Ocasys: Ocasys: Online Onderwijscatalogus

Rijksuniversiteit Groningen

Hieronder staan het programma en de vakomschrijvingen van MSc Medical Pharmaceutical Sciences: Pharmacoepidemiology & Pharmacoeconomics Klik op de naam van een vak in een schema om naar de omschrijving te gaan.

Periode	Type	Code	Naam	Taal	ECTS	Uren
» General Outline
hele jaar	verplicht	WMMP001-05	Colloquium	Engels	5
	verplicht	WMMP002-05	Essay	Engels	5
	verplicht	WMMP901-40	Research Project 1	Engels	40
	verplicht	WMMP902-30	Research Project 2	Engels	30
semester I	verplicht	GKCPE001	CPE - Basics in Medicine	Engels	8
semester I a	verplicht	WMMP012-05	Academic Skills	Engels	5
	verplicht	WMMP015-05	Clinical Pharmacoepidemiology	Engels	5
	verplicht	WMMP006-05	Drug Development: from Design to Evaluation	Engels	5

Opmerkingen	All elements in the general outline are mandatory* for the P&P-track. First year students should start with the four mandatory courses listed above. The course Basics in Medicine from the Faculty of Medical Science is also a mandatory course within the P&P-track. Please contact Prof. E. Hak to enrol. For information on the schedule, see the Student Portal: https://student.portal.rug.nl/infonet/studenten/fse/programmes/msc-mps/curriculum/programmeplanning Students who passed the equivalent course far-epi (=farmacoepidemiologie/pharmacoepidemiology) in their bachelor will be exempted from Clinical Pharmacoepidemiology. The remaining 5 ECTS should be considered as 5 ECTS extra electives in their master programme If you wish to do a Research Assignment, please see the Student Portal for more information: https://student.portal.rug.nl/infonet/studenten/fse/programmes/msc-mps/curriculum/electives Codes for grading the Research Assignment: WMMP014-05, WMMP014-10 or WMMP014-15, depending on the amount of ECTS (5, 10 or 15)
» Track choice
Periode	Type	Code	Naam	Taal	ECTS	Uren
semester I a	keuzegroep A	WMFA040-05	Pharmacoeconomics	Engels	5	40
	keuzegroep A	WMFA041-05	Pharmaco-epidemiology in Practice	Engels en Nederlands	5
semester I b	keuze	WMFA001-05	Advanced Pharmacoeconomics	Engels en Nederlands	5	variabel
	keuze	WMMP010-05	Reproductive Toxicology and Epidemiology	Engels	5
semester II a	keuze	WMMP011-05	Pharmacovigilance (2022/2023)	Engels	5

Opmerkingen	Choose (at least) 1 from option group A. Students who did Introduction to Pharmacoeconomics in their Bachelor could also only take Advanced PharmacoEconomics. The other courses in the table above are suggestions especially suitable as master courses for the P&P track.
» Electives
Periode	Type	Code	Naam	Taal	ECTS	Uren
semester I	keuze	WMSE002-10	Introduction Science and Policy	Engels	10	40
	keuze	WMMP004-01	Microbiological Safety	Engels	1	16
semester I a	keuze	WMMP005-05	Advanced pharmacokinetics	Engels	5
	keuze	WMBC003-05	Behavioural Pharmacology	Engels	5
	keuze	WMBM008-05	From Big Data to Personalised Medicine	Engels	5
	keuze	WMSE001-10	Introduction Science and Business	Engels	10
	keuze	WMMP007-05	Molecular Toxicology	Engels	5
	keuze	WMMP008-05	Pharmaceutical Design and Engineering	Engels	5	140
	keuze	WMBS005-05	Tools and Approaches of Systems Biology	Engels	5
	keuze	WMBM015-05	Translational Research in Respiratory Disease	Engels	5
semester I b	keuze	WMFA042-05	Clinical Toxicology	Engels	5
	keuze	WMBY026-05	Laboratory Animal Science	Engels	5
	keuze	WMFA047-05	Nanomedicine and nanosafety	Engels	5
	keuze	WMBM018-05	Neurobiology of Psychiatric Disorders	Engels	5
	keuze	WMFA043-05	Pharmaceutical Biotechnology	Engels en Nederlands	5
	keuze	WMBY010-05	Programming C++ for Biologists	Engels	5
	keuze	WMBY011-05	Radioisotopes in Experimental Biology	Engels	5
semester II	keuze	TEM0105	Basiscursus Master Lerarenopleiding	Nederlands	5	variabel
	keuze	TEM0205	Masterstage 1 Lerarenopleiding	Nederlands	5	variabel
	keuze	WMBY014-05	Orientation on International Careers	Engels	5
semester II a	keuze	WMBM028-05	Applied Statistics and Machine Learning	Engels	5
	keuze	WMBM025-05	Big Data & Applications in Biomedicine	Engels	5
	keuze	WMFA049-05	Quantitative Bioanalysis	Engels	5
	keuze	WMEC006-05	Skills in Science Communication	Engels	5
	keuze	WMBS014-05	Transcriptomics	Engels	5
semester II b	keuze	WMBY016-05	Advanced Light Microscopy	Engels	5
	keuze	WMBY018-06	Advanced Statistics	Engels	6
	keuze	WMFA051-10	Medicinal Natural Products	Engels	10
	keuze	WMFA048-05	Pharmacology of Chronic Diseases and Ageing	Engels	5

Toon korte vakomschrijvingen

Academic Skills

WMMP012-05

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	prof. dr. E. Hak
Docent(en)	dr. S. de Vos prof. dr. T.L. Feenstra prof. dr. E. Hak
Onderwijsvorm	Bijeenkomst (S), Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC)
Toetsvorm	Opdracht (AST), Presentatie (P), Schriftelijk tentamen (WE)
ECTS	5

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Advanced Light Microscopy

WMBY016-05

In this course students learn various aspects of modern advanced light and fluorescence microscopy techniques. The course includes basic knowledge on light microscopy, several aspects of fluorescence microscopy, including the principles of fluorescence, properties of fluorescent dyes and proteins, wide field-, confocal-, SIM-, TIRF- and spinning disc microscopy, advanced fluorescence microscopy techniques such as FRET,FLIM and FCS as well as super resolution microscopy. Additional topics include live cell imaging, image processing and analysis and artifacts in fluorescence microscopy. The course consists of a theoretical part (lectures), practicals and a short research project. Assessment is via the preparation and presentation of a poster that contains the results of the research project and a written examination.

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	prof. dr. I.J. van der Klei
Docent(en)	dr. B.N.G. Giepmans dr. J.A.K.W. Kiel Dr. A. Milias Argeitis prof. dr. W.H. Roos prof. dr. D.J. Scheffers prof. dr. I.J. van der Klei dr. R. Vlijm
Onderwijsvorm	Hoorcollege (LC), Practisch werk (PRC)
Toetsvorm	Presentatie (P), Schriftelijk tentamen (WE), Practisch werk (PR)
ECTS	5
Entreevoorwaarden	The course unit assumes prior knowledge acquired from the Cell biology course in the first year Bachelor programme Biology/LS&T. It is recommended that students follow Cell Biology and Microscopy (or similar, basic microscopy course) before enrolling in this course unit.
Opmerkingen	There is a minimum of 6 students needed for this course. If there are less students when progress closes in March the course will be cancelled. Other lecturers: R.Lira

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Advanced Pharmacoeconomics

WMFA001-05

Students will learn to design, implement, and analyse health economic decision models. An important application of these models are
cost-effectiveness analyses. They will learn to judge what input data are needed to populate their model and from what sources
these can be obtained. Model types covered are: decision trees, macro level state transition models (Markov cohort models), and
patient-level models. The differences between these models, for example in how patient heterogeneity is handled, will be explored.
Several statistical techniques needed to obtain useful input data including parametric survival analysis will be discussed. Insight into
the role of sensitivity analysis and the different options for this will be given. This includes probabilistic sensitivity analysis and value
of information analysis.

Faculteit	Science and Engineering
Voertaal	Engels en Nederlands
Coordinator	prof. dr. T.L. Feenstra
Docent(en)	prof. dr. T.L. Feenstra dr. A.D.I. van Asselt
Onderwijsvorm	Practisch werk (PRC), Hoorcollege (LC), Opdracht (ASM)
Toetsvorm	Presentatie (P), Verslag (R)
ECTS	5
Entreevoorwaarden	Students are assumed to have a basic level of knowledge of economic evaluation at the level of the textbook by Drummond et al. e.g. obtained by attending the course Pharmacoeconomics, or the course Economic Evaluation in Healthcare. Students are also assumed to have knowledge of Microsoft Excel and to have a basic level of statistical knowledge. Students who have doubts about their background knowledge are advised to contact the course coordinator prior to the start date of the course.
Opmerkingen	Capacity is 15 students. Updated 29-04-2021 LW

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Advanced pharmacokinetics

WMMP005-05

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	P.H.C. Åberg, PhD.
Docent(en)	P.H.C. Åberg, PhD. P.J. Colin Guest Lecturer(s)dr. J. Stevens prof. dr. D.J. Touw
Onderwijsvorm	Hoorcollege (LC), Opdracht (ASM)
Toetsvorm	Opdracht (AST), Schriftelijk tentamen (WE)
ECTS	5

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Advanced Statistics

WMBY018-06

Content:

Introduction to R and review of basic statistics. Further topics: general linear models (ANOVA, ANCOVA, multiple regression); generalized least squares; mixed models; generalized linear models; generalized linear mixed models; Bayesian analysis and MCMC; animal models; multivariate analysis. During the last week of the course analysis and presentation of own data set.

Description:
This course teaches advanced statistical analysis almost from the ground up. The only requirement is some familiarity with basic statistical concepts and methods, such as taught in most introductory statistics courses. Some experience with R is useful but not crucial. During the first three days, basic methods and R will be reviewed to refresh your memory. During the next three weeks, cutting-edge techniques such as GLMMs, power analyses and Bayesian MCMC models will discussed and practiced. Each day will start with a review of the exercises of the previous day, followed by lectures and new computer labs. Mathematics will be kept to a minimum, and in addition to developing analytical skills, the course also puts much emphasis on producing effective and great-looking graphs (mostly using the ggplot2 package).

The last week of the course will be dedicated to analyzing your own data, unleashing the newly learned techniques. If you have no data yet, alternative suitable data will be found elsewhere or simply created de novo with simulation models. Your methods, results and conclusions will be documented in a report which will be graded.

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	prof. dr. I.R. Pen
Docent(en)	prof. dr. I.R. Pen prof. dr. G.S. van Doorn
Onderwijsvorm	Hoorcollege (LC), Practisch werk (PRC)
Toetsvorm	Verslag (R)
ECTS	6
Entreevoorwaarden	The course unit assumes some prior statistical knowledge and skills acquired from the bachelor courses in Biostatistics (I and II) or similar.

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Applied Statistics and Machine Learning

WMBM028-05

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	G.A. Lunter
Docent(en)
ECTS	5

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Basiscursus Master Lerarenopleiding

TEM0105

Bij dit vak doet de student basale kennis en vaardigheden op over het beroep als (vak)docent. Hij volgt daartoe (online) algemene colleges op het terrein van de pedagogiek en didactiek. Daarnaast neemt de student, onder leiding van de vakdidacticus, deel aan fysieke en/of online bijeenkomsten rond vakdidactiek. De student leert hoe een les te plannen en te evalueren, traint in het geven van deellessen, leert wat het betekent om voor een groep pubers te staan en wat hen motiveert en wat het belang is van een veilig leerklimaat. De student krijgt opdrachten mee die uitgevoerd worden in de onderwijspraktijk (Masterstage 1), leert hoe je gegevens verzamelt over die onderwijspraktijk (observaties, interviews, leerlingvragenlijsten) en hoe je die praktijk vanuit de theorie kunt analyseren. De student oriënteert zich daarmee op alles wat hem tijdens het vervolg van de opleiding te wachten staat en bouwt een realistisch beeld op van zijn geschiktheid voor dat vervolg.

Faculteit	Lerarenopleiding
Voertaal	Nederlands
Coordinator	C.A.M. Griep-Hoebink
Docent(en)
Onderwijsvorm	Hoor- en werkcolleges, Opdrachten, Zelfstudie
Toetsvorm	Schriftelijk eindproduct
ECTS	5
Entreevoorwaarden	Toegelaten tot de opleiding
Opmerkingen	Vakcoördinator: Carla Griep (tweejarige Educatieve Master) (c.a.m.griep-hoebink@rug.nl) Geke Schuurman (LVHO) (G.A.Schuurman@rug.nl) Aanmelden? Kijk dan op onze website voor meer informatie: https://www.rug.nl/gmw/lerarenopleiding/onderwijs/aanmelding-lerarenopleiding

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Behavioural Pharmacology

WMBC003-05

In this course the main psychiatric disorders (schizophrenia, depressive disorder, post-traumatic stress disorder, anxiety disorders, personality disorders and autism spectrum disorders) will be presented according to its current DSM-5 classification system. In addition, the novel emerging neuroscientific view will be presented that considers mental diseases as disorders of (multiple) brain circuit function that are connected to a particular behavioral domain (perception, motivation, emotional reactivity, motor control, flexibility, etc.). Although conventional behavioral animal models of different mental disorders are often used to study the etiology, physiology and treatment of the DSM-5 disorder, they cannot capture the full picture of the human disease. Discovering novel compounds for human neuropsychiatric diseases requires the development of valid and useful animal behavioral models for the specific disorder/domains under study. Therefore, whole animal psychopharmacology is of crucial importance for understanding the normal physiology of animals and for investigating the functional consequences of molecular or genetic modifications. With respect to brain (psychiatric and neurological) disorders, such models have proven to be notoriously difficult and, hence, many different models exist for each specific disease. The general objective of this course is to make students familiar with the basic principles, possibilities and pitfalls of the (psycho) pharmacological manipulation of whole animal behavior. This course will thoroughly address the current state of knowledge about animal models of mental illnesses with a focus on various personality and social behavioral disorders, stress-related (depression & anxiety) disorders, and substance-use disorders.

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	prof. dr. J.D.A. Olivier
Docent(en)	and others dr. B. Buwalda prof. dr. M.J.H. Kas prof. dr. J.D.A. Olivier
Onderwijsvorm	Hoorcollege (LC), Opdracht (ASM), Werkcollege (T)
Toetsvorm	Opdracht (AST), Presentatie (P), Schriftelijk tentamen (WE)
ECTS	5
Entreevoorwaarden	The course unit assumes no prior knowledge from specific introductory bachelor or master courses.
Opmerkingen	Capacity: maximum 20 students

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Big Data & Applications in Biomedicine

WMBM025-05

An increasing volume of data is becoming available in biomedicine and healthcare, from genomic, proteomics, to electronic patient records, (radiology) images and data collected by wearable devices. Recent advances in data science are transforming the life sciences, leading to precision medicine and stratified healthcare.

In this course, you will learn about some of the different types of data and computational methods involved in healthcare. You will have hands-on experience of working with such data from single cell-sequencing, multi-modular analysis from coupling neuro-imaging-behavior and genetics, and methylation- immunochemistry-proteomics from oncology. This course will show how the theory of statistical inferences and programming can be applied to advance medical research which ultimately benefit patient care.

Concepts for effective analysis of images such as thresholding, morphological operations (dilation, erosion, closing, opening), histogram equalization, will be explained before introducing convolutional neural networks with deep learning.

And you will learn from leaders in the field about successful case studies. Topics include: (i) Data Processing, (ii) Image Analysis, (iii) Network Learning and Modelling, (iv) Machine Learning.

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	dr. ir. P.M.A. van Ooijen
Docent(en)
Onderwijsvorm	Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC)
Toetsvorm	Practisch werk (PR), Schriftelijk tentamen (WE), Verslag (R)
ECTS	5
Entreevoorwaarden	Basics of programming and datamanagement Applied statistics and modelling

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Clinical Pharmacoepidemiology

WMMP015-05

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	prof. dr. E. Hak
Docent(en)	H.J. Bos, BSc.dr. S. de Vos prof. dr. T.L. Feenstra Guest Lecturer(s)prof. dr. E. Hak
Onderwijsvorm	Bijeenkomst (S), Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC)
Toetsvorm	Schriftelijk tentamen (WE), Tussentoets (IT)
ECTS	5

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Clinical Toxicology

WMFA042-05

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	prof. dr. D.J. Touw
Docent(en)	prof. dr. D.J. Touw
Onderwijsvorm	Bijeenkomst (S), Hoorcollege (LC), Opdracht (ASM)
Toetsvorm	Presentatie (P), Schriftelijk tentamen (WE)
ECTS	5
Opmerkingen	De vakcapaciteit is 48 studenten.

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Colloquium

WMMP001-05

Faculteit	Science and Engineering
Voertaal	Engels
Docent(en)
ECTS	5

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CPE - Basics in Medicine

GKCPE001

Faculteit	Medische Wetenschappen / UMCG
Voertaal	Engels
Coordinator	dr. H. Groen
Docent(en)
Onderwijsvorm	Colleges (patiënt-, thema-, magistraal, en responsie-colleges)
Toetsvorm	aanwezigheidsverplichting en schriftelijk tentamen
ECTS	8

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Drug Development: from Design to Evaluation

WMMP006-05

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	prof. dr. P. Olinga
Docent(en)	and others prof. dr. F.J. Dekker Prof. Dr. A.S.S. Dömling prof. dr. H.W. Frijlink prof. dr. E. Hak prof. dr. B.N. Melgert prof. dr. G. Molema Prof. Dr. A. Salvati
Onderwijsvorm	Opdracht (ASM), Hoorcollege (LC)
Toetsvorm	Opdracht (AST), Schriftelijk tentamen (WE)
ECTS	5

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Essay

WMMP002-05

Faculteit	Science and Engineering
Voertaal	Engels
Docent(en)
ECTS	5

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From Big Data to Personalised Medicine

WMBM008-05

This course will give students a complete, hands-on overview of the generation, analysis and applications of next generation sequencing (NGS) and big data in biomedical science, including genetics, gene expression, epigenetics, microbiome metagenomics, proteomics and single cell sequencing techniques. You will gain insight in how the analysis of multi-omics data can contribute to elucidating the biological processes that lead to diseases in several lectures from experts in the field of precision medicine, multi-omics and data analysis. Moreover, you will get hands-on experience during the practical: You will generate your own RNAseq big data set in the lab, which will be sequenced and analysed by you using R in a weeklong group assignment.

Together, you will get an overview of what it takes to generate big data and how this data can be processed and interpreted to understand how disease and treatment of disease can differ as a consequence of an individual's genetics and environment. The course is very hands-on and for a limited group of students only.

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	dr. I.H. Jonkers
Docent(en)	Guest lecturer dr. I.H. Jonkers dr. S. Withoff
Onderwijsvorm	Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC), Werkcollege (T)
Toetsvorm	Practisch werk (PR), Schriftelijk tentamen (WE), Verslag (R)
ECTS	5
Entreevoorwaarden	Basic molecular biology, basic genetics and introduction to statistics. Some experience with R is very useful.
Opmerkingen	This is a MSc. Biomedical Sciences course unit: see student portal for priority regulations. Capacity: maximum 30 students. Attendance during the practical and tutorials is mandatory, absence during the lectures is strongly advised against as the content of the lectures is material for the written exam. Absence during the assignment is only allowed with support of all members in the group, the grade for the group assignment per student can be adjusted for contribution to the final product. Guest lecturers are: Barbara Bakker, Kate McIntyre, Peter Horvatovich, Monique vd Wijst, Viktor Guryev, Sasha Zhernakova, Vinod Kumar, Inge Holtman, Joram Mooiweer, Jingyuan Fu

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Introduction Science and Business

WMSE001-10

This module will take place in two phases.

1. Theory Science and Business
2. Group project Science and Business

In the first three weeks you will follow an intensive program in which you get acquainted with important business concepts. After that you will train the skills to solve business cases and to write and present a feasible science advise to company owners. Most assignments will be done in groups and teams.

Final grade:
Exam theory after three weeks: 50%
Report after seven weeks: 50%
Personal portfolio: It does need to be a pass in order to receive the final grade
Subgrades need to be 5,5 or higher for a pass

For more information see https://www.rug.nl/research/irees/education/sciencebusinessandpolicy/.

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	drs. S. Grooters
Docent(en)	dr. C. Carroll prof. dr. G.J.W. Euverink drs. S. Grooters Irma Jager M.J. van den Nieuwenhof-Schilstra, MSc.dr. M. van Rijssel J. Zevenberg
Onderwijsvorm	Hoorcollege (LC), Practisch werk (PRC), Werkcollege (T)
Toetsvorm	Opdracht (AST), Schriftelijk tentamen (WE), Verslag (R)
ECTS	10
Entreevoorwaarden	The course unit assumes prior knowledge acquired from science-bachelor.
Opmerkingen	Capacity: Max. 100 students are participating in the course unit. The course unit is compulsory for the SBP track. This is a full-time course and all sessions are mandatory.

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Introduction Science and Policy

WMSE002-10

This module will take place in two phases.

1. Theory Science and Policy
2. Group project Science and Policy

In the first three weeks you will follow an intensive program in which you get acquainted with important policy concepts. After that you will train the skills to solve policy cases and to write and present a feasible science advise to governmental organisations. Most assignments will be done in groups and teams.

Final grade:
Exam theory after three weeks: 50%
Report after seven weeks: 50%
Personal portfolio: will not be graded. It does need to be a pass in order to receive the final grade
Subgrades need to be 5,5 or higher for a pass

For more information see https://www.rug.nl/research/irees/education/sciencebusinessandpolicy/.

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	drs. S. Grooters
Docent(en)	dr. B. Brink drs. S. Grooters dr. F.J. Sijtsma M.J. van den Nieuwenhof-Schilstra, MSc.prof. dr. H.B. Winter J. Zevenberg
Onderwijsvorm	Hoorcollege (LC), Practisch werk (PRC), Werkcollege (T)
Toetsvorm	Opdracht (AST), Schriftelijk tentamen (WE), Verslag (R)
ECTS	10
Entreevoorwaarden	The course unit assumes prior knowledge acquired from a science bachelor.
Opmerkingen	Capacity: Max. 100 students The course unit is compulsory for the SBP track This is full-time course and all sessions are mandatory

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Laboratory Animal Science

WMBY026-05

The aim of the course is to prepare students starting a master research project in which they participate in animal experimentation, which will be carried out during their master project under supervision of - and guided by the CCD permit holder. There are 2 versions of the course:

5 ECTS course
This MSc course will be aligned to the existing "art 9 course Laboratory Animal Science", which has been running already for several years and which prepares for a career in science requiring animal experimentation.
The 5ECTS version will consist of lectures and practicals, which offer insights into 1) Ethical considerations and the three R's, (2) Animal welfare and monitoring, (3) Rules & Regulations, (4) Research questions, experimental and statistical design, (5) Scientific Publication. At the end of the course there will be an exam which students have to pass in order to successfully finish it. Upon successful completion the 5 ECT version of this course, as well as successful finishing the masterproject for which this course was required, the student will receive the art.9 (Function B) certificate upon receiving the MSc diploma, which is mandatory for researchers who design and perform animal experiments (ex. art. 9 Wet op de Dierproeven (Experiments on Animals Act)).

2 ECTS version
The 2 ECT version of this course is more appropriate for those students who do not aim at a career in science requiring animal experimentation. This course allows students to do a master project in which they participate in animal experimentation, but since this course has a seriously reduced study load, the student will not be awarded the art 9. status.
The lectures and practicals of the 2 ECTS version will focus on 1) Ethical considerations and the three R's, 2) Animal welfare and monitoring and 3) Rules & Regulations.
This course will end with a less extensive exam. After succesfully finishing this course a certificate will be reached out.

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	prof. dr. G. van Dijk
Docent(en)	dr. C.M.A. Thuring prof. dr. E.M. van der Beek drs. M. van der Meulen-Frank dr. A. van Oosten
Onderwijsvorm	Bijeenkomst (S), Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC)
Toetsvorm	Meerkeuze toets (MC), Opdracht (AST), Practisch werk (PR), Schriftelijk tentamen (WE)
ECTS	5
Entreevoorwaarden	Students need to have completed their Bachelor Degree in Biology, Life Sciences and Technology, Biomedical Sciences, Medicine, or Pharmacy, or a comparable curriculum (if eg from abroad). A supervisor approved planning of a master research project involving animal experimentation is required. The course (either the 5 or the 2EC version) is compulsory for master students planning to work with animals during their research project.
Opmerkingen	Guest lecturers: P. Olinga, J.Sijbesma, J.E.T. van Wamel, A.M.A.C. Kosta, V. Pompe, J. van Ravenwaaij, R. van den Bos, K. Tamas, S. van der Werf, A. Epema, R. Thomas Maximum students: no maximum Course previously known as: Animal Experimentation

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Masterstage 1 Lerarenopleiding

TEM0205

Bij Masterstage 1 loopt de student stage op een school voor voortgezet onderwijs (in de regel twee dagen per week) onder begeleiding van een vakcoach. Hij verricht observaties, interviewt leerlingen, bereidt (deel)lessen voor, geeft ze en bespreekt ze na met de vakcoach. De student verzamelt informatie en feedback over de kwaliteit van het eigen handelen (o.a. door de afname van een leerlingenquête), rapporteert daarover en beschrijft zijn ervaringen in een stageverslag. De student oriënteert zich daarmee op het leraarschap en leert hoe je in de context van de school onderzoekend kunt werken aan het sturen van je ontwikkeling. In de context van de stage voert de student daarnaast opdrachten uit in het kader van de basiscursus lerarenopleiding (TEM0105), die parallel is georganiseerd aan de stage.

Faculteit	Lerarenopleiding
Voertaal	Nederlands
Coordinator	drs. S. Tuenter
Docent(en)	diverse docenten
Onderwijsvorm	Stage
Toetsvorm	Bekwaamheidsprofiel
ECTS	5
Entreevoorwaarden	Toegelaten tot de opleiding
Opmerkingen	Vakcoördinator: drs. Saskia Tuenter (s.tuenter@rug.nl) Aanmelden? Kijk dan op onze website voor meer informatie: https://www.rug.nl/gmw/lerarenopleiding/onderwijs/aanmelding-lerarenopleiding

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Medicinal Natural Products

WMFA051-10

De cursus is gericht op geneesmiddelen die uit de natuur geïsoleerd kunen worden. Deelnemers krijgen voor de duur van de cursus een onderzoeksproject. Hierbij worden eerst uit plantaardig materiaal natuurstoffen (b.v. alkaloiden, terpenoiden, flavonoiden) geïsoleerd volgens bestaande of nieuw te ontwikkelen voorschriften.
De geïsoleerde verbindingen worden geïdentificeerd en geanalyseerd m.b.v. TLC, IR, GC, GC-MS, HPLC, LC-MS en NMR (H1,C13). Tevens wordt de relevantie van deze analyses voor de werking als geneesmiddel onderwezen. De voortgang van de projecten wordt wekelijks met behulp van Powerpoint gepresenteerd. Binnen dit practicum wordt van de deelnemers een grote mate van zelfstandigheid en inventiviteit verwacht.

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	P.G. Tepper
Docent(en)	ing. R. Setroikromo P.G. Tepper
Onderwijsvorm	Practisch werk (PRC)
Toetsvorm	Practisch werk (PR), Presentatie (P), Verslag (R)
ECTS	10
Opmerkingen	Literatuur is beschikbaar bij de afdeling Farmaceutische Biologie Minimaal aantal studenten: 2 Maximaal aantal studenten: 10 Dit vak had vorig jaar vakcode WLFM1113

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Microbiological Safety

WMMP004-01

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	dr. B.L. Waarts
Docent(en)	dr. B.L. Waarts
Onderwijsvorm	Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC)
Toetsvorm	Meerkeuze toets (MC), Practisch werk (PR)
ECTS	1

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Molecular Toxicology

WMMP007-05

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	dr. ir. I.A.M. de Graaf
Docent(en)	dr. ir. I.A.M. de Graaf Prof. Dr. A. Salvati
Onderwijsvorm	Opdracht (ASM), Hoorcollege (LC)
Toetsvorm	Opdracht (AST), Presentatie (P), Schriftelijk tentamen (WE)
ECTS	5

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Nanomedicine and nanosafety

WMFA047-05

This course covers the following topics:
• nanomedicine for drug delivery and drug targeting
• nanomedicine applications other than drug delivery and drug targeting (organ-on-a-chip devices, tissue regeneration, stem cell differentiation and assisted surgery)
• overview of main classes of nanomedicines, such as lipid based drug carriers, polymer based drug carriers, inorganic nanoparticles, antibodies and immunoconjugates, biomimetic materials, viral based nanocarriers
• drug carriers and targeted drugs currently on the market and in clinical trials
• challenges in nanomaterial design for successful targeting and barriers to drug delivery;
• methods to characterize nano-sized drug carriers after synthesis and once applied in biological environments (size, charge, stability in biological fluids such as blood);
• behavior of nano-sized materials at cellular and and organism level (uptake, distribution, final fate, eventual effects on cellular functions);
• potential risks and safety concerns for nanomedicines and nano-sized materials not intended to be in contact with humans and living organisms (other nanotechnologies).

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	Prof. Dr. A. Salvati
Docent(en)	Gastdocent(en)Prof. Dr. A. Salvati dr. P. van Rijn prof. dr. E.M.J. Verpoorte
Onderwijsvorm	Bijeenkomst (S), Werkcollege (T)
Toetsvorm	Opdracht (AST), Presentatie (P), Schriftelijk tentamen (WE)
ECTS	5

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Neurobiology of Psychiatric Disorders

WMBM018-05

The current classification scheme for the diagnosis of psychiatric disorders, such as Schizophrenia and Autism, separates each into non-overlapping diagnostic categories. These diagnostic categories are sufficient to provide the basis for general clinical management, but do not describe the underlying neurobiology that gives rise to individual symptoms. The ability to precisely link these symptoms to underlying neurobiology would not only facilitate the development of better treatments, it would also allow physicians to provide patients with a better understanding of the complexities and management of their illness. To realize this ambition, a paradigm shift is needed to build an understanding of how neuropsychiatric diagnoses can be based on variation in quantitative biological parameters. The main difficulty in the construction of biologically valid diagnoses is the lack of objective biomarkers. Moreover, the uncertain relationship between diagnosis and underlying etiology has created difficulties for etiological research and made the generation of appropriate disease models and development of targeted treatments very difficult. As etiological research progresses, there has been a rethinking of these diagnostic boundaries and their usefulness in treatment and classification of neuropsychiatric disorders. For example, there is more etiological overlap between psychiatric and neurodegenerative disorders than previously thought, and that they may better be described as domains of cross-disorder-related traits (rather than separable categories) that can be translated to rodent models. This course will make students familiar with the basic principles, and provide insights into newly emerging developments in the field by linking psychiatry to neurobiology. Driven by advances in technologies and by knowledge on neural circuitry function, precision medicine approaches are under way to tackle cross-diagnostic overlap and clinical heterogeneity in psychiatric disorders.

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	prof. dr. M.J.H. Kas
Docent(en)	dr. M.J.H. Begemann prof. dr. W.H.I.M. Drinkenburg prof. dr. M.J.H. Kas prof. dr. I.E.C. Sommer prof. dr. M.J. van Tol
Onderwijsvorm	Hoorcollege (LC), Opdracht (ASM), Werkcollege (T)
Toetsvorm	Opdracht (AST), Presentatie (P)
ECTS	5
Entreevoorwaarden	No specific prior knowledge is required to participate in the course unit. The course is open to: MSc Biomedical Sciences, MSc Behavioural and Cognitive Neurosciences, MSc Biology, MSc Medical Pharmaceutical Sciences.
Opmerkingen	Capacity: maximum 40 students. This is a MSc. Biomedical Sciences course unit: see student portal for priority regulations in place.

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Orientation on International Careers

WMBY014-05

Research topics will be provided by participating companies or organizations. These research topics are typically centered on biotechnology and bioprocessing, ecology, population science or pharmaceutical science. Students are expected to investigate the literature and other sources on the assigned topic, and will work in interdisciplinary teams to combine their findings in written and oral reports. The students will be mentored by a supervisor, with whom they discuss their findings, prepare a written report and oral presentation, and receive a grade from. The completed work will be followed up with site visit to the participating companies. During the site visit each group will present their findings to the participating companies and hand over the written report. The companies will present themselves also during the site visit.

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	dr. B. Buwalda
Docent(en)	dr. B. Buwalda drs. S. Grooters prof. dr. T. Piersma
Onderwijsvorm	Werkcollege (T), Hoorcollege (LC), Opdracht (ASM)
Toetsvorm	Practisch werk (PR), Presentatie (P), Verslag (R)
ECTS	5
Entreevoorwaarden	The course unit does not assume prior knowledge acquired from other course units. The course unit is interesting for first year master students (Biology, BiMoS, EE, BMS, MB, MPS, Pharmacy) help the students in their choice for doing either a Research track or the Science, Business and Policy. For second year students who are doing the Research track it provides additional necessary information for building a future career outside the academy. For students who are already in the SBP track, this course has no added value because they already get this information in the SBP track. Students from Biology, Biomedical Sciences, Medical and Pharmaceutical Science, Biomolecular Sciences, Ecology and Evolution, Marine Biology, and Industrial Engineering and Management can register for the course.
Opmerkingen	Capacity: No maximum

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Pharmaceutical Biotechnology

WMFA043-05

Kennismaken met methoden voor moleculair biologisch en biotechnologisch onderzoek naar:
- De synthese en transformatie van farmaceutisch relevante verbindingen m.b.v. plantencel/weefselcultures, bacteriën en geïsoleerde enzymen.
- Het ontwikkelen van cytokines (eiwitten) en enzymen met veranderde eigenschappen door protein engineering/directed evolution.
- De secretie van biopharmaceuticals door bacteriën.
- Nieuwe mogelijkheden voor gentherapie.

Technieken: DNA-isolatie, Polymerase-kettingreactie (PCR), DNA-clonering, eiwit-expressie, eiwitisolatie, enzymassays, analyse van stoffen met HPLC en NMR, kweektechnieken voor bacteriën, humane cellen en/of plantencellen.

Faculteit	Science and Engineering
Voertaal	Engels en Nederlands
Coordinator	prof. dr. G.J. Poelarends
Docent(en)	prof. dr. G.J. Poelarends
Onderwijsvorm	Practisch werk (PRC)
Toetsvorm	Practisch werk (PR), Verslag (R)
ECTS	5
Opmerkingen	De voertaal is Engels als er internationale studenten deelnemen. Aantal deelnemers: Minimum: 2 Maximum: 10 Dit vak had vorig jaar vakcode WMFA13002

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Pharmaceutical Design and Engineering

WMMP008-05

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	prof. dr. F.J. Dekker
Docent(en)	prof. dr. F.J. Dekker prof. dr. H.W. Frijlink prof. dr. R. Gosens Prof. Dr. M.R. Groves dr. A.P. Nagelkerke prof. dr. G.J. Poelarends Prof. Dr. A. Salvati Prof. Dr. M. Schmidt
Onderwijsvorm	Opdracht (ASM), Hoorcollege (LC), Bijeenkomst (S)
Toetsvorm	Presentatie (P)
ECTS	5

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Pharmacoeconomics

WMFA040-05

An introduction to pharmacoeconomics, with a focus on economic evaluation (cost-effectiveness analysis).
The course consists of lectures, guest lectures and practicals. Next to this students will work on an assignment to critically assess a published cost-effectiveness study and practice model-based cost-effectiveness analysis by rebuilding the study model.

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	prof. dr. T.L. Feenstra
Docent(en)	dr. P.F.M. Krabbe dr. A.D.I. van Asselt
Onderwijsvorm	Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC)
Toetsvorm	Presentatie (P), Schriftelijk tentamen (WE)
ECTS	5
Opmerkingen	Capaciteit: Minimaal 10 studenten Maximaal 30 studenten

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Pharmaco-epidemiology in Practice

WMFA041-05

Colleges over Farmaco-epidemiologie worden gegeven ter verdieping op de basiscursus Farmaco-epidemiologie. Studenten werken epidemiologische opdrachten uit. Tevens wordt er een computerpracticum gegeven en hebben studenten 2 keer per week een contactuur met docenten.

Faculteit	Science and Engineering
Voertaal	Engels en Nederlands
Coordinator	dr. C.C.M. Schuiling-Veninga
Docent(en)	H.J. Bos, BSc.prof. dr. E. Hak dr. C.C.M. Schuiling-Veninga S.T. Visser
Onderwijsvorm	Bijeenkomst (S)
Toetsvorm	Presentatie (P)
ECTS	5
Opmerkingen	Deze cursus kan ook voor 10 ECTS gevolgd worden. Wanneer er buitenlandse studenten deelnemen, wordt deze cursus in het Engels gegeven. Capaciteit: Maximaal 10 studenten.

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Pharmacology of Chronic Diseases and Ageing

WMFA048-05

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	dr. H.A. Baarsma
Docent(en)	dr. H.A. Baarsma Prof. Dr. A.M. Dolga prof. dr. R. Gosens prof. dr. B.N. Melgert N. Musheshe A.M. Sabogal Guaqueta, MSc.Prof. Dr. M. Schmidt M. Trombetta Lima
Onderwijsvorm	Bijeenkomst (S), Hoorcollege (LC)
Toetsvorm	Presentatie (P), Verslag (R)
ECTS	5
Opmerkingen	This course unit will be given for the last time in 2021-2022.

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Pharmacovigilance (2022/2023)

WMMP011-05

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	prof. dr. E.P. van Puijenbroek
Docent(en)	R. van Eekeren-Buiten prof. dr. E.P. van Puijenbroek
Onderwijsvorm	Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC)
Toetsvorm	Meerkeuze toets (MC), Opdracht (AST)
ECTS	5

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Programming C++ for Biologists

WMBY010-05

This course, which is specifically designed for biology students, teaches the participants how to develop software in the programming language C++. Emphasis is given to the implementation of biological models, using individual-based simulations and various numerical methods for dynamical systems analysis.

Students are able to tailor the contents of the course to their own level of proficiency. For students with no prior programming experience, the course offers an introduction to the essentials of the C++ programming language, including:
• Procedural programming: data types, operators, program flow and functions
• The Standard Template Library
• Data input, generation of output including statistics like mean and standard deviation
• Numerical simulation techniques for biological models

More experienced programmers (including those who followed the BSc level course WBBY015-05) can instead focus on advanced topics, such as:
• Program design, algorithms and debugging
• Pointers and memory allocation
• Object-oriented programming
• Pseudo-random numbers and stochastic simulations

The course consists of two parts: during the first three weeks (5 ECTS), students extend their programming skills by learning a new element of the programming language each day, and practise its application in programming exercises. Students then have the option to apply their newly acquired skills in practice by working on an extended three-week programming project (+5 ECTS). Here, students work on a biological research question of their choice and design and implement a simulation algorithm from scratch. Students preparing for a theoretical MSc project, can use the project to develop a first implementation of the simulation code for their project. Participants also learn how to systematically collect simulation data, and to present their results in an oral presentation, with associated annotated program code and documentation.
The course is also available as a self-study course.

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	prof. dr. G.S. van Doorn
Docent(en)	and others dr. J. Bakker dr. T. Janzen prof. dr. G.S. van Doorn
Onderwijsvorm	Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC)
Toetsvorm	Opdracht (AST), Practisch werk (PR), Presentatie (P), Tussentoets (IT)
ECTS	5
Entreevoorwaarden	No specific entry requirements have been formulated for the course, except for elementary computer literacy.
Opmerkingen	Other lecturer: Dr. Claire Guerin Please note: there are multiple versions of this course. - Course WMBY010-10 is the 10 ECTS version at MSc level, with three weeks of classroom teaching + three weeks of project work; - WMBY010-05 is the 5 ECTS MSc level version, which has only three weeks of classroom teaching without project. Finally, WBBY015-05 is a three-week BSc level version of the course.

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Quantitative Bioanalysis

WMFA049-05

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	prof. dr. N.C. van de Merbel
Docent(en)	Prof. Dr. R.P.H. Bischoff Guest Lecturer(s)dr. H.P. Permentier prof. dr. N.C. van de Merbel
Onderwijsvorm	Bijeenkomst (S)
Toetsvorm	Schriftelijk tentamen (WE)
ECTS	5

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Radioisotopes in Experimental Biology

WMBY011-05

RPO Dispersible Radioactive Materials-D is the minimum expert level which allows you to work with radioisotopes at the university and university hospital (UMCG). It is an official expert level supervised and regulated by the Dutch Government. The University of Groningen is one of the few official recognized institutes were you can obtain certificates of the official radiation expert levels.
At the end of the 1st week you will HAVE to pass the RPO DRM-D test to be allowed to participate in the remainder of the course.

NOTE: For the course an additional registration is needed apart from Progress for participating in an official RPO DRM-D course.

Topics will include:
• Radioisotope detection using X-ray film
• The (advanced liquid) scintillation counter
• In vitro labeling of nucleic acids and proteins
• Subcellular localization of biological molecules
• Radioisotopes and immunoassay
• Pharmacological techniques
• Biological effect of radiation

The final part of the course consist of chronobiological research question regarding Melatonin using a Radioimmunoessay (RIA). The students will be their own research subjects. The results will be discussed in a concluding tutorial.

Location: Linnaeusborg (Center of Life Sciences), Zernike
During the curriculum year the course will be taught once in December.

Capacity: minimum 8, maximum 12 students for the course. First come, first serve.

For the course a second registration is needed (information will be provided in due time).
The exact timetable will depend on the (remaining) COVID19 restrictions.
Further information will be provided at least one month prior to the course.

(Master students who are only interested in obtaining the RPO DRM-D certificate have to contact the course coordinator for information about the other radiation courses (non curriculum courses)).

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	drs. E.J. Bunskoeke
Docent(en)	drs. E.J. Bunskoeke dr. M.H.K. Linskens dr. P. van Luijk E.I. Zuidersma, MSc.
Onderwijsvorm	Hoorcollege (LC), Practisch werk (PRC)
Toetsvorm	Meerkeuze toets (MC), Schriftelijk tentamen (WE), Verslag (R)
ECTS	5
Entreevoorwaarden	The course unit assumes no specific prior knowledge except a bachelor degree in an area of life-sciences (e.g. Biology, LS&T, Pharmacy, Medical Biology, Chemistry with biochemisty, etc.).
Opmerkingen	During the curriculum year the course will be taught once in December. For the course a second registration is needed (information will be provided in due time). The exact timetable will depend on the (remaining) COVID19 restrictions. Further information will be provided at least one month prior to the course. Master students who are only interested in obtaining the RPO DRM-D certificate have to contact the course coordinator for information about the other radiation courses (non curriculum courses). Capacity: Minimum 8, maximum 12 students for the course. First come, first serve Multiple choice test after week 1, to obtain certification. Minimal passing grade is 5.5 (out of 10). This exam has to be passed in order to continue with the remainder of the course. A final written exam: minimal 5 out of 10 to pass. Both exams and the assessment of the practical part contribute each 1/3 to the finale grade: the final grade is the average of these 3 grades.

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Reproductive Toxicology and Epidemiology

WMMP010-05

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	dr. C.C.M. Schuiling-Veninga
Docent(en)	dr. A.P. Nagelkerke dr. C.C.M. Schuiling-Veninga
Onderwijsvorm	Hoorcollege (LC), Practisch werk (PRC), Werkcollege (T)
Toetsvorm	Presentatie (P), Schriftelijk tentamen (WE), Verslag (R)
ECTS	5

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Research Project 1

WMMP901-40

Faculteit	Science and Engineering
Voertaal	Engels
Docent(en)
Onderwijsvorm	Opdracht (ASM), Practisch werk (PRC)
Toetsvorm	Opdracht (AST), Practisch werk (PR), Presentatie (P), Verslag (R)
ECTS	40

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Research Project 2

WMMP902-30

Faculteit	Science and Engineering
Voertaal	Engels
Docent(en)
Onderwijsvorm	Opdracht (ASM), Practisch werk (PRC)
Toetsvorm	Opdracht (AST), Practisch werk (PR), Presentatie (P), Verslag (R)
ECTS	30

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Skills in Science Communication

WMEC006-05

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	drs. L.T.J. Kraan
Docent(en)	Gastdocent(en)dr. D. Haydar drs. L.T.J. Kraan drs. L.R. Lutke
Onderwijsvorm	Hoorcollege (LC), Opdracht (ASM)
Toetsvorm	Presentatie (P), Verslag (R)
ECTS	5

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Tools and Approaches of Systems Biology

WMBS005-05

In the course, students should become familiar with the modern tools and approaches of systems biology. Specifically, the course will introduce
(i) the principles of the powerful omics measurement technologies, (ii) the computational concepts used to extract information from these large data sets, and (iii) how mathematical models can be used to investigate complex biological systems. These concepts and approaches will be illustrated with examples from metabolism-related research such that the students also gain further knowledge in this particular field of biology.

The course consists of three parts:
1) lectures, focusing on overview of tools with examples from recent literature;
2) practical work in which students perform computational analyses and develop their own mathematical models;
3) assignments in which students prepare short presentations on questions related torecent literature

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	Prof. Dr. M. Heinemann
Docent(en)	Prof. Dr. M. Heinemann
Onderwijsvorm	Hoorcollege (LC), Practisch werk (PRC), Werkcollege (T)
Toetsvorm	Practisch werk (PR), Schriftelijk tentamen (WE)
ECTS	5
Entreevoorwaarden	The course unit assumes prior knowledge acquired from a Bachelor programme that taught the basics of molecular biology, cell biology and biochemistry. Approx. 30 students from the above mentioned degree programme(s) are participating in the course unit. The course unit is one of the compulsory courses of the MSc Biomolecular Sciences degree programme, and an elective in other programmes.
Opmerkingen	Students from the degree programme Biomolecular Sciences have priority, to register please send an email to: academicadvisor.mscbio@rug.nl

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Transcriptomics

WMBS014-05

In this course, theory and practicals are combined to give an in-depth view of transcriptomics research in eukaryotes and prokaryotes. This master course is divided into three parts.

The first part focuses on the theoretical background of Next Generation Sequencing (DNA-Seq and RNA-Seq) and on how important the role of RNA is in modern science. The assessment for this part consists of a literature case study on ChIP-Seq in Eukaryotes.
The second part consists of 3 - 4 days lab work to practice working with RNA; quality control of the RNA, library preparation for Next Generation Sequencing and running samples on an Illumina sequencer. The projects selected for this part are based on research questions of PhD students and post-doctoral fellows of the department of Molecular Genetics. In principle the experiment has not been done before, which means that the generated data is novel.
The last part of the course concerns statistics and data analysis on High-Performance Computing required for transcriptome analyses. Students will analyze and draw conclusions on their own datasets and will link results to biological knowledge by using additional statistical methods. Also, based on their findings, students will be encouraged to propose ideas for further experiments.

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	dr. A. de Jong
Docent(en)	dr. A. de Jong D. Incarnato, PhD.prof. dr. J. Kok
Onderwijsvorm	Hoorcollege (LC), Practisch werk (PRC), Werkcollege (T)
Toetsvorm	Practisch werk (PR), Presentatie (P), Verslag (R)
ECTS	5
Entreevoorwaarden	The course assumes prior knowledge acquired from Microbiology & Genetics research or equivalent.
Opmerkingen	Students from the degree programme Biomolecular Sciences have priority, to register please send an email to: academicadvisor.mscbio@rug.nl Course coordinator: dr Anne de Jong, anne.de.jong@rug.nl, 050 363 2047 Location: Research group Molecular Genetics (GBB), Centre for Life Sciences. Students in Biomolecular Sciences have priority for this course. capacity: 24 students

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Translational Research in Respiratory Disease

WMBM015-05

The students will be introduced to translational research into complex respiratory diseases such as asthma, COPD and lung fibrosis. A multidisciplinary introduction into all relevant aspects of respiratory physiology and disease will be provided to the students: in the first one-and-a-half week, clinicians (pulmonology, pediatrics and pathologists) and scientists (biologists, epidemiologists, pharmacologists, bioinformaticians and geneticists) will offer a comprehensive overview of basic lung development, anatomy and physiology; clinical background on chronic lung diseases including the patients' perspective, diagnostic tools and current treatment options; state-of-the-art in translational research and recent technological advances in research, diagnosis and treatment. Students will be introduced to novel drug delivery technologies (devices and particle technologies) for targeted therapeutic approaches. In the second part, students will work in small groups under supervision of experienced bio-informaticians with a large dataset encompassing clinical and gene expression data, define a research question of their interest and perform the relevant analyses using the dataset to answer their research question. Students will use the results from their analyses and the knowledge acquired to design a research plan to develop a novel therapeutic approach for a chronic lung disease. This course will help students acquire the necessary translational research skills to effectively contribute to multidisciplinary research in chronic, complex diseases, also outside of the respiratory system.

Faculteit	Science and Engineering
Voertaal	Engels
Coordinator	prof. dr. J.K. Burgess
Docent(en)	prof. dr. J.K. Burgess prof. dr. R. Gosens Guest lecturer prof. dr. B.N. Melgert dr. ir. M.C. Nawijn M. van den Berge
Onderwijsvorm	Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC), Werkcollege (T)
Toetsvorm	Meerkeuze toets (MC), Opdracht (AST), Presentatie (P)
ECTS	5
Entreevoorwaarden	BSc in Biomedical Sciences (or equivalent)
Opmerkingen	Max. number of students: 18. This is a MSc. Biomedical Sciences course unit: see student portal for priority regulations in place. Other (guest)lecturers: Maaike de Vries, Irene Heijink, Wim Timens, Dirk Jan Slebos, Gerard Koppelman, Corry-Anke Brandsma, Tji Gan, Martina Schmidt, Alex Domling, Markus Weckmann

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