Molecular Research in Human Disease

Uitgebreide vaknaam	Molecular Research in Human Disease
Leerdoelen	At the end of the course, the student is able to: 1) Think critically with a view to solving problems. 2) Interpret a high-impact scientific paper, identify the importance of the data and write an editorial based on its novelty. 3) Interpret a result section and write a scientific abstract. 4) Apply practical skills to solving problems. 5) Prepare a research proposal outlining a proposed area of study 6) Communicate complex ideas clearly, concisely and critically
Omschrijving	In this course (5 ECTS) the students are prepared for a research career in science. Students learn the necessary skills to design and conduct scientific research. They are introduced into various molecular and biochemical techniques and learn about the use of genetically engineered mouse models in unravelling the mechanism of human disease. Students will write an editorial based on a high-impact scientific article and they will devise a research proposal for research into human diseases. Furthermore, students will present their editorial and research proposal to learn to communicate their ideas effectively. Based on the principal of Problem Based Learning, the students also have to solve three cases related to different diseases or aspects there off. In addition, they participate in a 4-day practical session in which they produce results that have to be discussed in their case report. As a result, our course is very different from the other courses in the Bachelor Programme and the students need to present an active attitude, a high level of independence and intrinsic motivation to be able to successfully pass our course. Every single component is graded and thus, the overall score is a good reflection of the student's ability to be successful in a future scientific career.
Uren per week
Onderwijsvorm	Bijeenkomst (S), Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC), Werkcollege (T) (LC-13 hrs, T-10hrs, S-6hrs, ASM1-24 hrs, ASM2-8hrs, ASM3-60hrs, PRC-21 hrs)
Toetsvorm	Opdracht (AST), Presentatie (P), Verslag (R) (ASM Problem Solving 30%, ASM Abstract 20%, Editorial 25% (R 50%, P 50%), Research Proposal 25% (R 50%, P 50%). Final grade > 5.5)
Vaksoort	bachelor
Coördinator	dr. D.P.Y. Koonen
Docent(en)	Guest lecturer ,dr. D.P.Y. Koonen ,prof. dr. ir. A.J.A. van de Sluis ,dr. D.S. Verbeek
Entreevoorwaarden	The course units assumes prior knowlegde and skills, acquired from the following other course units and/or degree programmes : Molecular Genetics, Research skills in Life Sciences PLEASE NOTE This course unit is only accessible to students enrolled in the Bachelor's programmes Biology or old curriculum Life Science & Technology. Students following other degree programmes cannot follow this course unit and will be unenrolled in Progress.
Opmerkingen	Guest lectuers: Jan-Albert Kuivenhoven, Joram Mooiweer, Janine Kruit, Marit Westerterp, Maaike Oosterveer, Hans Jonker, Folkert Kuipers, Alain de Bruin (UU). Capacity: max. 20 students All parts are mandatory. Failure to present the editorial and research proposal will result in a 0 score on these items, unless the student can proof that absence was due to illness. In that case the student is entitled to present at a later time point. Students who participated in an earlier edition of the course are exempted from those course elements for which they previously obtained a sufficient grade for; in such cases, the partial grade for these course elements (e.g. PBL cases, assignments) obtained earlier remains valid.
Opgenomen in	Opleiding Jaar Periode Type BSc Biology: major Biomedical Sciences 2 semester II b keuze