Research Skills in Life Sciences 3

Faculteit Science and Engineering
Jaar 2021/22
Vakcode WBBY068-05
Vaknaam Research Skills in Life Sciences 3
Niveau(s) propedeuse
Voertaal Engels
Periode semester II b
Rooster BN BMS MLS

Uitgebreide vaknaam Research Skills in Life Sciences 3
Leerdoelen At the end of the course the student is able to:
- Use the provided theoretical content to interpret and explain topic related problems;
- Summarize the general principles of biochemical techniques;
- Apply basic biochemical techniques;
- Analyse and report data from biochemical experiments;
- Critically analyse and evaluate a research article;
- Present a research article's line of reasoning.
Omschrijving In the course, students learn academic as well as practical skills in the Life Sciences. The academic skills focus on the critical reading and interpretation of scientific research papers using primary research literature distributed over topics representing three majors in the bachelor programme: Biomedical Sciences, Behaviour & Neurosciences and Molecular Life Sciences. Students can express preference for one of the topics which all share the same learning goals. Assignment will be based, on personal preference as well as capacity. The topics focus on 1) the cardiovascular system/heart failure; 2) neural regulation of social behavior; and 3) molecular aspects of Parkinson Disease. The training of academic skills will take 4 weeks. During several lectures students will receive background information on the topics in the academic skills block. During tutorials, students learn to distinguish structure - elements such as motive, purpose, arguments and conclusions - in the text of research papers using the Scientific Argumentation Model (SAM). After approximately 3 weeks of each reading block, the knowledge of the students on the topic will be tested in an exam (multiple choice). In the final week of the block, students will be tested via individual presentations on their ability to quickly read, summarize and comment on a paper. Other tasks may form part of the assignments.

In the practical part of the course, students will become familiar with different molecular biology techniques, and apply principles learned during theoretical courses from the 1st year. The student will solve an authentic problem: i.e. producing vanillin in an environmentally friendly and cheap way. To this end, the students develop an expression vector and produce a recombinant enzyme. In the second week they purify the enzyme and characterize it. The students will also design and perform necessary experiments to produce the highest amount of vanillin by using the enzyme that they prepared.
Uren per week
Onderwijsvorm Opdracht (ASM), Werkcollege (T)
(T-12 hrs, A-80 hrs, self-study 48 hrs)
Toetsvorm Presentatie (P)
(P-100% (Grade for presentation should 6 or higher))
Vaksoort propedeuse
Coördinator prof. dr. D.J. Scheffers
Docent(en) prof. dr. R.H. Henning ,prof. dr. A. Kortholt ,dr. R.T. Molenhuis
Verplichte literatuur
Titel Auteur ISBN Prijs
Course Manual Biochemistry practical
Entreevoorwaarden No prior knowledge required.

This course unit is only accessible to students enrolled in the Bachelor's programmes Biology or old curriculum Life Science & Technology. Students following other degree programmes cannot follow this course unit and will be unenrolled in Progress.
Opmerkingen Guest lecturers: Dr. J. Broos, Dr. H. van Duinen, prof. dr. J.H. Hillebrands, dr. J.H.J. Muntinga, dr. R.G. Schoenmaker, prof. Dr. A. Scheurink, Dr. M.H.K. Linskens

Practical is mandatory; missing out too many hours (as deemed by instructors) will result in having to redo the practicals.
Tutorials are mandatory; the likelihood of different timeslots for the same tutorial may allow taking the tutorial with another group. Missing two or more tutorials will result in failing the course.

Research Skills in Life Sciences 1, 2, and 3 must be taken together in order to pass the course "Research Skills in Life Sciences" (10 ECTS)
Opgenomen in
Opleiding Jaar Periode Type
BSc Biology - Year 1 1 semester II b verplicht BN/BMS/ML
BSc Biology: major Behaviour and Neurosciences 1 semester II b verplicht
BSc Biology: major Biomedical Sciences 1 semester II b verplicht
BSc Biology: major Integrative Biology  (Semester 2, BN/BMS/ML route) 1 semester II b verplicht
BSc Biology: major Molecular Life Sciences 1 semester II b verplicht