| 1 | Advanced Protein Crystallography | WMBS008-05 |
This course will provide insights on the important fundamentals and practices of protein X-ray crystallography. The aims of the course are to learn how protein crystal structures are determined, and to acquire the knowledge and skills necessary for critically analysing a 3D crystal structure.
Subjects discussed during the course are:
• Protein crystallization and crystal geometry;
• Basic diffraction theory;
• X-ray instrumentation;
• Strategies for phase determination;
• Basics of model building and refinement;
• Structure validation: quality assessment of a protein crystal structure.
Lecture classes are combined with discussion/exercise sessions: students will obtain reading assignments, will have to answer exercises, and are requested to prepare questions and subjects for group discussions. The lecture/discussion/exercise course is complemented with a workshop on the use of the various protein crystallographic computer programs. |
| Faculteit | Science and Engineering | | Voertaal | Engels | | Coordinator | dr. A.M.W.H. Thunnissen | | Docent(en) | Prof. Dr. A. Guskovdr. A.M.W.H. Thunnissen | | Onderwijsvorm | Hoorcollege (LC), Practisch werk (PRC) | | Toetsvorm | Practisch werk (PR), Schriftelijk tentamen (WE) | | ECTS | 5 | | Entreevoorwaarden | The course unit assumes prior knowledge acquired from relevant courses in Bachelor’s programmes in Chemistry and/or in Biology, covering the following subjects: fundamentals of protein structure, mathematics (basic calculus and vectors), biophysical chemistry. Relevant courses in the BSc Chemistry and BSc Biology or LS&T programmes at the University of Groningen: Calculus I (WICAL1-12), Biochemistry (CHBC-10), Recombinant DNA and Biotechnology (CHRDNAB-11), Cell physiology: Energy and Structure (WLP10B18), Structural Biology (WLP10B22), Mathematics for Life Sciences (WLP10B22). | | Opmerkingen | Students from the degree programme Biomolecular Sciences have priority, to register please send an email to: academicadvisor.mscbio@rug.nl
Maximum capacity is 24 students. |
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| 2 | Advances in Chemical Biology | WMCH014-05 |
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| 3 | Astrochemistry (21/22) | WMAS018-05 |
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| 4 | Bio-based Products | WMCE001-05 |
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| 5 | Biocatalysis and Green Chemistry | WMCH027-05 |
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| 6 | Bioinspired Designer Materials | WMCH009-05 |
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| 7 | Biomaterials 2 | WMBE001-05 |
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| Faculteit | Science and Engineering | | Voertaal | Engels | | Coordinator | dr. P. van Rijn | | Docent(en) | dr. P. van Rijn | | Onderwijsvorm | Bijeenkomst (S), Opdracht (ASM), Hoorcollege (LC) | | Toetsvorm | Opdracht (AST) | | ECTS | 5 |
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| 8 | Biophysical Imaging & Manipulation Techniques | WMPH047-05 |
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| Faculteit | Science and Engineering | | Voertaal | Engels | | Coordinator | prof. dr. W.H. Roos | | Docent(en) | prof. dr. W.H. Roos | | Onderwijsvorm | Hoorcollege (LC), Practisch werk (PRC), Werkcollege (T) | | Toetsvorm | Presentatie (P), Schriftelijk tentamen (WE), Verslag (R) | | ECTS | 5 |
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| 9 | Characterisation of Materials | WMPH021-05 |
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| 10 | Chemical Catalysis | WMCH015-05 |
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| 11 | Colloquium | WMCH001-05 |
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| Faculteit | Science and Engineering | | Voertaal | Engels | | Coordinator | C. Mayer, PhD. | | Docent(en) | C. Mayer, PhD. | | Onderwijsvorm | Werkcollege (T) | | Toetsvorm | Presentatie (P), Verslag (R) | | ECTS | 5 |
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| 12 | Computational Chemistry | WMCH022-05 |
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| 13 | Design of Industrial Catalysts | WMCE009-05 |
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| 14 | Final Exam | WMCH002-05 |
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| Faculteit | Science and Engineering | | Voertaal | Engels | | Coordinator | dr. R.W.A. Havenith | | Docent(en) | | | Toetsvorm | Mondeling tentamen (OR) | | ECTS | 5 |
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| 15 | Functional Properties | WMPH015-05 |
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| 16 | Interfacial engineering | WMCE003-05 |
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| 17 | Introduction Science and Business | WMSE001-10 |
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| 18 | Introduction Science and Policy | WMSE002-10 |
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| 19 | Molecular Dynamics | WMBS003-05 |
Together with experiment and theory, computational modeling is one of the three pillars of modern science. In chemistry as well as in life sciences, modeling of the interactions between molecules is essential to understand the emerging behavior of complex systems. In particular the Molecular Dynamics (MD) simulation technique provides a detailed view of the behavior of molecules in space and time, at a resolution that cannot be attained by any single experimental technique.
In a series of lectures, the underlying theory (statistical thermodynamics), the diversity of molecular models (atomistic, coarsegrained), and numerical techniques (integration of Newton's equations of motion) used in MD simulations will be discussed.
Applications of the technique will be shown, with a focus on simulation of biomolecular processes.
An important part of the course is hands-on experience using the GROMACS modeling software in a series of tutorials and practicals covering the basics of the techniques and selected applications, e.g. self-assembly of lipids in water or sampling the conformational space of proteins. |
| Faculteit | Science and Engineering | | Voertaal | Engels | | Coordinator | prof. dr. S.J. Marrink | | Docent(en) | dr. A.H. de Vriesprof. dr. S.J. Marrink | | Onderwijsvorm | Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC) | | Toetsvorm | Practisch werk (PR), Presentatie (P), Schriftelijk tentamen (WE) | | ECTS | 5 | | Entreevoorwaarden | The course unit assumes prior knowledge acquired from Calculus, Classical Mechanics, Introduction to Thermodynamics, and Structural Biology, all at Bachelor Life Science and Technology level. This material is offered in various Life Science, Chemistry, and Physics courses. | | Opmerkingen | Students from the degree programme Biomolecular Sciences have priority, to register please send an email to: academicadvisor.mscbio@rug.nl
Max. 30 students |
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| 20 | Molecular Quantum Mechanics 1 | WMCH010-05 |
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| 21 | Molecular Quantum Mechanics 2 | WMCH016-05 |
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| 22 | Organic Synthesis: Methods and Strategy 1 | WMCH017-05 |
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| 23 | Organic Synthesis, Methods and Strategy 2 | WMCH024-05 |
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| 24 | Organometallic Chemistry | WMCH018-05 |
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| Faculteit | Science and Engineering | | Voertaal | Engels | | Coordinator | prof. dr. E. Otten | | Docent(en) | prof. dr. E. Otten | | Onderwijsvorm | Hoorcollege (LC), Opdracht (ASM), Werkcollege (T) | | Toetsvorm | Opdracht (AST), Schriftelijk tentamen (WE) | | ECTS | 5 |
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| 25 | Photovoltaics Science and Energy | WMCH011-05 |
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| 26 | Physical Methods for Chemical Analysis | WMCH012-05 |
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| 27 | Polymer Physics | WMCH025-05 |
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| Faculteit | Science and Engineering | | Voertaal | Engels | | Coordinator | Prof. Dr. G. Portale | | Docent(en) | Prof. Dr. G. Portale | | Onderwijsvorm | Hoorcollege (LC), Opdracht (ASM), Werkcollege (T) | | Toetsvorm | Presentatie (P), Schriftelijk tentamen (WE), Verslag (R) | | ECTS | 5 |
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| 28 | Polymer products | WMCE005-05 |
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| 29 | Practical Physical Chemistry of Polymers | WMCH030-05 |
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| 30 | Product Focused Process Design | WMCE011-05 |
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| 31 | Reaction Mechanisms | WMCH006-05 |
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| 32 | Skills in Science Communication | WMEC006-05 |
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| 33 | Stereochemistry | WMCH013-05 |
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| 34 | Structure at Macro, Meso and Nano Scale | WMPH020-05 |
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| 35 | Structure determination with spectroscopic methods | WMCH008-05 |
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| 36 | Supramolecular chemistry | WMCH020-05 |
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| 37 | Sustainability for Engineers | WMIE020-05 |
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| Faculteit | Science and Engineering | | Voertaal | Engels | | Coordinator | dr. ir. G.H. Jonker | | Docent(en) | dr. ir. G.H. Jonker | | Onderwijsvorm | Hoorcollege (LC), Opdracht (ASM), Werkcollege (T) | | Toetsvorm | Opdracht (AST) | | ECTS | 5 |
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| 38 | Sustainable Electric Energy Storage | WMCH029-05 |
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| Faculteit | Science and Engineering | | Voertaal | Engels | | Coordinator | prof. dr. M. Tromp | | Docent(en) | | | ECTS | 5 |
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| 39 | Synthetic Biology and Systems Chemistry | WMCH021-05 |
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| 40 | Topics in chemistry with Python | WMCH028-05 |
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| 41 | Work placement Business & Policy | WMSE902-40 |
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