Immunology and Disease

Faculteit Science and Engineering
Jaar 2021/22
Vakcode WBBY043-05
Vaknaam Immunology and Disease
Niveau(s) bachelor
Voertaal Engels
Periode semester II a

Uitgebreide vaknaam Immunology and Disease
Leerdoelen At the end of the course, the student is able to:
1) Outline and explain fundamental immunological mechanisms required for combating infections
2) Outline and explain immunological mechanisms underlying development of immune mediated diseases including
autoimmune disease, asthma and allergies, transplant rejection and cancer.
3) Correctly apply antibody based immunological techniques in research and diagnosis of immune-mediated diseases
Omschrijving The immune system is critical for combating infectious diseases, and its activity can be exploited for the treatment of numerous diseases, including cancer. Dysregulated activity of the immune system lies at the heart of the pathogenesis of numerous diseases, including auto-immune disorders, allergy, asthma, and cancer. Our insight into the immunological basis of these diseases and the possibilities for rational design of innovative therapeutic strategies for their prevention or treatment is progressing at a rapid pace.

In this course, students will obtain basic theoretical knowledge regarding fundamental immunological mechanisms to combat infections and their role in immune-mediated diseases. In addition, students will obtain theoretical knowledge regarding immunological techniques and methods to analyse immune responses and how these can be applied for research, diagnostic and therapeutic purposes. This knowledge will be imparted by overview lectures given by expert principal investigators of the UMCG and the RUG. During the practicals, students will become familiar with the execution and application of antibody-based immunological techniques including immunohistochemistry, enzyme-linked immunosorbent assay and flow cytometry.

Finally, since immunology is a vast developing field in which novel technologies and concepts are implemented to understand disease mechanisms and identify new targets for treatment of immune mediated diseases. Many papers are published daily and many of these are quite complex. To be able to understand novel scientific information analytical reading skills are essential. In this assignment students will train their analytical reading skills for scientific papers by summarizing the main points and how to communicate these to a broader audience in a graphical abstract
Uren per week
Onderwijsvorm Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC)
(LC-25hrs, ASM-20hrs, PRC-35 hrs, self-study 60 hrs)
Toetsvorm Meerkeuze toets (MC), Opdracht (AST)
(MC-75%, AST-25%. Pass mark: 5.5)
Vaksoort bachelor
Coördinator prof. dr. R.A. Bank
Docent(en) prof. dr. C.A.H.H. Daemen ,prof. dr. P. de Vos , Guest lecturer ,prof. dr. A.L.W. Huckriede ,dr. ir. M.C. Nawijn
Verplichte literatuur
Titel Auteur ISBN Prijs
Cellular and Molecular Immunology 10th 2021 Abul Abbas Andrew H. Lichtman Shiv Pillai 9780323757485 €  75,00
Entreevoorwaarden Immunology

This course unit is only accessible to students enrolled in the Bachelor's programmes Biology or old curriculum Life Science & Technology. Students following other degree programmes cannot follow this course unit and will be unenrolled in Progress.
Opmerkingen Practicals and assignment are mandatory. Consequence for missing practicals/not handing in assignment is that no final grade for the course will be given.

Guest lecturers: B.J. Kroesen, C.A. Stegeman, A. Rutgers, J.N.G. Oude Elberink, J.L. Hillebrands

Maximum capacity: 50 students
Opgenomen in
Opleiding Jaar Periode Type
BSc Biology: major Biomedical Sciences 2 semester II a keuze
BSc Biology: major Integrative Biology  (Option B: students who follow Res. Project 1 within the major EE) 3 semester II a keuze
BSc Biology: major Molecular Life Sciences 3 semester II a keuze
BSc LS&T: major Molecular Life Sciences (cohort 2018 and 2019) 3 semester II a keuze