Biochemistry and biotechnology

Uitgebreide vaknaam	Biochemistry and biotechnology
Leerdoelen	At the end of the course, the student is able to: 1. describe (and draw simple examples of) structures, chemical properties, and role of the most important classes of biomolecules: DNA, RNA, proteins, lipids and carbohydrates 2. describe and explain the mechanism of transcription and translation 3. recognize the main forces of interaction between biomolecules 4. describe the kinetics and thermodynamics of enzym catalysed reactions 5. make simple calculations on the kinetics of enzymes and the thermodynamics of biologically relevant reactions 6. analyze sequences and structures of biomolecules 7. describe the binding of small molecules to proteins, and explain and interpret the consequences of the concept of allostery
Omschrijving	The course provides insight in the chemical basis of life. Biology often looks overwhelmingly complex through the eyes of chemists, but the underlying chemical and physical concepts are surprisingly simple. The course will teach students which macromolecules constitute life, and how the interplay between them forms the basis of life. Apart from teaching the theoretical background in biochemistry, the course also introduces a number of essential biochemical experimental techniques. The course is based on the book Biochemistry (Berg et al., 8h edition). It explores the function and mechanism of essential biomolecules, covering DNA, RNA, proteins, carbohydrates and lipids. There will be emphasis on (1) the mechanism of transcription & translation, and (2) the structure & function of proteins. Furthermore, several experimental techniques will be explained which serves as preparation for the Biochemistry practical course (CHBCP-10).
Uren per week
Onderwijsvorm	Hoorcollege (LC), Werkcollege (T) (Workload: Self study 108 hrs, Lecture 24 hrs, Tutorial 8 hrs,)
Toetsvorm	Schriftelijk tentamen (WE) (Final mark: Written exam 100%)
Vaksoort	propedeuse
Coördinator	dr. J. Broos
Docent(en)	dr. J. Broos ,dr. M.H.K. Linskens , C. Mayer, PhD.
Verplichte literatuur	Titel Auteur ISBN Prijs Biochemistry (9th edition) Berg et al 9781319114657
Entreevoorwaarden	The course assumes basic chemistry knowledge form previous courses, and some general (secondary school) basic biology knowledge
Opmerkingen	Pass mark: 5.5
Opgenomen in	Opleiding Jaar Periode Type BSc Chemical Engineering 1 semester II a verplicht BSc Chemistry  ( Core programme) 1 semester II a verplicht BSc Courses for Exchange Students: Chemistry - Chemical Engineering - semester II a