereof - Drug delivery using nano-sized carriers - Types of drug carriers - Pharmacokinetics of drug carriers - Cellular uptake and intracellular distribution of drug carriers - Stimuli-responsive drug carriers and nanomedicine for photothermal and photodynamic therapies - Nanomedicine for imaging and diagnosis - Overview of the currently approved nanomedicines, including RNA based drugs and recent vaccines against COVID19 - Barriers for drug carriers and nanomedicines Hours per week
Uren per week
Onderwijsvorm	Hoorcollege (LC), Opdracht (ASM), Werkcollege (T) (Teaching method Lectures and tutorials for the preparation of infographics in groups (2 hours a day for 2.5 weeks))
Toetsvorm	Opdracht (AST), Schriftelijk tentamen (WE) (Assessment Written exam and preparation of 3 infographics (70% and 30% of the final grade respectively). Students should pass all assessments.)
Vaksoort	bachelor
Coördinator	prof. dr. K. Poelstra
Docent(en)	P.H.C. Åberg, PhD. ,Prof. Dr. A. Salvati
Entreevoorwaarden
Opmerkingen	Cap. 40 students
Opgenomen in	Opleiding Jaar Periode Type BSc Farmacie  (hoofdprogramma) 3 semester II b keuzegroep D