Immunology and Disease

Faculteit Science and Engineering
Jaar 2020/21
Vakcode WBBY043-05
Vaknaam Immunology and Disease
Niveau(s) bachelor
Voertaal Engels
Periode semester II a

Uitgebreide vaknaam Immunology and Disease
Leerdoelen At the end of the course, the student is able to:
1) Outline and explain fundamental immunological mechanisms required for combating infections
2) Outline and explain immunological mechanisms underlying development of immune mediated diseases including
autoimmune disease, asthma and allergies, transplant rejection and cancer.
3) Correctly apply antibody based immunological techniques in research and diagnosis of immune-mediated diseases
Omschrijving The immune system is critical for combating infectious diseases, and its activity can be exploited for the treatment of numerous
diseases, including cancer. Dysregulated activity of the immune system lies at the heart of the pathogenesis of numerous diseases,
including auto-immune disorders, allergy, asthma, and cancer. Our insight into the immunological basis of these diseases and the
possibilities for rational design of innovative therapeutic strategies for their prevention or treatment is progressing at a rapid pace.
In this course, students will obtain basic theoretical knowledge regarding fundamental immunological mechanisms to combat
infections and their role in immune-mediated diseases. In addition, students will obtain theoretical knowledge regarding
immunological techniques and methods to analyse immune responses and how these can be applied for research, diagnostic and
therapeutic purposes. This knowledge will be imparted by overview lectures given by expert principal investigators of the UMCG and
the RUG. During the practicals, students will become familiar with the execution and application of antibody-based immunological
techniques including immunohistochemistry, enzyme-linked immunosorbent assay and flow cytometry.
Uren per week
Onderwijsvorm Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC)
(Traditional lecture 25 hrs, Assignment on immunological problem 5 hrs, Practicals immunological techniques 35 hrs, Self study 75 hrs.)
Toetsvorm Meerkeuze toets (MC), Opdracht (AST), Practisch werk (PR)
(Pass mark: 5.5 Calculated using grades for MC exam (90%) + assignment (10%). Brief report on practicals needs to be complete and handed in.)
Vaksoort bachelor
Coördinator prof. dr. R.A. Bank
Docent(en) prof. dr. C.A.H.H. Daemen ,prof. dr. P. de Vos ,prof. dr. A.L.W. Huckriede ,prof. dr. F.G.M. Kroese ,dr. B.J. Kroesen ,dr. ir. M.C. Nawijn ,dr. J.N.G. Oude Elberink ,dr. A. Rutgers ,prof. dr. C.A. Stegeman
Verplichte literatuur
Titel Auteur ISBN Prijs
Cellular and Molecular Immunology, 9th edition, year 2017 Abul Abbas  Andrew H. Lichtman  Shiv Pillai 9780323479783 €  70,00
Entreevoorwaarden Prior knowledge: Immunology (year 2, 1b)

Biology and Life Science & Technology (old curriculum) course units are only accessible for students of those degree programmes. Students from other degree programmes who would like to participate in Biology course units are obliged to contact one of the academic advisors before registration. After this contact, students have to request admission from the Board of Examiners Biology/Life Science & Technology. Failing to follow this procedure results in immediate unenrollment without prior notification.
Opmerkingen Capacity max: 50 students

Practicals are mandatory. Consequence for missing practicals is that no final grade for the course will be given.

Dit vak had vorig jaar vakcode WBLS19028
Opgenomen in
Opleiding Jaar Periode Type
BSc Biology: major Biomedical Sciences 2 semester II a keuze
BSc Biology: major Integrative Biology  (Option B: students who follow Res. Project 1 within the major EE) 3 semester II a keuze
BSc Biology: major Molecular Life Sciences 3 semester II a keuze
BSc LS&T: major Biomedical Sciences (cohort 2018 and 2019) 2 semester II a keuze
BSc LS&T: major Molecular Life Sciences (cohort 2018 and 2019) 3 semester II a keuze