Evolutionary and Ecological Genomics

Uitgebreide vaknaam	Evolutionary and Ecological Genomics
Leerdoelen	At the end of the course, the student is able to: 1. Describe the forces that drive the evolution of prokaryotic and eukaryotic organisms. 2. State the nature and dynamics of genetic variation within prokaryotic and eukaryotic populations and species in relation to their environment 3. Describe how the complexity of the genome can accommodate (promote and constrain) the adaptation of different organisms (prokaryotes and eukaryotes) 4. Define evolutionary processes, such as selection at different organizational levels, genetic drift, and horizontal gene transfer 5. Assess how evolutionary processes affect genomic changes and can they be recognized at the genomic level 6. Asses how to use metagenomics to analyze complex prokaryotic communities
Omschrijving	The aim of the course is to present how the complexity of the genome of prokaryotes and eukaryotes, in relation to the complexity of the ecosystem, affects ecological and evolutionary processes at different levels. A central theme is how variation at the level of genotypes leads to variation in phenotypes, in interaction with environmental settings. Students will be familiar with population genetic processes such as mutation, genetic drift, horizontal gene transfer, migration and selection. They will learn how these processes become evident at the genetic level and can lead to evolutionary changes and constraints. They will be instructed to evaluate how selection can act at different organizational levels, such as genic and individual selection. They will acquire knowledge about metagenomics and genomic techniques and how these can be used to address ecological and evolutionary questions on prokaryotes and eukaryotes.
Uren per week
Onderwijsvorm	Hoorcollege (LC), Opdracht (ASM) (LC-24 hrs; ASM-54 hrs (poster); Self study-50 hrs)
Toetsvorm	Opdracht (AST), Schriftelijk tentamen (WE) (WE-50% (open book) exam; AST-50% (essay))
Vaksoort	bachelor
Coördinator	prof. dr. J. Falcao Salles
Docent(en)	dr. ir. M.G.J. de Vos ,dr. S.J.J. Lequime ,dr. G.S. van Doorn ,prof. dr. B. Wertheim
Verplichte literatuur	Titel Auteur ISBN Prijs No required book. Literature (overview articles, as well as research articles) will be provided during the course. For the presentation additional literature search needs to be performed.
Entreevoorwaarden	The course units assumes prior knowlegde and skills from year 1 Biology. PLEASE NOTE Biology and Life Science & Technology (old curriculum) course units are only accessible for students of those degree programmes. Students from other degree programmes who would like to participate in Biology course units are obliged to contact one of the academic advisors before registration. After this contact, students have to request admission from the Board of Examiners Biology/Life Science & Technology. Failing to follow this procedure results in immediate unenrollment without prior notification.
Opmerkingen	During the presentations the presence is mandatory. During the lectures and practical work the presence is not mandatory, however the grade depends for 10% on student participation during the lectures. The open book written exam is mandatory and a minimal grade should be 5.5. the possibility to resit exam will be planned in the schedule Capacity max: 60 students Dit vak had vorig jaar vakcode WBLS19037
Opgenomen in	Opleiding Jaar Periode Type BSc Biology: major Behaviour and Neurosciences 2 semester II b keuze BSc Biology: major Ecology and Evolution 2 semester II b keuze BSc LS&T: major Behaviour and Neurosciences (cohort 2018 and 2019) 2 semester II b keuze