Supramolecular chemistry

Uitgebreide vaknaam	Supramolecular chemistry
Leerdoelen	At the end of this course, student is able to 1: explain the different types of noncovalent interactions and show how to quantify these 2: explain that the simultaneous action of several noncovalent interactions can give rise to different forms of cooperativity (chelate and allosteric). 3: recognise the most common synthetic receptors and self-assembled structures and materials, including self-assembled monolayers and polymers. 4: explain the basic kinetics of self-replicating molecules. 5: explain the principles and applications of dynamic combinatorial chemistry. 6: explain the concepts and challenges in supramolecular catalysis. 7: contrast the difference between systems under thermodynamic control, kinetic control and systems that are far-from-equilibrium. 8: discriminate between self-assembled and self-organized systems 9: enumerate the non-covalent and covalent interactions that comprise self-assembled monolayers 10: predict whether or not a molecule will form a self-assembled monolayer under specific conditions
Omschrijving	This course is an introduction to supramolecular chemistry in which recent examples are used to elaborate on the background and most important principles. First, the most important non-covalent interactions will be explained. We will then see how these interactions can act in concert to give rise to well-defined supramolecular structures, including: host-guest chemistry, self-assembled structures and materials. This will be followed by a treatment of the interplay between noncovalent chemistry and covalent chemistry as seen in dynamic covalent chemistry, dynamic combinatorial chemistry, supramolecular catalysis and self-replication. After that far-from-equilibrium systems will be introduced, including far-from-equilibrium self-assembly, molecular motors. Further topics that will be treated include nanoparticles, self-assembled monolayers, the supramolecular chemistry of polymers, using recent examples from the literature that exemplify the phenomena involved and the utility and constraints of using molecules in bottom-up fabrication.
Uren per week
Onderwijsvorm	Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC) (Total hours of lectures: 20 hours, homework assignments: 120 hours, tutorials: 3 hours, literature presentations: 2 hours.)
Toetsvorm	Practisch werk (PR), Presentatie (P), Schriftelijk tentamen (WE) (Grade contributiion: 70% written exam, 20% presentation, 10% practical work. See remarks.)
Vaksoort	master
Coördinator	prof. dr. S. Otto
Docent(en)	prof. dr. R.C. Chiechi ,prof. dr. K.U. Loos ,prof. dr. S. Otto ,dr. M.C.A. Stuart
Verplichte literatuur	Titel Auteur ISBN Prijs The handouts and readers compiled specifically for this course are mandatory literature.
Entreevoorwaarden	The course unit assumes prior knowledge acquired from Organic Chemistry 2 and Physical Chemistry 2, from the Bachelor Chemistry degree program.
Opmerkingen	Max number of points is 100. Mark = number of points / 10, rounded off to the nearest 0.5 mark (except between 5 and 6, where rounding takes place to the nearest integer mark). Marking of literature presentations is based on the student's understanding of the content and conclusions, connection to the context and critical analysis of contents and their implications for the field. Pass mark: 6 The practical course is mandatory. If the student misses this component for a valid reason (s)he will have to do a similar practical assignment at a later moment. This course was registered last year with course code CHC3133E
Opgenomen in	Opleiding Jaar Periode Type MSc Chemistry: Advanced Materials  (Electives) - semester II a keuze MSc Chemistry: Advanced Materials  ( Core Programme) - semester II a keuzegroep MSc Chemistry: Catalysis and Green Chemistry  (Electives) - semester II a keuze MSc Chemistry: Chemical Biology  (Electives) - semester II a keuze MSc Chemistry: Erasmus Mundus Theoretical Chemistry and Computing Modelling  (Electives) - semester II a keuze MSc Chemistry: Science, Business and Policy  (Electives) - semester II a keuze MSc Courses for Exchange Students: Chemistry - Chemical Engineering - semester II a MSc Nanoscience  (Optional Courses) - semester II a keuze MSc Physics: Advanced Materials  ( Compulsory courses) - semester II a keuzegroep