Advanced Pharmacoeconomics

Uitgebreide vaknaam	Advanced Pharmacoeconomics
Leerdoelen	At the end of the course, the student is able to: 1) critically review model-based economic evaluations and their results. 2) design and program a health economic decision model, to evaluate a certain health intervention in a specified patient population. 3) use a health economic decision model for performing cost-effectiveness analysis and interpret the outcomes. 4) understand what is needed for a state of the art model validation. The student is able to explain the theory and methods of model validation and why validation is required. 5) undertake state of the art uncertainty analysis. 6) understand the role of value of information analysis 7) assess what input parameters are needed to populate a health economic decision model, to search for relevant sources and to apply the correct statistical analyses to estimate or transform input parameters, either taken from literature, or based on aggregate or patient level data.
Omschrijving	Students will learn to design, implement, and analyse health economic decision models. An important application of these models are cost-effectiveness analyses. They will learn to judge what input data are needed to populate their model and from what sources these can be obtained. Model types covered are: decision trees, macro level state transition models (Markov cohort models), and patient-level models. The differences between these models, for example in how patient heterogeneity is handled, will be explored. Several statistical techniques needed to obtain useful input data including parametric survival analysis will be discussed. Insight into the role of sensitivity analysis and the different options for this will be given. This includes probabilistic sensitivity analysis and value of information analysis.
Uren per week	variabel
Onderwijsvorm	Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC) (LC: 19 hrs, also containing flipped class room lectures, 76 hrs assignment, 16 hrs practical, 29 hrs self study)
Toetsvorm	Presentatie (P), Verslag (R) (Report: 50% and Presentation: 50% To pass the course a total grade of 5.5 or more is required, as well as attendance in at least 80% of lectures and practicals. For each separate item at least a grade of 5 should be obtained.)
Vaksoort	master
Coördinator	prof. dr. T.L. Feenstra
Docent(en)	prof. dr. T.L. Feenstra ,dr. A.D.I. van Asselt
Verplichte literatuur	Titel Auteur ISBN Prijs Afhankelijk van het onderwerp diverse gepubliceerde methodologische artikelen / various methodological publications Decision Modelling for Health Economic Evaluation, Oxford University Press, 2008 Briggs A, Claxton K, Sculpher M. ca. €  50,00
Entreevoorwaarden	Students are assumed to have a basic level of knowledge of economic evaluation at the level of the textbook by Drummond et al. e.g. obtained by attending the course Pharmacoeconomics, or the course Economic Evaluation in Healthcare. Students are also assumed to have knowledge of Microsoft Excel and to have a basic level of statistical knowledge. Students who have doubts about their background knowledge are advised to contact the course coordinator prior to the start date of the course.
Opmerkingen	Capacity is 15 students. Updated 29-04-2021 LW
Opgenomen in	Opleiding Jaar Periode Type MSc BA - Health  (keuzevakken B MSc BA Health) 1 semester I b keuze MSc Courses for Exchange Students: Pharmacy - semester I b MSc Farmacie  (Keuzevakken) - semester I b keuze MSc Medical Pharmaceutical Sciences: Drug Toxicology & Translational Technology  (Electives) - semester I b keuze MSc Medical Pharmaceutical Sciences: Pharmaceutical Design and Engineering  (Other possible Electives) - semester I b keuze MSc Medical Pharmaceutical Sciences: Pharmacoepidemiology & Pharmacoeconomics  ( Track choice) - semester I b keuze MSc Medical Pharmaceutical Sciences: Research  (Electives) - semester I b keuze MSc Medical Pharmaceutical Sciences: Science, Business and Policy  (Electives ) - semester I b keuze