Bio-organic Chemistry
Faculteit | Science and Engineering |
Jaar | 2021/22 |
Vakcode | WBBY050-05 |
Vaknaam | Bio-organic Chemistry |
Niveau(s) | bachelor |
Voertaal | Engels |
Periode | semester II b |
ECTS | 5 |
Rooster | rooster.rug.nl |
Uitgebreide vaknaam | Bio-organic Chemistry | ||||||||||||||||
Leerdoelen | At the end of the course students should be able to: 1. name and draw structures of molecules containing functional groups, including conformations and configurations 2. explain and recognize the different types of elimination and addition reactions in simple organic molecules 3. define the concepts of conjugation and aromaticity and recognize these concepts in given organic molecules 4. describe the mechanism of electrophilic aromatic substitution and apply this in synthesis 5. define the regioselectivity pattern of electrophilic aromatic substitution in substituted benzenes 6. reproduce and recognize addition reactions on aldehydes, ketones, carboxylic acid derivatives and alpha,beta unsaturated carbonyl compounds including imine formation, (hemi)-acetal formation and conjugate addition 7. recognize and apply enol and enolate formation of aldehydes, ketones and carboxylic acid derivatives in the formation of carbon-carbon and carbon-hydrogen bonds 8. recognize and apply the concepts presented in the points 1-7 to (straightforward) carbohydrates thereby understanding the metabolism of carbohydrates. 9. recognize and apply the concepts presented in the points 1-7 to amino acids, peptides, glycolysis pathway and the citric acid cycle. |
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Omschrijving | The aim of this course is to gain insight in a number of important reactivity principles in Bio-organic Chemistry. A focal point is the understanding and the application of several reaction types that form the basis of cell metabolism, and to get insight in the structure and reactivity of molecules. Function and reactivity of molecules is discussed in the context of the living cell. | ||||||||||||||||
Uren per week | |||||||||||||||||
Onderwijsvorm |
Hoorcollege (LC), Werkcollege (T)
(LC-24 hrs, T-24 hrs, Self-study 92 hrs) |
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Toetsvorm |
Schriftelijk tentamen (WE)
(WE-100%. The final mark is the mark of the exam.) |
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Vaksoort | bachelor | ||||||||||||||||
Coördinator | dr. N.R.M. Reintjens | ||||||||||||||||
Docent(en) | prof. dr. ir. A.J. Minnaard ,dr. N.R.M. Reintjens | ||||||||||||||||
Verplichte literatuur |
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Entreevoorwaarden | Prior knowledge: Molecules of Life. It is not permitted to take this course unit together with Organic and Biosynthesis and Pharmaceutical Biosynthesis (Pharmacy) in a single Bachelor’s programme because of too much overlap in the curriculum. PLEASE NOTE Students from other degree programmes than Biology and/or Life Science & Technology who would like to participate in this course unit need to have obtained a pass for the course Molecules of Life or a similar course. Students are obliged to contact one of the academic advisors before enrolling in this course in order to check whether they have met de entrance requirements. After this contact, students also have to request admission from the Board of Examiners Biology/Life Science & Technology. Failing to follow this entire procedure before the official enrollment deadline, results in immediate unenrollment without prior notification. Students from the Bachelor's degree programmes Biology and Life Science & Technology take priority over students from other degree programmes when the course has a maximum capacity. |
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Opmerkingen | The final mark is the mark of the exam. It is estimated that 50% of the exam is testing whether the student can reproduce the content of the course, 40% whether the student can apply the content (solving problems), and 10% whether the student has deeper insight and abstraction. The exam plus grading scheme are sent to the ESC. A typical exam contains 100 points. | ||||||||||||||||
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